Curriculum Vitae    Personal data Name: Salah Mohamed El Sayed Date & place of birth: 21-7-1977 Fazara – Maragha – Sohag, Egypt Qualification: PhD in pediatric cancer gene therapy, Tokushima University, Japan in 2012 Marital status: Married to Dr Manal Nabo (PhD in pediatric cardiology in 2012) and having 6 kids. Current address: Saudi Arabia, Medina  Email addresses: salahfazara@yahoo.com, smemohamed@taibahu.edu.sa Scientific qualifications 1. September 1995: Joining Sohag Faculty of Medicine as a medical student. 2. September 2001: Bachelor degree of medicine and surgery (Sohag Faculty of Medicine, Sohag University, Egypt). 3. October 2005: Diploma degree in pediatrics, Ain Shams Faculty of Medicine, Ain Shams University, Egypt. 3. October 2006: Master degree in Medical Biochemistry (Sohag Faculty of Medicine, Sohag University, Egypt) 4. April 2012: Doctor degree (Ph.D) in cancer gene therapy (Department of Pediatrics, Tokushima University, Japan) in research collaboration with Institute for Enzyme Research (Medical Biochemistry, The University of Tokushima, Japan).   Clinical and laboratory skills development: March 2002-February 2003: A trainee physician in Sohag Faculty of Medicine University hospitals, Sohag, Egypt. March 2003-December 2007: A general practitioner and pediatrician in some private hospitals, Sohag, Egypt. March 2003-December 2007: A clinical chemistry and laboratory medicine teacher in Sohag Faculty of Medicine, Sohag University, Egypt. January 2008-April 2012: A clinical trainee graduate student and received 4 years of clinical training in pediatrics for PhD in cancer gene therapy, Department of Pediatrics, Tokushima University, Japan. January 2008-April 2012: A research trainee graduate student for PhD in cancer gene therapy in collaboration with Institute for Enzyme Research (Medical Biochemistry, The University of Tokushima, Japan). April 2012 –Now: Lecturer of clinical chemistry and laboratory medicine Sohag Faculty of Medicine, Sohag University, Egypt. February 2014 –September 2019: Assistant professor and physician in Taibah College of Medicine practicing and teaching medical students the following: -Medical genetics -Medical Nutrition -Laboratory medicine and clinical laboratory skills. -Integrative and prophetic medicine. -Medical and clinical chemistry. October 2019 – Now: Associate professor and physician in Taibah College of Medicine practicing and teaching medical students the following: -Practicing and teaching medical students the following: -Medical genetics -Medical Nutrition -Laboratory medicine and clinical laboratory skills. -Integrative and prophetic medicine. -Medical and clinical chemistry.   Jobs and Professional development 1. March 2002 – February 2003: Internship in medicine and surgery (Sohag University Hospital, Sohag Faculty of Medicine, Sohag University, Egypt) 2. May 2003 - October 2006: Demonstrator in Medical Biochemistry (Department of Medical Biochemistry, Sohag Faculty of Medicine, Sohag University, Egypt). 3. January 2008 - April 2012: PhD study in Pediatric department (in research collaboration with Institute for Enzyme Research at Medical Biochemistry, The University of Tokushima, Japan) for gaining doctor degree in cancer gene therapy Ph.D student (Tokushima Faculty of Medicine, The University of Tokushima, Japan). Assistant lecturer in Medical Biochemistry (Department of Medical Biochemistry, Sohag Faculty of Medicine, Sohag University, Egypt) 4. January 2013 - Today: Lecturer in Medical Biochemistry (Department of Medical Biochemistry, Sohag Faculty of Medicine, Sohag University, Egypt) 5. March 2014 – September 2019: Assistant professor in Medical Biochemistry and prophetic medicine (Department of Medical Biochemistry, Taibah College of Medicine, Taibah University in Saudi Arabia and Sohag University in Egypt). Acquired clinical skills: 1. Patients' reassurance, friendly dealing and amusement. 2. Clinical history taking 3. Clinical detailed medical examination. 4. Drug prescription and monitoring. 5. Patients' follow up and counselling. 6. Caring patients with special needs e.g. bed ridden patients. 7. Urgent patients manipulations e.g. catheters, ryle tubes, venous cannulas, respiratory suctions, …. 8. Excellent intercollege relationship and work co-operation. 9. Honestly keeping patients' privacy, secrecy and confidentiality. 10. Teaching the geniors and enhancing their skills, esteem and capabilities.                              Clinical research interest 1. Enhancing nutritional treatments for cancer patients e.g. breast cancer. 2. Enhancing antioxidant tissue-protective and rescue effects for minimizing chemotherapy and radiotherapy-related tissue damage. 3. Adjusting medical oncology adjuvant treatments to counteract cancer biology e.g. decreasing sugar intake to exhaust cancer cells (preventing glycolysis). 4. Improving treatment options for late-stage cancer patients e.g. treating malignant cachexia with patient motivation, psychotherapy and medical nutrition. 5. Trying to optimize the best protocols for cancer patients treatment based on our future experience and published cancer centers experience. 6. Making multicenter clinical research collaboration with other Canadian cancer centers whenever possible. 7. Attending as much cancer conferences as possible for better clinical experience and research collaboration. 8.Teaching the geniors the clinical skills and practice cues and publishing at least one textbook in clinical oncology practice and treatment.   List of publications 1. El Sayed SM. Enhancing anticancer effects, decreasing risks and solving practical problems facing 3-bromopyruvate in clinical oncology: 10 years of research experience. Int J Nanomedicine. 2018 Aug 15;13:4699-4709 2. El Sayed SM, Baghdadi H, Zolaly M, Almaramhy HH, Ayat M, Donki JG. The promising anticancer drug 3-bromopyruvate is metabolized through glutathione conjugation which affects chemoresistance and clinical practice: An evidence-based view. Med Hypotheses. 2017 Mar;100:67-77. 3. El Sayed SM, El-Magd RM, Shishido Y, Yorita K, Chung SP, Tran DH, Sakai T, Watanabe H, Kagami S, Fukui K. D-Amino acid oxidase-induced oxidative stress, 3-bromopyruvate and citrate inhibit angiogenesis, exhibiting potent anticancer effects. J Bioenerg Biomembr. 2012 Oct;44(5):513-23. 4. El Sayed SM, El-Magd RM, Shishido Y, Chung SP, Diem TH, Sakai T, Watanabe H, Kagami S, Fukui K. 3-Bromopyruvate antagonizes effects of lactate and pyruvate, synergizes with citrate and exerts novel anti-glioma effects. J Bioenerg Biomembr. 2012 Feb;44(1):61-79. 5. Nakano A, Tsuji D, Miki H, Cui Q, El Sayed SM, Ikegame A, Oda A, Amou H, Nakamura S, Harada T, Fujii S, Kagawa K, Takeuchi K, Sakai A, Ozaki S, Okano K, Nakamura T, Itoh K, Matsumoto T, Abe M. Glycolysis inhibition inactivates ABC transporters to restore drug sensitivity in malignant cells. PLoS One. 2011;6(11):e27222. 6.El Sayed SM, Abou El-Magd RM, Shishido Y, Chung SP, Sakai T, Watanabe H, Kagami S, Fukui K. D-amino acid oxidase gene therapy sensitizes glioma cells to the antiglycolytic effect of 3-bromopyruvate. Cancer Gene Ther. 2012 Jan;19(1):1-18. 7.Baghdadi H, Abdel-Aziz N, Ahmed NS, Mahmoud HS, Barghash A, Nasrat A, Nabo MM, El Sayed SM. Ameliorating Role Exerted by Al-Hijamah in Autoimmune Diseases: Effect on Serum Autoantibodies and Inflammatory Mediators. Int J Health Sci (Qassim). 2015 Apr;9(2):207-32. Review 8. Salah Mohamed El Sayed. Oxidative Stress Therapy for Cancer Using Glycolysis Inhibitors: Towards Improving Therapeutic Outcomes. American Journal of Medical and Biological Research, 2018, Vol. 6, No. 1, 11-15 9. El Sayed SM, Baghdadi H, Abou-Taleb A, Mahmoud HS, Maria RA, Ahmed NS, Helmy Nabo MM. Al-hijamah and oral honey for treating thalassemia, conditions of iron overload, and hyperferremia: toward improving the therapeutic outcomes. J Blood Med. 2014 Oct 30;5:219-37. doi: 10.2147/JBM.S65042. eCollection 2014. Review. 10. El Sayed SM, Abou-Taleb A, Mahmoud HS, Baghdadi H, Maria RA, Ahmed NS, Nabo MM. Percutaneous excretion of iron and ferritin (through Al-hijamah) as a novel treatment for iron overload in beta-thalassemia major, hemochromatosis and sideroblastic anemia. Med Hypotheses. 2014 Aug;83(2):238-46. 11. El Sayed SM, Mahmoud HS, Nabo MMH. Methods of Wet Cupping Therapy (Al-hijamah): In Light of Modern Medicine and Prophetic Medicine. Altern Integ Med. 2013;2:1–16. 12. El Sayed SM, Mahmoud HS, Nabo MMH. Medical and scientific bases of wet cupping therapy (Al-hijamah): in light of modern medicine and prophetic medicine. Altern Integ Med. 2013;2(3):1–16. 13. El Sayed SM, Al-quliti A, Mahmoud HS, Nabo MMH.  Therapeutic benefits of Al-hijamah: in light of modern medicine and prophetic medicine. AJMBR. 2(2):46–71. 14. Mahmoud HS, Abou-El-Naga M, Omar NAA, El-Ghazzawy HA, Fathy YM, Nabo MMH, Salah Mohamed El Sayed.. Anatomical sites for practicing Wet Cupping Therapy (Al-Hijamah): In Light of Modern Medicine and Prophetic Medicine. Altern Integ Med. 2013;2(8):1–30. 15. El Sayed SM, Mohamed WG, Seddik MA, Ahmed AS, Mahmoud AG, Amer WH, Helmy Nabo MM, Hamed AR, Ahmed NS, Abd-Allah AA. Safety and outcome of treatment of metastatic melanoma using 3-bromopyruvate: a concise literature review and case study. Chin J Cancer. 2014 Jul;33(7):356-64. 16. El Sayed SM, Mahmoud AA, El Sawy SA, Abdelaal EA, Fouad AM, Yousif RS, Hashim MS, Hemdan SB, Kadry ZM, Abdelmoaty MA, Gabr AG, Omran FM, Nabo MM, Ahmed NS. Warburg effect increases steady-state ROS condition in cancer cells through decreasing their antioxidant capacities (anticancer effects of 3-bromopyruvate through antagonizing Warburg effect). Med Hypotheses. 2013 Nov;81(5):866-70. 17.Nassar Ayoub Abdellatif Omar, Amal Nor Edeen Ahmad Allithy, Hussam Baghdadi, Mohammed Zolaly, Mohamed Abdel-haleem, Manal Mohamed Helmy, Mongi Mohamed Ahmed Ayat,  Salah Mohamed El Sayed. Hepatoprotective Effects Exerted by Propolis against Doxorubicin-induced Rat Liver Toxicity: A Biochemical and Histopathological Study. American Journal of Cancer Prevention, 2016, Vol. 4, No. 3, 36-40 18. Nassar A. A. Omar, Momen Elshazley, , Salah M. El Sayed, Amal N. A. Al- lithy, Manal Mohamed Helmy Nabo. Impact of Body Mass Index Changes on Development of Hypertension in Preparatory School Students: A Cross Sectional Study Based on Anthropometric Measurements.  American Journal of Medical and Biological Research, 2017, Vol. 5, No. 2, 31-37 19.Reham A. Mariah, Hussam Baghdadi, Kamal El-din Ahmed, Naglaa Mostafa,  Mongi Mohamed Ahmed Ayat1, Tayseer Nansour, Manal Mohamed Helmy Nabo,  Salah Mohamed El Sayed. Nassar Ayoub Abdellatif Omar. Frequency of Estrogen Receptor-1 (ESR-1) Gene Polymorphism (PvuII and XbaI) in Patients with Coronary Artery Disease. American Journal of Medical and Biological Research, 2016, Vol. 4, No. 1, 5-9    20. Mohamed El-Shanshory, Nahed Mohammed Hablas, Yasmin Shebel, Ahmed Ragab Fakhreldin, Mohammed Attia, Hamdi H. Almaramhy, Hussam Baghdadi6, Mongi Ayat1, Amal El-Baihany, Amr El-Dardear, Hoda Ali Ibrahim, Hany Salah Mahmoud, Manal Mohamed Helmy Nabo, Salah Mohamed El Sayed. The effects of Al-hijamah on reducing iron overload and oxidative stress in thalassaemic pediatric patients: A pilot study. Journal of Blood Medicine. J Blood Med. 2018 Dec 14;9:241-251 21. Hamouda O, Sweilam M, Abdellah A, El Sayed SM. Evaluation of pioneering introduction of integrative and prophetic medicine education in an Arabic medical school (Taibah University, Saudi Arabia): 10 years' experience. J Int Med Res. 2019 May;47(5):2157-2165. 22. Mohamed El-Shanshory, Nahed Mohammed  Hablas, Hamdi H. Almaramhy, Mohammed Attiad , Walaa Arafae, Reham A. Mariah, Hussam Baghdadi,   Mongi Ayata, Mohammed Zolaly, Manal Mohamed Helmy Nabo, Ahmed Alamir Mahmoud, Samer Ahmed El-Sawy, Mohamed Ismailj Mona Zidan,Momen Elshazley, Rami Alharbi, Sayed Moustafa , Mostafa A.M. Abouelnaga, Ahmed R Fakhreldin, Salah Mohamed El Sayed. Nigella sativa improves anemia, enhances immunity and relieves iron overload-induced oxidative stress as a promising treatment in children having beta-thalassemia major. Journal of Herbal Medicine. In press 23.Salah Mohamed El Sayed,  Hussam Baghdadi,  Nagwa Sayed Ahmed,  Hamdi H. Almaramhy,  Ahmed Al-Amir Mahmoud, Samer El-Sawy, MongiAyat, Momen Elshazley,   Wafaa Abdel-Aziz, Haitham Mahmoud Abdel-Latif,  Walaa Ibrahim. Dichloroacetate is an antimetabolite that antagonizes acetate and deprives cancer cells from its benefits: a novel evidence-based medical hypothesis. Med Hypotheses. In press. 24. Osama Hamouda, , Mohammad Sweilam3, Antar Abdellah, Moutasem Salih Aboonq, Osama Bashir Abdel-Halim, Salah Mohamed El Sayed and Ahmed Osama Hamouda. Outcome and Future Perspectives of Pioneering Integrative Medicine Education in Taibah University: Ten Years' Experience in Saudi Arabia Medical Schools (A Medical Education Article). American Journal of Educational Research. 2019, 7(1), 69-75 25. Salah Mohamed El Sayed1, 2, , Hussam Baghdadi1, Faten M. Omran3, Ahmed M. Okashah4, Samer A. El-Sawy2, Hytham Mahmoud1, Wafaa A. Abdellah3, Azza Mahmoud Ahmed Abouelela3, Hassan El-Alaf5, Elussainy MA Elussainy6, Sayed Mostafa El Sayed7, 8, Hesham I. Abdallah7, 8, Osama Al-hadramy9, Tamer M. Soliman10, Amr El-Dardear11, Mohamed Abdel-haleem12 and Manal M.H. Nabo13. Glioma Spheroid Cells (3D Tumor Models) Are Less Responsive to 3-Bromopyruvate than Cultured Cells: Lack of Tumors Eradication. American Journal of Cancer Prevention. 2019, 7(1), 10-14. 26. Amr El-Dardear1, Elsayed Abdelkreem2, Hussam Baghdadi3, Naif Aljuhani4, Osama Alhadramy5, Mohammed Hassan2, Faten M. Omran6, Hytham Mahmoud Abdel-Latif6, Wafaa A. Abdellah6, Azza Mahmoud Ahmed Abouelella6, Mohamed Abdel-haleem7, Momen El-shazley8, 9, Manal Mohamed Helmy Nabo10 and Salah Mohamed El Sayed3, 11 Dichloroacetate is Cardiotonic and Suggested for Treating Metabolic Acidosis: Alleviating Lactate Effects and Beta-ketothiolase Deficiency (An Original Article). American Journal of Medical Sciences and Medicine. 2020, 8(1), 1-5. 27. Salah Mohamed El Sayed , Elsayed Abdelkreem, Moutasem Salih Aboonq, Sultan S. Al Thagfan, Yaser M. Alahmadi, Osama Alhadramy, Hussam Baghdadi, Mohammed Hassan, Faten M. Omran, Hytham Mahmoud Abdel-Latif, Wafaa Abdel-ziz, Azza Mahmoud Ahmed Abouelella, Amr El-Dardear, Mohamed Abdel-haleem, Elhussainy MA Elhussainy, Hassan El-Alaf, Manal Mohamed Helmy Nabo. Dichloroacetate is a Novel Safe Treatment for Beta-ketothiolase Deficiency: Towards Better Therapeutic Outcomes (An Original Article). International Journal of Clinical and Experimental Neurology. 2020, 8(1), 4-8. DOI: 10.12691/ijcen-8-1-2   28. Hany Salah Mahmoud, Rehab A. Eltahlawi, Osama Alhadramy, Tamer M. Soliman, Yasser Mohamed FathyEl-Kot, Nassar Ayoub Abdellatif Omar, Sayed Mostafa El Sayed, Hesham I. Abdallah, Momen El-shazley, Amal Nor Edeen Ahmad Allithy, Noha El-Dabie, Mohamed Abdel-Haleem, Amr El-Dardear, Shaima Mohamed Abdelfattah Hassan, Manal Mohamed Helmy, Hassan El-Alaf, Hussam Baghdadi, Samer El-Sawy, Salah Mohamed El Sayed . Zamzam Water is Pathogen-free, Cardioprotective and Tissue-protective: Relieving the BBC Concerns. American Journal of Clinical Medicine Research. 2020, 8(1), 5-12. DOI: 10.12691/ajcmr-8-1-2       29. Salah Mohamed El Sayed1, 2, , Hamdi H. Almaramhy3, Yasmeen Talal Aljehani4, Ahmed M. Okashah5, Mariam E. El-Anzi6, Mansour Barakah AlHarbi7, Rehab El-Tahlawi8, 9, Manal Mohamed Helmy Nabo10, Moutasem Salih Aboonq11, Osama Hamouda12 and Osama Alhadramy13.The Evidence-Based TaibUVID Nutritional Treatment for Minimizing COVID-19 Fatalities and Morbidity and eradicating COVID-19 pandemic: A novel Approach for Better Outcomes (A Treatment Protocol). American Journal of Public Health Research. 2020, 8(2), 54-60   30. Faten M. Omran1, Hussam Baghdadi2, Tamer M. Soliman3, Osama Alhadramy4, Momen El-shazley5, 6, Samer A. El-Sawy7, Hytham Mahmoud Abdel-Latif1, Wafaa A. Abdellah1, Azza Mahmoud Ahmed Abouelella1, Amr El-Dardear8, Mohamed Abdel-haleem9, Elhussainy MA Elhussainy10, Hassan El-Alaf11, Nassar Ayoub12, Sayed Mostafa El Sayed13, 14, Hesham I. Abdallah13, 14, Salah Mohamed El Sayed2, 7, , Mongi Ayat15 and Ahmed Mohamed Shehata16, 17 Pharmacological Double Inhibition of Glycolysis in glioblastoma Multiforme Cells Maximizes Cancer Cell Killing: A Synergism between Citrate and 3-bromopyruvate. American Journal of Pharmacological Sciences. 2020, 8(1), 1-6   31. El-Shanshory M, Hablas NM, Shebel Y, Alhadramy O, El-Tahlawi R, Aboonq MS, Soliman TM, Abdel-Gawad AR, El Sayed SM, Abdallah HI, Mahmoud HS, El-Allaf H, El-Sawy S, Yousef RS, Abu-El Naga M, Mariah RA, Nabo MMH, Abdel-Haleem M, Mahmoud AA, Hassan MA, Al Arabi AH, Alnakhli AA, El Sayed SM. Al-hijamah (the triple S treatment of prophetic medicine) exerts cardioprotective, tissue-protective and immune potentiating effects in thalassemic children: a pilot clinical trial. Am J Blood Res. 2020 Dec 15;10(6):447-458.   32. El Sayed SM, Aboonq MS, Aljehani YT, Hassan MA, Abou El-Magd RM, Abdelrahman AI, El-Tahlawi R, Nabo MMH, Yousef RS, Mahmoud AA, Elsayed YY, Abu-Elnaga M, Soliman TM, Abdel-Gawad AR, Elshazley M, Baghdadi H, El-Sawy S, Mahmoud HS, El-Anzi ME, Alharbi MB. TaibUVID nutritional supplements help rapid cure of COVID-19 infection and rapid reversion to negative nasopharyngeal swab PCR: for better public prophylaxis and treatment of COVID-19 pandemic. Am J Blood Res. 2020 Dec 15;10(6):397-406.   33. Mahmoud HS, Eltahlawi RA, Jan AA, Alhadramy O, Soliman TM, El Sayed SM, Abdallah HI, El-Shazley M, Shafik NM, Mariah RA, El-Dabie N, Abdel-Haleem M, Hassan SMA, Nabo MMH, El-Alaf H, Baghdadi H, Yousef RS, Mahmoud AA, El Sayed SM, Amer SM. Zamzam water is pathogen-free, uricosuric, hypolipidemic and exerts tissue-protective effects: relieving BBC concerns. Am J Blood Res. 2020 Dec 15;10(6):386-396.   34. El Sayed SM, Aboonq MS, El Rashedy AG, Aljehani YT, Abou El-Magd RM, Okashah AM, El-Anzi ME, Alharbi MB, El-Tahlawi R, Nabo MMH, Yousef RS, Elshazley M, Abu-Elnaga M, Mahmoud HS, El-Alaf H, Abdelrahman AI, Abdel-Gawad AR, Soliman TM. Promising preventive and therapeutic effects of TaibUVID nutritional supplements for COVID-19 pandemic: towards better public prophylaxis and treatment (A retrospective study). Am J Blood Res. 2020 Oct 15;10(5):266-282. 35. Aljehani YT,  Alanzi ME, Aljehani ST, Saleem AS, Alraddadi SAR, Alblowi RM, Aly HY, El Sayed SM. Impact of pregnancy outcomes on postpartum depression among women attending primary health-care centers in Al-Madina Al-Munawarah, Saudi Arabia. Saudi Journal for Health Sciences - Volume 10, Issue 2, May-August 2021. 36. Aljehani YT, Alanzi ME, Aljehani ST, Alghamdi KS, ALHarthi NA, Alshareef A, El Sayed SM. Prevalence and factors associated with postpartum depression among women attending primary health care centers in Al‑Madina, Saudi Arabia. Res Psychol Behav Sci 2020;8:18‑24.   37. Mariah RM, El-Dardiry SA, Mahmoud HA, Mabrouk MM, El-Dardiry NA El Sayed SM. Effects of obesity-related inflammator,y markers on psychosomatic manifestations of premenstrual tension syndrome: towards better therapeutic outcomes. . (2022)SVU-IJMS 5:11-25.                       Under publication 1. Mohamed El-Shanshory, Nahed Mohammed  Hablas, Yasmin Shebel, Ahmed Ragab Fakhreldin, Mohammed Attia4 , Hamdi H. Almaramhy,  Hussam Baghdadi,   Mongi Ayat, Sayed Mostafa, Nassar Ayoub Omar, Reham Abdel-Salam Mariah, Mostafa Abu-el Naga, Manal Mohamed Helmy Nabo, Amr El-Dardear, Salah Mohamed El Sayed. Wet cupping therapy (Al-hijamah) is safe and promising in outpatient clinics medical practice, enhances immunity and exerts tissue-protective effects in thalassemic children: A pilot clinical trial. Journal of Research in Medical Sciences.   Conference proceedings 1. Speaker at: iCancer 2019, 3rd international Cancer Conference and EXPO, Baltimore, USA. 2. Annual meeting of D-amino acid oxidase society of Japan, March 2010, Kobe, Japan. 3. iCancer conference in Baltimore USA June 2nd to June 5th, 2019.