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For: Ye L, Wang T, Yang C, Tang L, Zhou J, Lv C, Gong Y, Jiang Z, Liu Z. Microsomal cytochrome P450-mediated metabolism of hypaconitine, an active and highly toxic constituent derived from Aconitum species. Toxicol Lett 2011;204:81-91. [PMID: 21550385 DOI: 10.1016/j.toxlet.2011.04.015] [Cited by in Crossref: 33] [Cited by in F6Publishing: 32] [Article Influence: 2.8] [Reference Citation Analysis]
Number Citing Articles
1 Li X, Ou X, Ni J, Xu Y, Zuo H, Fu Y, Yang C, Zhao Z, Li N, Zhou H, Zhang R, Liu Z, Fu L, Zhu L. Bulleyaconitine A is a sensitive substrate and competitive inhibitor of CYP3A4: One of the possible explanations for clinical adverse reactions. Toxicology and Applied Pharmacology 2022. [DOI: 10.1016/j.taap.2022.116024] [Reference Citation Analysis]
2 You G, Yang R, Wei Y, Hu W, Gan L, Xie C, Zheng Z, Liu Z, Liao R, Ye L. The detoxification effect of cytochrome P450 3A4 on gelsemine-induced toxicity. Toxicol Lett 2021;353:34-42. [PMID: 34627953 DOI: 10.1016/j.toxlet.2021.10.003] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
3 Mi L, Li YC, Sun MR, Zhang PL, Li Y, Yang H. A systematic review of pharmacological activities, toxicological mechanisms and pharmacokinetic studies on Aconitum alkaloids. Chin J Nat Med 2021;19:505-20. [PMID: 34247774 DOI: 10.1016/S1875-5364(21)60050-X] [Cited by in Crossref: 6] [Cited by in F6Publishing: 2] [Article Influence: 3.0] [Reference Citation Analysis]
4 Chen M, You G, Xie C, Yang R, Hu W, Zheng Z, Liu S, Ye L. Pharmacokinetics of metformin in collagen-induced arthritis rats. Biochem Pharmacol 2021;185:114413. [PMID: 33434538 DOI: 10.1016/j.bcp.2021.114413] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
5 Jiang Y, Yang Z, Zhang L, Yan R, Liu S, Yang H, Wan S, Li Z, Zhu Z, Ye L, Zhang J. The cytochrome P450 metabolic profiling of SMU-B in vitro, a novel small molecule tyrosine kinase inhibitor. J Pharm Biomed Anal 2020;188:113400. [PMID: 32554179 DOI: 10.1016/j.jpba.2020.113400] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.7] [Reference Citation Analysis]
6 Yang Z, Lin Y, Gao L, Zhou Z, Wang S, Dong D, Wu B. Circadian clock regulates metabolism and toxicity of Fuzi(lateral root of Aconitum carmichaeli Debx) in mice. Phytomedicine 2020;67:153161. [DOI: 10.1016/j.phymed.2019.153161] [Cited by in Crossref: 11] [Cited by in F6Publishing: 9] [Article Influence: 3.7] [Reference Citation Analysis]
7 Zhao M, Xing H, Chen M, Dong D, Wu B. Circadian clock-controlled drug metabolism and transport. Xenobiotica 2020;50:495-505. [PMID: 31544568 DOI: 10.1080/00498254.2019.1672120] [Cited by in Crossref: 15] [Cited by in F6Publishing: 15] [Article Influence: 3.8] [Reference Citation Analysis]
8 Lin Y, Zhou Z, Yang Z, Gao L, Wang S, Yu P, Wu B. Circadian Cyp3a11 metabolism contributes to chronotoxicity of hypaconitine in mice. Chemico-Biological Interactions 2019;308:288-93. [DOI: 10.1016/j.cbi.2019.05.049] [Cited by in Crossref: 15] [Cited by in F6Publishing: 15] [Article Influence: 3.8] [Reference Citation Analysis]
9 Sun R, Chen M, Hu Y, Lan Y, Gan L, You G, Yue M, Wang H, Xia B, Zhao J, Tang L, Cai Z, Liu Z, Ye L. CYP3A4/5 mediates the metabolic detoxification of humantenmine, a highly toxic alkaloid from Gelsemium elegans Benth. J Appl Toxicol 2019;39:1283-92. [PMID: 31119768 DOI: 10.1002/jat.3813] [Cited by in Crossref: 10] [Cited by in F6Publishing: 10] [Article Influence: 2.5] [Reference Citation Analysis]
10 He Y, Wei Z, Ci X, Xie Y, Yi X, Zeng Y, Li Y, Liu C. Effects of liquorice on pharmacokinetics of aconitine in rats. Xenobiotica 2019;49:1485-93. [DOI: 10.1080/00498254.2019.1579007] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 1.5] [Reference Citation Analysis]
11 Huang G, Yang L, Zhang Z, Ren S, Tang X, Zhou W, Wang Y, Ma Z, Gao S, Gao Y. Human PXR-mediated transcriptional activation of CYP3A4 by 'Fuzi' extracts. Toxicol Mech Methods 2019;29:155-64. [PMID: 30303438 DOI: 10.1080/15376516.2018.1534296] [Cited by in Crossref: 3] [Cited by in F6Publishing: 4] [Article Influence: 0.8] [Reference Citation Analysis]
12 Hao D. Drug Metabolism and Pharmacokinetic Diversity of Ranunculaceae Medicinal Compounds. Ranunculales Medicinal Plants 2019. [DOI: 10.1016/b978-0-12-814232-5.00004-6] [Reference Citation Analysis]
13 Jin SE, Ha H, Shin HK. Effects of Herbal Formulas Bojungikgi-tang and Palmijihwang-hwan on Inflammation in RAW 264.7 Cells and the Activities of Drug-Metabolizing Enzymes in Human Hepatic Microsomes. J Med Food 2018;21:1173-87. [PMID: 30457473 DOI: 10.1089/jmf.2017.4123] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 1.4] [Reference Citation Analysis]
14 Wu J, Guo Z, Zhu Y, Huang Z, Gong X, Li Y, Son W, Li X, Lou Y, Zhu L, Lu L, Liu Z, Liu L. A systematic review of pharmacokinetic studies on herbal drug Fuzi : Implications for Fuzi as personalized medicine. Phytomedicine 2018;44:187-203. [DOI: 10.1016/j.phymed.2018.03.001] [Cited by in Crossref: 58] [Cited by in F6Publishing: 61] [Article Influence: 11.6] [Reference Citation Analysis]
15 Dai K, Yi X, Huang X, Muhammad A, Li M, Li J, Yang G, Gao Y. Hepatoprotective activity of iridoids, seco-iridoids and analog glycosides from Gentianaceae on HepG2 cells via CYP3A4 induction and mitochondrial pathway. Food Funct 2018;9:2673-83. [DOI: 10.1039/c8fo00168e] [Cited by in Crossref: 23] [Cited by in F6Publishing: 23] [Article Influence: 4.6] [Reference Citation Analysis]
16 Zhang M, Peng C, Li X. Human intestine and liver microsomal metabolic differences between C19-diester and monoester diterpenoid alkaloids from the roots of Aconitum carmichaelii Debx. Toxicology in Vitro 2017;45:318-33. [DOI: 10.1016/j.tiv.2017.09.011] [Cited by in Crossref: 13] [Cited by in F6Publishing: 13] [Article Influence: 2.2] [Reference Citation Analysis]
17 Yu Y, Yi X, Mei Z, Li J, Huang X, Yang G, Ma L, Gao Y. The water extract of Veratrilla baillonii could attenuate the subacute toxicity induced by Aconitum brachypodum. Phytomedicine 2016;23:1591-8. [DOI: 10.1016/j.phymed.2016.10.001] [Cited by in Crossref: 11] [Cited by in F6Publishing: 11] [Article Influence: 1.6] [Reference Citation Analysis]
18 Sun B, Wang X, Cao R, Zhang Q, Liu Q, Xu M, Zhang M, Du X, Dong F, Yan X. NMR-based metabonomics study on the effect of Gancao in the attenuation of toxicity in rats induced by Fuzi. J Ethnopharmacol 2016;193:617-26. [PMID: 27746335 DOI: 10.1016/j.jep.2016.10.042] [Cited by in Crossref: 22] [Cited by in F6Publishing: 21] [Article Influence: 3.1] [Reference Citation Analysis]
19 Yang B, Xu Y, Wu Y, Wu H, Wang Y, Yuan L, Xie J, Li Y, Zhang Y. Simultaneous determination of ten Aconitum alkaloids in rat tissues by UHPLC⿿MS/MS and its application to a tissue distribution study on the compatibility of Heishunpian and Fritillariae thunbergii Bulbus. Journal of Chromatography B 2016;1033-1034:242-9. [DOI: 10.1016/j.jchromb.2016.08.033] [Cited by in Crossref: 6] [Cited by in F6Publishing: 6] [Article Influence: 0.9] [Reference Citation Analysis]
20 Xu T, Liu S, Meng L, Pi Z, Song F, Liu Z. Bioactive heterocyclic alkaloids with diterpene structure isolated from traditional Chinese medicines. Journal of Chromatography B 2016;1026:56-66. [DOI: 10.1016/j.jchromb.2015.09.023] [Cited by in Crossref: 8] [Cited by in F6Publishing: 8] [Article Influence: 1.1] [Reference Citation Analysis]
21 Zhang N, Li J, Song Q, Shi S, Li C, Zhao Y, Song Y, Tu P. Direct stability characterization of aconite alkaloids in different media by autosampler-mediated incubation-online solid phase extraction-LC-MS/MS. Anal Methods 2016;8:1942-9. [DOI: 10.1039/c5ay02484f] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 0.6] [Reference Citation Analysis]
22 Liu W, Shi J, Zhu L, Dong L, Luo F, Zhao M, Wang Y, Hu M, Lu L, Liu Z. Reductive metabolism of oxymatrine is catalyzed by microsomal CYP3A4. Drug Des Devel Ther 2015;9:5771-83. [PMID: 26586934 DOI: 10.2147/DDDT.S92276] [Cited by in Crossref: 14] [Cited by in F6Publishing: 15] [Article Influence: 1.8] [Reference Citation Analysis]
23 Yang S, Zhang H, Beier RC, Sun F, Cao X, Shen J, Wang Z, Zhang S. Comparative metabolism of Lappaconitine in rat and human liver microsomes and in vivo of rat using ultra high-performance liquid chromatography-quadrupole/time-of-flight mass spectrometry. J Pharm Biomed Anal 2015;110:1-11. [PMID: 25796978 DOI: 10.1016/j.jpba.2015.02.048] [Cited by in Crossref: 19] [Cited by in F6Publishing: 19] [Article Influence: 2.4] [Reference Citation Analysis]
24 Zhang M, Peng CS, Li XB. In vivo and in vitro metabolites from the main diester and monoester diterpenoid alkaloids in a traditional chinese herb, the aconitum species. Evid Based Complement Alternat Med 2015;2015:252434. [PMID: 25705235 DOI: 10.1155/2015/252434] [Cited by in Crossref: 5] [Cited by in F6Publishing: 10] [Article Influence: 0.6] [Reference Citation Analysis]
25 Song Y, Zhang N, Jiang Y, Li J, Zhao Y, Shi S, Tu P. Simultaneous determination of aconite alkaloids and ginsenosides using online solid phase extraction hyphenated with polarity switching ultra-high performance liquid chromatography coupled with tandem mass spectrometry. RSC Adv 2015;5:6419-28. [DOI: 10.1039/c4ra14088e] [Cited by in Crossref: 22] [Cited by in F6Publishing: 22] [Article Influence: 2.8] [Reference Citation Analysis]
26 Bi Y, Zhuang X, Zhu H, Song F, Liu Z, Liu S. Studies on metabolites and metabolic pathways of bulleyaconitine A in rat liver microsomes using LC-MS n combined with specific inhibitors: Metabolites and metabolic pathways of bulleyaconitine A in CYP450. Biomed Chromatogr 2015;29:1027-34. [DOI: 10.1002/bmc.3388] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 0.8] [Reference Citation Analysis]
27 Yang H, Liu L, Gao W, Liu K, Qi L, Li P. Direct and comprehensive analysis of ginsenosides and diterpene alkaloids in Shenfu injection by combinatory liquid chromatography–mass spectrometric techniques. Journal of Pharmaceutical and Biomedical Analysis 2014;92:13-21. [DOI: 10.1016/j.jpba.2013.12.041] [Cited by in Crossref: 34] [Cited by in F6Publishing: 36] [Article Influence: 3.8] [Reference Citation Analysis]
28 Sun X, Liu T, Zhao Y, Zou W, Wang J, Liu S, Sun Z, Li R, Zhou X, Gong M, Wang R. Toxicity of Five Herbs in Aconitum L. on Tetrahymena thermophila Based on Spectrum-effect Relationship. Chinese Herbal Medicines 2014;6:29-35. [DOI: 10.1016/s1674-6384(14)60003-4] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.2] [Reference Citation Analysis]
29 Liu W, Liu H, Sun H, Dong D, Ma Z, Wang Y, Wu B. Metabolite elucidation of the Hsp90 inhibitor SNX-2112 using ultraperformance liquid chromatography/quadrupole time-of-flight mass spectrometry (UPLC-QTOF/MS). Xenobiotica 2013;44:455-64. [DOI: 10.3109/00498254.2013.853849] [Cited by in Crossref: 19] [Cited by in F6Publishing: 23] [Article Influence: 1.9] [Reference Citation Analysis]
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31 Zhu L, Yang X, Zhou J, Tang L, Xia B, Hu M, Zhou F, Liu Z. The exposure of highly toxic aconitine does not significantly impact the activity and expression of cytochrome P450 3A in rats determined by a novel ultra performance liquid chromatography-tandem mass spectrometric method of a specific probe buspirone. Food Chem Toxicol 2013;51:396-403. [PMID: 23085095 DOI: 10.1016/j.fct.2012.10.008] [Cited by in Crossref: 18] [Cited by in F6Publishing: 18] [Article Influence: 1.6] [Reference Citation Analysis]
32 Shen H, Wu J, Di L, Zhu L, Xu J, Yan R, Li S. Enhancement by Glycyrrhizae Radix of hepatic metabolism of hypaconitine, a major bioactive and toxic component of Aconiti Laterlis Radix, evaluated by HPLC-TQ-MS/MS analysis: Glycyrrhizae Radix enhances hepatic metabolism of hypaconitine. Biomed Chromatogr 2013;27:556-62. [DOI: 10.1002/bmc.2825] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 0.4] [Reference Citation Analysis]
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