Copyright ©The Author(s) 2015.
World J Exp Med. May 20, 2015; 5(2): 50-63
Published online May 20, 2015. doi: 10.5493/wjem.v5.i2.50
Figure 2
Figure 2 Simplified scheme of the impaired immunity during sepsis and the potential use of biomarkers: Initially, the body reacts to infectious stimuli with a proinflammatory immune response. Simultaneously, compensatory mechanisms are initiated to counteract the inflammatory process. The resulting net immune suppression is characterised by an increased risk of opportunistic infections. Beside C-reactive protein and procalcitonin, further biomarkers may be used in diagnosis, therapy-guidance and outcome prediction of sepsis.