BPG is committed to discovery and dissemination of knowledge
High Impact Articles
High impact papers are those to which special attention is paid by experts in the given field, with a large number of visitors, frequent downloads and higher citation rates. The research must be creative, with high academic standards and have a wide influence, if it is to become a high impact paper. They are ranked by the number of downloads.
Rank Full Article
1
Cost effectiveness of intensive care in a low resource setting: A prospective cohort of medical critically ill patients  
Hajrunisa Cubro, Rabija Somun-Kapetanovic, Guillaume Thiery, Daniel Talmor, Ognjen Gajic 
World J Crit Care Med 5(2):150-164. Published online May 4, 2016. doi: 10.5492/wjccm.v5.i2.150
2
Efficacy of prone position in acute respiratory distress syndrome patients: A pathophysiology-based review  
Vasilios Koulouras, Georgios Papathanakos, Athanasios Papathanasiou, Georgios Nakos 
World J Crit Care Med 5(2):121-136. Published online May 4, 2016. doi: 10.5492/wjccm.v5.i2.121
3
Focus on peripherally inserted central catheters in critically ill patients  
Paolo Cotogni, Mauro Pittiruti 
World J Crit Care Med 3(4):80-94. Published online Nov 4, 2014. doi: 10.5492/wjccm.v3.i4.80
4
Prevention of stress-related ulcer bleeding at the intensive care unit: Risks and benefits of stress ulcer prophylaxis  
Lukas Buendgens, Alexander Koch, Frank Tacke 
World J Crit Care Med 5(1):57-64. Published online Feb 4, 2016. doi: 10.5492/wjccm.v5.i1.57
5
Use of venous-to-arterial carbon dioxide tension difference to guide resuscitation therapy in septic shock  
Jihad Mallat, Malcolm Lemyze, Laurent Tronchon, Benoît Vallet, Didier Thevenin 
World J Crit Care Med 5(1):47-56. Published online Feb 4, 2016. doi: 10.5492/wjccm.v5.i1.47
6
Intravenous vitamin C as adjunctive therapy for enterovirus/rhinovirus induced acute respiratory distress syndrome  
Alpha A Fowler III, Christin Kim, Lawrence Lepler, Rajiv Malhotra, Orlando Debesa, Ramesh Natarajan, Bernard J Fisher, Aamer Syed, Christine DeWilde, Anna Priday, Vigneshwar Kasirajan 
World J Crit Care Med 6(1):85-90. Published online Feb 4, 2017. doi: 10.5492/wjccm.v6.i1.85
7
8
Effects of intrapulmonary percussive ventilation on airway mucus clearance: A bench model  
Lorena Fernandez-Restrepo, Lauren Shaffer, Bravein Amalakuhan, Marcos I Restrepo, Jay Peters, Ruben Restrepo 
World J Crit Care Med 6(3):164-171. Published online Aug 4, 2017. doi: 10.5492/wjccm.v6.i3.164
9
Vitamin C in the critically ill - indications and controversies  
Christoph S Nabzdyk, Edward A Bittner 
World J Crit Care Med 7(5):52-61. Published online Oct 16, 2018. doi: 10.5492/wjccm.v7.i5.52
10
Recruitment maneuvers in acute respiratory distress syndrome: The safe way is the best way  
Raquel S Santos, Pedro L Silva, Paolo Pelosi, Patricia RM Rocco 
World J Crit Care Med 4(4):278-286. Published online Nov 4, 2015. doi: 10.5492/wjccm.v4.i4.278
11
Steps to consider in the approach and management of critically ill patient with spontaneous intracerebral hemorrhage  
Daniel Agustin Godoy, Gustavo Rene Piñero, Patricia Koller, Luca Masotti, Mario Di Napoli 
World J Crit Care Med 4(3):213-229. Published online Aug 4, 2015. doi: 10.5492/wjccm.v4.i3.213
12
Fluid and electrolyte overload in critically ill patients: An overview  
Bruno Adler Maccagnan Pinheiro Besen, André Luiz Nunes Gobatto, Lívia Maria Garcia Melro, Alexandre Toledo Maciel, Marcelo Park 
World J Crit Care Med 4(2):116-129. Published online May 4, 2015. doi: 10.5492/wjccm.v4.i2.116
13
Plasma-Lyte 148: A clinical review  
Laurence Weinberg, Neil Collins, Kiara Van Mourik, Chong Tan, Rinaldo Bellomo 
World J Crit Care Med 5(4):235-250. Published online Nov 4, 2016. doi: 10.5492/wjccm.v5.i4.235
14
Anticoagulant modulation of inflammation in severe sepsis  
Karen S Allen, Eva Sawheny, Gary T Kinasewitz 
World J Crit Care Med 4(2):105-115. Published online May 4, 2015. doi: 10.5492/wjccm.v4.i2.105
15
Severe trauma in the geriatric population  
Juan Antonio Llompart-Pou, Jon Pérez-Bárcena, Mario Chico-Fernández, Marcelino Sánchez-Casado, Joan Maria Raurich 
World J Crit Care Med 6(2):99-106. Published online May 4, 2017. doi: 10.5492/wjccm.v6.i2.99
16
Prognostic categorization of intensive care septic patients  
Mohamed Ezzat Moemen 
World J Crit Care Med 1(3):67-79. Published online Jun 4, 2012. doi: 10.5492/wjccm.v1.i3.67
17
18
Extracorporeal membrane oxygenation for pediatric respiratory failure: History, development and current status  
Anna Maslach-Hubbard, Susan L Bratton 
World J Crit Care Med 2(4):29-39. Published online Nov 4, 2013. doi: 10.5492/wjccm.v2.i4.29
19
Controversies in fluid therapy: Type, dose and toxicity  
Robert C McDermid, Karthik Raghunathan, Adam Romanovsky, Andrew D Shaw, Sean M Bagshaw 
World J Crit Care Med 3(1):24-33. Published online Feb 4, 2014. doi: 10.5492/wjccm.v3.i1.24
20
Tumor lysis syndrome: A clinical review  
Aibek E Mirrakhimov, Prakruthi Voore, Maliha Khan, Alaa M Ali 
World J Crit Care Med 4(2):130-138. Published online May 4, 2015. doi: 10.5492/wjccm.v4.i2.130
21
Timing, method and discontinuation of hydrocortisone administration for septic shock patients  
Miguel A Ibarra-Estrada, Quetzalcóatl Chávez-Peña, Claudia I Reynoso-Estrella, Jorge Rios-Zermeño, Pável E Aguilera-González, Miguel A García-Soto, Guadalupe Aguirre-Avalos 
World J Crit Care Med 6(1):65-73. Published online Feb 4, 2017. doi: 10.5492/wjccm.v6.i1.65
22
Critical care management and intensive care unit outcomes following cytoreductive surgery with hyperthermic intraperitoneal chemotherapy  
Sumit Kapoor, Adel Bassily-Marcus, Rafael Alba Yunen, Parissa Tabrizian, Sabrine Semoin, Joseph Blankush, Daniel Labow, John Oropello, Anthony Manasia, Roopa Kohli-Seth 
World J Crit Care Med 6(2):116-123. Published online May 4, 2017. doi: 10.5492/wjccm.v6.i2.116
23
Characteristics of postintensive care syndrome in survivors of pediatric critical illness: A systematic review  
Elizabeth A Herrup, Beth Wieczorek, Sapna R Kudchadkar 
World J Crit Care Med 6(2):124-134. Published online May 4, 2017. doi: 10.5492/wjccm.v6.i2.124
24
Early debridement and delayed primary vascularized cover in forearm electrical burns: A prospective study  
Aniruddh Mene, Gautam Biswas, Atul Parashar, Anish Bhattacharya 
World J Crit Care Med 5(4):228-234. Published online Nov 4, 2016. doi: 10.5492/wjccm.v5.i4.228
25
Severe sepsis and septic shock in the elderly: An overview  
Prashant Nasa, Deven Juneja, Omender Singh 
World J Crit Care Med 1(1):23-30. Published online Feb 4, 2012. doi: 10.5492/wjccm.v1.i1.23
26
27
Invasive candidiasis in critical care setting, updated recommendations from “Invasive Fungal Infections-Clinical Forum”, Iran  
Ashraf Elhoufi, Arezoo Ahmadi, Amir Mohammad Hashem Asnaashari, Mohammad Ali Davarpanah, Behrooz Farzanegan Bidgoli, Omid Moradi Moghaddam, Mohammad Torabi-Nami, Saeed Abbasi, Malak El-Sobky, Ali Ghaziani, Mohammad Hossein Jarrahzadeh, Reza Shahrami, Farzad Shirazian, Farhad Soltani, Homeira Yazdinejad, Farid Zand 
World J Crit Care Med 3(4):102-112. Published online Nov 4, 2014. doi: 10.5492/wjccm.v3.i4.102
28
Implementation of enteral feeding protocol in an intensive care unit: Before-and-after study  
Martin Padar, Gerli Uusvel, Liis Starkopf, Joel Starkopf, Annika Reintam Blaser 
World J Crit Care Med 6(1):56-64. Published online Feb 4, 2017. doi: 10.5492/wjccm.v6.i1.56
29
Neuroprotective measures in children with traumatic brain injury  
Shruti Agrawal, Ricardo Garcia Branco 
World J Crit Care Med 5(1):36-46. Published online Feb 4, 2016. doi: 10.5492/wjccm.v5.i1.36
30
Brain-lung crosstalk: Implications for neurocritical care patients  
Ségolène Mrozek, Jean-Michel Constantin, Thomas Geeraerts 
World J Crit Care Med 4(3):163-178. Published online Aug 4, 2015. doi: 10.5492/wjccm.v4.i3.163
31
Clinical decision support for drug related events: Moving towards better prevention  
Sandra L Kane-Gill, Archita Achanta, John A Kellum, Steven M Handler 
World J Crit Care Med 5(4):204-211. Published online Nov 4, 2016. doi: 10.5492/wjccm.v5.i4.204
32
Iatrogenic pneumothorax related to mechanical ventilation  
Chien-Wei Hsu, Shu-Fen Sun 
World J Crit Care Med 3(1):8-14. Published online Feb 4, 2014. doi: 10.5492/wjccm.v3.i1.8
33
Modeling cardiac arrest and resuscitation in the domestic pig  
Brandon H Cherry, Anh Q Nguyen, Roger A Hollrah, Albert H Olivencia-Yurvati, Robert T Mallet 
World J Crit Care Med 4(1):1-12. Published online Feb 4, 2015. doi: 10.5492/wjccm.v4.i1.1
34
Clinical characteristics and outcomes associated with nasal intermittent mandatory ventilation in acute pediatric respiratory failure  
Billy C Wang, Theodore Pei, Cheryl B Lin, Rong Guo, David Elashoff, James A Lin, Carol Pineda 
World J Crit Care Med 7(4):46-51. Published online Sep 7, 2018. doi: 10.5492/wjccm.v7.i4.46
35
Optimizing the value of measuring inferior vena cava diameter in shocked patients  
Fikri M Abu-Zidan 
World J Crit Care Med 5(1):7-11. Published online Feb 4, 2016. doi: 10.5492/wjccm.v5.i1.7
36
Rhabdomyolysis, compartment syndrome and thermal injury  
Yusuf Kenan Coban 
World J Crit Care Med 3(1):1-7. Published online Feb 4, 2014. doi: 10.5492/wjccm.v3.i1.1
37
General anesthesia mediated by effects on ion channels  
Cheng Zhou, Jin Liu, Xiang-Dong Chen 
World J Crit Care Med 1(3):80-93. Published online Jun 4, 2012. doi: 10.5492/wjccm.v1.i3.80
38
Adverse events in critical care: Search and active detection through the Trigger Tool  
Francisco J Molina, Paula T Rivera, Alejandro Cardona, Diana C Restrepo, Oralia Monroy, Daniel Rodas, Juan G Barrientos 
World J Crit Care Med 7(1):9-15. Published online Feb 4, 2018. doi: 10.5492/wjccm.v7.i1.9
39
Severe scrub typhus infection: Clinical features, diagnostic challenges and management  
John Victor Peter, Thomas I Sudarsan, John Anthony J Prakash, George M Varghese 
World J Crit Care Med 4(3):244-250. Published online Aug 4, 2015. doi: 10.5492/wjccm.v4.i3.244
40
Deep sternal wound infection after cardiac surgery: Evidences and controversies  
Paolo Cotogni, Cristina Barbero, Mauro Rinaldi 
World J Crit Care Med 4(4):265-273. Published online Nov 4, 2015. doi: 10.5492/wjccm.v4.i4.265
41
Nutrient stimulation of mesenteric blood flow - implications for older critically ill patients  
Thu AN Nguyen, Yasmine Ali Abdelhamid, Liza K Phillips, Leeanne S Chapple, Michael Horowitz, Karen L Jones, Adam M Deane 
World J Crit Care Med 6(1):28-36. Published online Feb 4, 2017. doi: 10.5492/wjccm.v6.i1.28
42
Effects of mineralocorticoid receptor antagonists on responses to hemorrhagic shock in rats  
Kanako Yamamoto, Takashi Yamamoto, Masayuki Takamura, Soichiro Usui, Hisayoshi Murai, Shuichi Kaneko, Takumi Taniguchi 
World J Crit Care Med 7(1):1-8. Published online Feb 4, 2018. doi: 10.5492/wjccm.v7.i1.1
43
Enteral nutrition administration in a surgical intensive care unit: Achieving goals with better strategies  
Sara Wilson, Nagendra Y Madisi, Adel Bassily-Marcus, Anthony Manasia, John Oropello, Roopa Kohli-Seth 
World J Crit Care Med 5(3):180-186. Published online Aug 4, 2016. doi: 10.5492/wjccm.v5.i3.180
44
Female gonadal hormone effects on microglial activation and functional outcomes in a mouse model of moderate traumatic brain injury  
Odera Umeano, Haichen Wang, Hana Dawson, Beilei Lei, Afoma Umeano, Dawn Kernagis, Michael L James 
World J Crit Care Med 6(2):107-115. Published online May 4, 2017. doi: 10.5492/wjccm.v6.i2.107
45
Association between infections caused by multidrug-resistant gram-negative bacteria and mortality in critically ill patients  
Elisabeth Paramythiotou, Christina Routsi 
World J Crit Care Med 5(2):111-120. Published online May 4, 2016. doi: 10.5492/wjccm.v5.i2.111
46
Respiratory mechanics in brain injury: A review  
Antonia Koutsoukou, Maria Katsiari, Stylianos E Orfanos, Anastasia Kotanidou, Maria Daganou, Magdalini Kyriakopoulou, Nikolaos G Koulouris, Nikoletta Rovina 
World J Crit Care Med 5(1):65-73. Published online Feb 4, 2016. doi: 10.5492/wjccm.v5.i1.65
47
Preemptive mechanical ventilation can block progressive acute lung injury  
Benjamin Sadowitz, Sumeet Jain, Michaela Kollisch-Singule, Joshua Satalin, Penny Andrews, Nader Habashi, Louis A Gatto, Gary Nieman 
World J Crit Care Med 5(1):74-82. Published online Feb 4, 2016. doi: 10.5492/wjccm.v5.i1.74
48
Intensive care unit complications and outcomes of adult patients with hemophagocytic lymphohistiocytosis: A retrospective study of 16 cases  
Sumit Kapoor, Christopher K Morgan, Muhammad Asim Siddique, Kalpalatha K Guntupalli 
World J Crit Care Med 7(6):73-83. Published online Nov 30, 2018. doi: 10.5492/wjccm.v7.i6.73
49
Determination of functional prognosis in hospitalized patients following an intensive care admission  
Natália A Ferreira, Agnaldo José Lopes, Arthur S Ferreira, George Ntoumenopoulos, Jerffesson Dias, Fernando S Guimaraes 
World J Crit Care Med 5(4):219-227. Published online Nov 4, 2016. doi: 10.5492/wjccm.v5.i4.219
50
Hemolytic uremic syndrome in adults: A case report  
Fabiel Gerardo Pérez-Cruz, Patricia Villa-Díaz, María Consuelo Pintado-Delgado, María Loreto Fernández_Rodríguez, Ana Blasco-Martínez, María Pérez-Fernández 
World J Crit Care Med 6(2):135-139. Published online May 4, 2017. doi: 10.5492/wjccm.v6.i2.135