Dental pulp stem cells: Novel cell-based and cell-free therapy for peripheral nerve repair

Table 2 Studies retrieved from PubMed database evaluating the effect of DPSCs on nerve repair or regeneration in-vivo

Author	Publication year	Source of stem cells	Target nerves	Study model	Objective	Outcome
Ullah et al[82], 2017	2017	Human DPSCs; Differentiated neuronal cells from DPSCs	5-mm gap sciatic nerve transection	Animal rat model	To evaluate the in-vivo peripheral nerve regeneration potential of human DPSCs and differentiated neuronal cells from DPSCs.	In-vivo transplantation of the undifferentiated hDPSCs could exhibit sufficient and excellent peripheral nerve regeneration potential.
Spyridopoulos et al[83], 2015	2015	DPSCs isolated from second lateral incisor pigs	Transected fifth and sixth intercostal nerves	Animal pig model	Examined the potential of DPSCs for peripheral nerve regeneration, using biodegradable collagen conduits.	The nerves where DPSCs were injected exhibited morphological and functional recovery.

DPSCs: Dental pulp stem cells; hDPSCs: Human dental pulp stem cells.