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For: Iraji A, Khoshneviszadeh M, Firuzi O, Khoshneviszadeh M, Edraki N. Novel small molecule therapeutic agents for Alzheimer disease: Focusing on BACE1 and multi-target directed ligands. Bioorg Chem 2020;97:103649. [PMID: 32101780 DOI: 10.1016/j.bioorg.2020.103649] [Cited by in Crossref: 24] [Cited by in F6Publishing: 18] [Article Influence: 12.0] [Reference Citation Analysis]
Number Citing Articles
1 Zarenezhad E, Farjam M, Iraji A. Synthesis and biological activity of pyrimidines-containing hybrids: Focusing on pharmacological application. Journal of Molecular Structure 2021;1230:129833. [DOI: 10.1016/j.molstruc.2020.129833] [Cited by in Crossref: 14] [Cited by in F6Publishing: 6] [Article Influence: 14.0] [Reference Citation Analysis]
2 Otani T, Hattori Y, Akaji K, Kobayashi K. Macrocyclic BACE1 inhibitors with hydrophobic cross-linked structures: Optimization of ring size and ring structure. Bioorg Med Chem 2021;52:116517. [PMID: 34800875 DOI: 10.1016/j.bmc.2021.116517] [Reference Citation Analysis]
3 Saeedi M, Safavi M, Allahabadi E, Rastegari A, Hariri R, Jafari S, Bukhari SNA, Mirfazli SS, Firuzi O, Edraki N, Mahdavi M, Akbarzadeh T. Thieno[2,3-b]pyridine amines: Synthesis and evaluation of tacrine analogs against biological activities related to Alzheimer's disease. Arch Pharm (Weinheim) 2020;353:e2000101. [PMID: 32657467 DOI: 10.1002/ardp.202000101] [Cited by in Crossref: 2] [Article Influence: 1.0] [Reference Citation Analysis]
4 Wang L, Xia H, Wu Y, Wang Y, Lin P, Lin S. Secoyanhusamine A, an Oxidatively Ring-Opened Isoquinoline Inner Salt From Corydalis yanhusuo. Front Chem 2022;9:831173. [DOI: 10.3389/fchem.2021.831173] [Reference Citation Analysis]
5 Yu TW, Lane HY, Lin CH. Novel Therapeutic Approaches for Alzheimer's Disease: An Updated Review. Int J Mol Sci 2021;22:8208. [PMID: 34360973 DOI: 10.3390/ijms22158208] [Reference Citation Analysis]
6 Mozaffarnia S, Teimuri-mofrad R, Rashidi M. Synthesis of 2-amino-3-cyano-4H-pyran derivatives using GO-Fc@Fe3O4 nanohybrid as a novel recyclable heterogeneous nanocatalyst and preparation of tacrine-naphthopyran hybrids as AChE inhibitors. J IRAN CHEM SOC 2021;18:1455-70. [DOI: 10.1007/s13738-020-02125-4] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 2.0] [Reference Citation Analysis]
7 Ugbaja SC, Sanusi ZK, Appiah-Kubi P, Lawal MM, Kumalo HM. Computational modelling of potent β-secretase (BACE1) inhibitors towards Alzheimer's disease treatment. Biophys Chem 2021;270:106536. [PMID: 33387910 DOI: 10.1016/j.bpc.2020.106536] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
8 Bais J, Benedetti F, Berti F, Cerminara I, Drioli S, Funicello M, Regini G, Vidali M, Felluga F. One Pot Synthesis of Micromolar BACE-1 Inhibitors Based on the Dihydropyrimidinone Scaffold and Their Thia and Imino Analogues. Molecules 2020;25:E4152. [PMID: 32927879 DOI: 10.3390/molecules25184152] [Cited by in Crossref: 3] [Article Influence: 1.5] [Reference Citation Analysis]
9 Saeedi M, Maleki A, Iraji A, Hariri R, Akbarzadeh T, Edraki N, Firuzi O, Mirfazli SS. Synthesis and bio-evaluation of new multifunctional methylindolinone-1,2,3-triazole hybrids as anti-Alzheimer's agents. Journal of Molecular Structure 2021;1229:129828. [DOI: 10.1016/j.molstruc.2020.129828] [Cited by in Crossref: 5] [Cited by in F6Publishing: 4] [Article Influence: 5.0] [Reference Citation Analysis]
10 Pont C, Ginex T, Griñán-Ferré C, Scheiner M, Mattellone A, Martínez N, Arce EM, Soriano-Fernández Y, Naldi M, De Simone A, Barenys M, Gómez-Catalán J, Pérez B, Sabate R, Andrisano V, Loza MI, Brea J, Bartolini M, Bolognesi ML, Decker M, Pallàs M, Luque FJ, Muñoz-Torrero D. From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects. Eur J Med Chem 2021;225:113779. [PMID: 34418785 DOI: 10.1016/j.ejmech.2021.113779] [Reference Citation Analysis]
11 Cunha S, Forbes B, Sousa Lobo JM, Silva AC. Improving Drug Delivery for Alzheimer's Disease Through Nose-to-Brain Delivery Using Nanoemulsions, Nanostructured Lipid Carriers (NLC) and in situ Hydrogels. Int J Nanomedicine 2021;16:4373-90. [PMID: 34234432 DOI: 10.2147/IJN.S305851] [Reference Citation Analysis]
12 Saeedi M, Felegari P, Iraji A, Hariri R, Rastegari A, Mirfazli SS, Edraki N, Firuzi O, Mahdavi M, Akbarzadeh T. Novel N-benzylpiperidine derivatives of 5-arylisoxazole-3-carboxamides as anti-Alzheimer's agents. Arch Pharm (Weinheim) 2021;354:e2000258. [PMID: 33226157 DOI: 10.1002/ardp.202000258] [Reference Citation Analysis]
13 Tang XH, Luo RC, Ye MS, Tang HY, Ma YL, Chen YN, Wang XM, Lu QY, Liu S, Li XN, Yan Y, Yang J, Ran XQ, Fang X, Zhou Y, Yao YG, Di YT, Hao XJ. Harpertrioate A, an A,B,D-seco-Limonoid with Promising Biological Activity against Alzheimer's Disease from Twigs of Harrisonia perforata (Blanco) Merr. Org Lett 2021;23:262-7. [PMID: 33284631 DOI: 10.1021/acs.orglett.0c03460] [Cited by in Crossref: 1] [Cited by in F6Publishing: 2] [Article Influence: 0.5] [Reference Citation Analysis]
14 Sampietro A, Pérez-areales FJ, Martínez P, Arce EM, Galdeano C, Muñoz-torrero D. Unveiling the Multitarget Anti-Alzheimer Drug Discovery Landscape: A Bibliometric Analysis. Pharmaceuticals 2022;15:545. [DOI: 10.3390/ph15050545] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
15 Ribaudo G, Ongaro A, Zagotto G, Memo M, Gianoncelli A. Therapeutic Potential of Phosphodiesterase Inhibitors against Neurodegeneration: The Perspective of the Medicinal Chemist. ACS Chem Neurosci 2020;11:1726-39. [PMID: 32401481 DOI: 10.1021/acschemneuro.0c00244] [Cited by in Crossref: 14] [Cited by in F6Publishing: 13] [Article Influence: 7.0] [Reference Citation Analysis]
16 Zhang X, Zhang X, Zhong M, Zhao P, Guo C, Li Y, Xu H, Wang T, Gao H. A Novel Cu(II)-Binding Peptide Identified by Phage Display Inhibits Cu2+-Mediated Aβ Aggregation. Int J Mol Sci 2021;22:6842. [PMID: 34202166 DOI: 10.3390/ijms22136842] [Reference Citation Analysis]
17 Haghighijoo Z, Akrami S, Saeedi M, Zonouzi A, Iraji A, Larijani B, Fakherzadeh H, Sharifi F, Arzaghi SM, Mahdavi M, Edraki N. N-Cyclohexylimidazo[1,2-a]pyridine derivatives as multi-target-directed ligands for treatment of Alzheimer's disease. Bioorganic Chemistry 2020;103:104146. [DOI: 10.1016/j.bioorg.2020.104146] [Cited by in Crossref: 3] [Cited by in F6Publishing: 2] [Article Influence: 1.5] [Reference Citation Analysis]
18 Shayegan N, Iraji A, Bakhshi N, Moazzam A, Faramarzi MA, Mojtabavi S, Pour SMM, Tehrani MB, Larijani B, Rezaei Z, Yousefi P, Khoshneviszadeh M, Mahdavi M. Design, synthesis, and in silico studies of benzimidazole bearing phenoxyacetamide derivatives as α-glucosidase and α-amylase inhibitors. Journal of Molecular Structure 2022. [DOI: 10.1016/j.molstruc.2022.133650] [Reference Citation Analysis]
19 Kobayashi K, Otani T, Ijiri S, Kawasaki Y, Matsubara H, Miyagi T, Kitajima T, Iseki R, Ishizawa K, Shindo N, Okawa K, Ueda K, Ando S, Kawakita M, Hattori Y, Akaji K. Structure-activity relationship study of hydroxyethylamine isostere and P1' site structure of peptide mimetic BACE1 inhibitors. Bioorg Med Chem 2021;50:116459. [PMID: 34700240 DOI: 10.1016/j.bmc.2021.116459] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
20 Qiao O, Ji H, Zhang Y, Zhang X, Zhang X, Liu N, Huang L, Liu C, Gao W. New insights in drug development for Alzheimer's disease based on microglia function. Biomed Pharmacother 2021;140:111703. [PMID: 34083109 DOI: 10.1016/j.biopha.2021.111703] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
21 Gontijo VS, Viegas FPD, Ortiz CJC, de Freitas Silva M, Damasio CM, Rosa MC, Campos TG, Couto DS, Tranches Dias KS, Viegas C. Molecular Hybridization as a Tool in the Design of Multi-target Directed Drug Candidates for Neurodegenerative Diseases. Curr Neuropharmacol 2020;18:348-407. [PMID: 31631821 DOI: 10.2174/1385272823666191021124443] [Cited by in Crossref: 14] [Cited by in F6Publishing: 12] [Article Influence: 7.0] [Reference Citation Analysis]
22 Wang D, Chen F, Han Z, Yin Z, Ge X, Lei P. Relationship Between Amyloid-β Deposition and Blood-Brain Barrier Dysfunction in Alzheimer's Disease. Front Cell Neurosci 2021;15:695479. [PMID: 34349624 DOI: 10.3389/fncel.2021.695479] [Cited by in F6Publishing: 1] [Reference Citation Analysis]
23 Romanucci V, Giordano M, De Tommaso G, Iuliano M, Bernini R, Clemente M, Garcia-Viñuales S, Milardi D, Zarrelli A, Di Fabio G. Synthesis of New Tyrosol-Based Phosphodiester Derivatives: Effect on Amyloid β Aggregation and Metal Chelation Ability. ChemMedChem 2021;16:1172-83. [PMID: 33326184 DOI: 10.1002/cmdc.202000807] [Cited by in Crossref: 1] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
24 Mansinhos I, Gonçalves S, Rodríguez-Solana R, Ordóñez-Díaz JL, Moreno-Rojas JM, Romano A. Ultrasonic-Assisted Extraction and Natural Deep Eutectic Solvents Combination: A Green Strategy to Improve the Recovery of Phenolic Compounds from Lavandula pedunculata subsp. lusitanica (Chaytor) Franco. Antioxidants (Basel) 2021;10:582. [PMID: 33918721 DOI: 10.3390/antiox10040582] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 2.0] [Reference Citation Analysis]
25 Pawelczak P, Fedoruk-wyszomirska A, Wyszko E. Antiaging Effect of 4-N-Furfurylcytosine in Yeast Model Manifests through Enhancement of Mitochondrial Activity and ROS Reduction. Antioxidants 2022;11:850. [DOI: 10.3390/antiox11050850] [Reference Citation Analysis]
26 Karimi Askarani H, Iraji A, Rastegari A, Abbas Bukhari SN, Firuzi O, Akbarzadeh T, Saeedi M. Design and synthesis of multi-target directed 1,2,3-triazole-dimethylaminoacryloyl-chromenone derivatives with potential use in Alzheimer's disease. BMC Chem 2020;14:64. [PMID: 33134975 DOI: 10.1186/s13065-020-00715-0] [Cited by in Crossref: 3] [Article Influence: 1.5] [Reference Citation Analysis]
27 Attarroshan M, Firuzi O, Iraji A, Sharifi S, Tavakkoli M, Vesal M, Khoshneviszadeh M, Pirhadi S, Edraki N. Imino-2H-Chromene Based Derivatives as Potential Anti-Alzheimer's Agents: Design, Synthesis, Biological Evaluation and in Silico Study. Chem Biodivers 2021;:e2100599. [PMID: 34786830 DOI: 10.1002/cbdv.202100599] [Reference Citation Analysis]
28 Zhou X, Hu S, Wang S, Pang Y, Lin Y, Li M. Large Amino Acid Mimicking Selenium-Doped Carbon Quantum Dots for Multi-Target Therapy of Alzheimer's Disease. Front Pharmacol 2021;12:778613. [PMID: 34776988 DOI: 10.3389/fphar.2021.778613] [Reference Citation Analysis]
29 Fasina OB, Wang J, Mo J, Osada H, Ohno H, Pan W, Xiang L, Qi J. Gastrodin From Gastrodia elata Enhances Cognitive Function and Neuroprotection of AD Mice via the Regulation of Gut Microbiota Composition and Inhibition of Neuron Inflammation. Front Pharmacol 2022;13:814271. [PMID: 35721206 DOI: 10.3389/fphar.2022.814271] [Reference Citation Analysis]
30 Wang D, Zhang S, Ge X, Yin Z, Li M, Guo M, Hu T, Han Z, Kong X, Li D, Zhao J, Wang L, Liu Q, Chen F, Lei P. Mesenchymal stromal cell treatment attenuates repetitive mild traumatic brain injury-induced persistent cognitive deficits via suppressing ferroptosis. J Neuroinflammation 2022;19:185. [PMID: 35836233 DOI: 10.1186/s12974-022-02550-7] [Reference Citation Analysis]
31 Tan LT, Phyo MY. Marine Cyanobacteria: A Source of Lead Compounds and their Clinically-Relevant Molecular Targets. Molecules 2020;25:E2197. [PMID: 32397127 DOI: 10.3390/molecules25092197] [Cited by in Crossref: 11] [Cited by in F6Publishing: 10] [Article Influence: 5.5] [Reference Citation Analysis]
32 Hosseini S, Pourmousavi SA, Mahdavi M, Taslimi P. Synthesis, and in vitro biological evaluations of novel naphthoquinone conjugated to aryl triazole acetamide derivatives as potential anti-Alzheimer agents. Journal of Molecular Structure 2022;1255:132229. [DOI: 10.1016/j.molstruc.2021.132229] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
33 Adeowo FY, Ejalonibu MA, Elrashedy AA, Lawal MM, Kumalo HM. Multi-target approach for Alzheimer's disease treatment: computational biomolecular modeling of cholinesterase enzymes with a novel 4-N-phenylaminoquinoline derivative reveal promising potentials. J Biomol Struct Dyn 2021;39:3825-41. [PMID: 33030113 DOI: 10.1080/07391102.2020.1826129] [Cited by in Crossref: 4] [Article Influence: 2.0] [Reference Citation Analysis]
34 Matos MJ. Multitarget therapeutic approaches for Alzheimer's and Parkinson's diseases: an opportunity or an illusion? Future Med Chem 2021;13:1301-9. [PMID: 34137271 DOI: 10.4155/fmc-2021-0119] [Reference Citation Analysis]