Copyright ©The Author(s) 2015.
World J Virology. Aug 12, 2015; 4(3): 295-302
Published online Aug 12, 2015. doi: 10.5501/wjv.v4.i3.295
Figure 1
Figure 1 Genome structure of the foot-and-mouth disease virus. Describes in details the different regions of foot-and-mouth disease virus (FMDV) which codes four structural and 8 non-structural proteins. The regions of genome encoding structural proteins are targeted for FMDV serotype determination by various assays, whereas the genome regions coding for non-structural proteins are targeted for serotype independent diagnosis. The SP of FMDV is targeted for serotyping by antigen trapping enzyme-linked immunosorbent assay (ELISA) or for measurement of antibody response by liquid phase blocking ELISA. Antibodies against various non-structural proteins are targeted for differentiation of FMD infected from vaccinated animals.