Cell-free mitochondrial DNA quantification in ischemic stroke patients for non-invasive and real-time monitoring of disease status

Figure 4 Multiple comparison test showing intergroup differences in NADH dehydrogenase 1 relative expression levels and its diagnostic significance. A: Significantly decreased NADH dehydrogenase 1 (ND1) relative expression levels were observed after 24 h and 72 h of treatment compared to patients at disease onset (^bP < 0.001) and were comparable to controls; B-D: Receiver operating characteristic plots show the association of ND1 expression levels between patients at disease onset, 24 h of treatment, and 72 h of treatment. ^bP < 0.001; ^cP < 0.0001. AUC: Area under curve; ND1: NADH dehydrogenase 1; ROC: Receiver operating characteristic.