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High Impact Articles
High impact papers are those to which special attention is paid by experts in the given field, with a large number of visitors, frequent downloads and higher citation rates. The research must be creative, with high academic standards and have a wide influence, if it is to become a high impact paper. They are ranked by the number of downloads.
Rank Full Article
1
A concise, practical guide to diagnostic assessment for mast cell activation disease  
Lawrence B Afrin, Gerhard J Molderings 
World J Hematol 3(1):1-17. Published online Feb 6, 2014. doi: 10.5315/wjh.v3.i1.1
2
Granulysin and its clinical significance as a biomarker of immune response and NK cell related neoplasms  
Masayuki Nagasawa, Kazuyuki Ogawa, Kinya Nagata, Norio Shimizu 
World J Hematol 3(4):128-137. Published online Nov 6, 2014. doi: 10.5315/wjh.v3.i4.128
3
Treatment of Epstein-Barr virus-related hemophagocytic lymphohistiocytosis: Study protocol of a prospective pilot study  
Shinsaku Imashuku 
World J Hematol 4(4):69-75. Published online Nov 6, 2015. doi: 10.5315/wjh.v4.i4.69
4
Another look at the life of a neutrophil  
Siroon Bekkering, Ruurd Torensma 
World J Hematol 2(2):44-58. Published online May 6, 2013. doi: 10.5315/wjh.v2.i2.44
5
6
Current approach to disseminated intravascular coagulation related to sepsis - organ failure type  
Jose J Zaragoza, Missael V Espinoza-Villafuerte 
World J Hematol 6(1):11-16. Published online Feb 6, 2017. doi: 10.5315/wjh.v6.i1.11
7
European vs 2015-World Health Organization clinical molecular and pathological classification of myeloproliferative neoplasms  
Jan Jacques Michiels, Fransje Valster, Jenne Wielenga, Katrien Schelfout, Hendrik De Raeve 
World J Hematol 4(3):16-53. Published online Aug 6, 2015. doi: 10.5315/wjh.v4.i3.16
8
Follicular helper T lymphocytes in health and disease  
Cecilia Parodi, María Noel Badano, Nora Galassi, Ana Coraglia, Patricia Baré, Alejandro Malbrán, María Marta de Elizalde de Bracco 
World J Hematol 3(4):118-127. Published online Nov 6, 2014. doi: 10.5315/wjh.v3.i4.118
9
10
Aspirin responsive platelet thrombophilia in essential thrombocythemia and polycythemia vera  
Jan Jacques Michiels, Fibo WJ Ten Kate, Peter J Koudstaal, Perry JJ Van Genderen 
World J Hematol 2(2):20-43. Published online May 6, 2013. doi: 10.5315/wjh.v2.i2.20
11
Role of novel oral anticoagulants in the management and prevention of venous thromboembolism  
Helen E Jo, David J Barnes 
World J Hematol 4(1):1-9. Published online Feb 6, 2015. doi: 10.5315/wjh.v4.i1.1
12
Storage lesion: History and perspectives  
Julien Delobel, Olivier Garraud, Stefano Barelli, Jean-Jacques Lefrère, Michel Prudent, Niels Lion, Jean-Daniel Tissot 
World J Hematol 4(4):54-68. Published online Nov 6, 2015. doi: 10.5315/wjh.v4.i4.54
13
Changing insights in the diagnosis and classification of autosomal recessive and dominant von Willebrand diseases 1980-2015  
Jan Jacques Michiels, Angelika Batorova, Tatiana Prigancova, Petr Smejkal, Miroslav Penka, Inge Vangenechten, Alain Gadisseur 
World J Hematol 5(3):61-74. Published online Aug 6, 2016. doi: 10.5315/wjh.v5.i3.61
14
PVSG and WHO vs European Clinical, Molecular and Pathological Criteria for prefibrotic myeloproliferative neoplasms  
Jan Jacques Michiels, Zwi Berneman, Wilfried Schroyens, King H Lam, Hendrik De Raeve 
World J Hematol 2(3):71-88. Published online Aug 6, 2013. doi: 10.5315/wjh.v2.i3.71
15
Aspirin cures erythromelalgia and cerebrovascular disturbances in JAK2-thrombocythemia through platelet-cycloxygenase inhibition  
Jan Jacques Michiels 
World J Hematol 6(3):32-54. Published online Aug 6, 2017. doi: 10.5315/wjh.v6.i3.32
16
Management of adult Langerhans cell histiocytosis based on the characteristic clinical features  
Shinsaku Imashuku, Chihiro Shimazaki, Arinobu Tojo, Toshihiko Imamura, Akira Morimoto 
World J Hematol 2(3):89-98. Published online Aug 6, 2013. doi: 10.5315/wjh.v2.i3.89
17
Clinical approach to diarrheal disorders in allogeneic hematopoietic stem cell transplant recipients  
Shadi Hamdeh, Abd Almonem M Abdelrahman, Osama Elsallabi, Ranjan Pathak, Smith Giri, Kailash Mosalpuria, Vijaya Raj Bhatt 
World J Hematol 5(1):23-30. Published online Feb 6, 2016. doi: 10.5315/wjh.v5.i1.23
18
Intestinal heme absorption in hemochromatosis gene knock-out mice  
Abas H Laftah, Robert J Simpson, Gladys O Latunde-Dada 
World J Hematol 6(1):17-23. Published online Feb 6, 2017. doi: 10.5315/wjh.v6.i1.17
19
Retrospective study of a cohort of adult patients with hematological malignancies in a tropical area  
Jean-Pierre Droz, Laure Bianco, Béatrice Cenciu, Maïa Forgues, Florin Santa, Jérome Fayette, Pierre Couppié 
World J Hematol 5(1):37-50. Published online Feb 6, 2016. doi: 10.5315/wjh.v5.i1.37
20
Hemophagocytic lymphohistiocytosis: Recent progress in the pathogenesis, diagnosis and treatment  
Shinsaku Imashuku 
World J Hematol 3(3):71-84. Published online Aug 6, 2014. doi: 10.5315/wjh.v3.i3.71
21
Management of unstable angina in a patient with Haemophilia A  
Andreina Carbone, Tiziana Formisano, Francesco Natale, Maurizio Cappelli Bigazzi, Donato Tartaglione, Enrica Golia, Felice Gragnano, Mario Crisci, Renato Maria Bianchi, Raffaele Calabrò, Maria Giovanna Russo, Paolo Calabrò 
World J Hematol 6(2):28-31. Published online May 6, 2017. doi: 10.5315/wjh.v6.i2.28
22
Role of microRNA in regulation of myeloma-related angiogenesis and survival  
Michal A Rahat, Meir Preis 
World J Hematol 5(2):51-60. Published online May 6, 2016. doi: 10.5315/wjh.v5.i2.51
23
Role of plasmapheresis in early allograft dysfunction following deceased donor liver transplantation  
Ashwin Rammohan, Deepti Sachan, Satish Logidasan, Jeswanth Sathyanesan, Ravichandran Palaniappan, Mohamed Rela 
World J Hematol 6(1):24-27. Published online Feb 6, 2017. doi: 10.5315/wjh.v6.i1.24
24
Oxidative alterations in sickle cell disease: Possible involvement in disease pathogenesis  
Yesim Oztas, Ahmet Yalcinkaya 
World J Hematol 6(3):55-61. Published online Aug 6, 2017. doi: 10.5315/wjh.v6.i3.55
25
Advances and perspectives on cellular therapy in acquired bone marrow failure diseases  
Xiao-Shen Sun, Xin Liu, Kai-Lin Xu, Allshine Chen, Witold B Rybka, Jeffrey J Pu 
World J Hematol 5(1):31-36. Published online Feb 6, 2016. doi: 10.5315/wjh.v5.i1.31
26
Intravascular proliferating anaplastic lymphoma kinase-positive anaplastic large-cell lymphoma  
Kohei Shiroshita, Jun-ichiro Kida, Kensuke Matsumoto, Makiko Uemura, Genji Yamaoka, Yumi Miyai, Reiji Haba, Osamu Imataki 
World J Hematol 4(2):10-15. Published online May 6, 2015. doi: 10.5315/wjh.v4.i2.10
27
Myelofibrosis: Prognostication and cytoreductive treatment  
Margherita Maffioli, Domenica Caramazza, Barbara Mora, Michele Merli, Francesco Passamonti 
World J Hematol 3(3):85-92. Published online Aug 6, 2014. doi: 10.5315/wjh.v3.i3.85
28
Insights into myelodysplastic syndromes from current preclinical models  
Shuh Ying Tan, Monique F Smeets, Alistair M Chalk, Harshal Nandurkar, Carl R Walkley, Louise E Purton, Meaghan Wall 
World J Hematol 5(1):1-22. Published online Feb 6, 2016. doi: 10.5315/wjh.v5.i1.1
29
Allogeneic stem cell transplantation in chronic myeloid leukemia patients: Single center experience  
Nur Soyer, Ayse Uysal, Murat Tombuloglu, Fahri Sahin, Guray Saydam, Filiz Vural 
World J Hematol 6(1):1-10. Published online Feb 6, 2017. doi: 10.5315/wjh.v6.i1.1
30
Unusual cytogenetic abnormalities associated with Philadelphia chromosome  
Sanjeev Kumar Sharma, Anil Handoo, Dharma Choudhary, Nitin Gupta 
World J Hematol 3(3):115-117. Published online Aug 6, 2014. doi: 10.5315/wjh.v3.i3.115
31
Anti-CD20 monoclonal antibodies and associated viral hepatitis in hematological diseases  
Shih-Hung Yang, Chiun Hsu, Ann-Lii Cheng, Sung-Hsin Kuo 
World J Hematol 3(2):29-43. Published online May 6, 2014. doi: 10.5315/wjh.v3.i2.29
32
Pseudohemophilia of Erik von Willebrand caused by homozygous one nucleotide deletion in exon 18 of the VW-factor gene  
Alain Gadisseur, Zwi Berneman, Wilfried Schroyens, Jan Jacques Michiels 
World J Hematol 2(4):99-108. Published online Nov 6, 2013. doi: 10.5315/wjh.v2.i4.99
33
P2X7 receptor activation causes phosphatidylserine exposure in canine erythrocytes  
Megan Faulks, Tracey A Kuit, Reece A Sophocleous, Belinda L Curtis, Stephen J Curtis, Lisa M Jurak, Ronald Sluyter 
World J Hematol 5(4):88-93. Published online Nov 6, 2016. doi: 10.5315/wjh.v5.i4.88
34
Cost of allogeneic blood transfusion  
Diana Sun, Ivo Abraham 
World J Hematol 1(3):8-13. Published online Oct 6, 2012. doi: 10.5315/wjh.v1.i3.8
35
Blood groups, hemoglobin phenotypes and clinical disorders of consanguineous Yansi population  
Nana Munlemvo Mavanga, François Boemer, Laurence Seidel, André Nkebolo Malafu, André Gothot, Christiane Gerard 
World J Hematol 2(4):109-114. Published online Nov 6, 2013. doi: 10.5315/wjh.v2.i4.109
36
Identifying changes in punitive transcriptional factor binding sites from regulatory single nucleotide polymorphisms that are significantly associated with disease or sickness  
Norman E Buroker 
World J Hematol 5(4):75-87. Published online Nov 6, 2016. doi: 10.5315/wjh.v5.i4.75
37
Age is an independent adverse prognostic factor for overall survival in acute myeloid leukemia in Japan  
Hiroaki Ohnishi, Osamu Imataki, Yasunori Kawachi, Makoto Ide, Kimihiro Kawakami, Masato Waki, Hidetaka Takimoto, Yasuo Hoshijima, Tetsuya Fukumoto, Kensuke Matsumoto, Fusako Waki, Akihito Matsuoka, Takamichi Shintani, Makiko Uemura, Shigeyuki Yokokura, Teruhisa Taoka, Takuya Matsunaga 
World J Hematol 3(3):105-114. Published online Aug 6, 2014. doi: 10.5315/wjh.v3.i3.105
38
Contribution of new immunoglobulin-derived biomarkers in plasma cell dyscrasias and lymphoproliferative disorders  
Marie-Christine Kyrtsonis, Dimitrios Maltezas, Efstathios Koulieris, Tatiana Tzenou, Stephen J Harding 
World J Hematol 2(2):6-12. Published online May 6, 2013. doi: 10.5315/wjh.v2.i2.6
39
Chronic disseminated candidiasis complicated with a ruptured intracranial fungal aneurysm in ALL  
Teppei Okawa, Toshiaki Ono, Akifumi Endo, Masatoshi Takagi, Masayuki Nagasawa 
World J Hematol 3(2):44-48. Published online May 6, 2014. doi: 10.5315/wjh.v3.i2.44
40
Ex vivo expansion of hematopoietic stem and progenitor cells: Recent advances  
Katsuhiro Kita, Fangming Xiu, Marc G Jeschke 
World J Hematol 3(2):18-28. Published online May 6, 2014. doi: 10.5315/wjh.v3.i2.18
41
Tbl3 encodes a WD40 nucleolar protein with regulatory roles in ribosome biogenesis  
Jindong Wang, Schickwann Tsai 
World J Hematol 3(3):93-104. Published online Aug 6, 2014. doi: 10.5315/wjh.v3.i3.93
42
Successful lower leg microsurgical reconstruction in homozygous sickle cell disease: Case report  
Carolina Posso, Francisco Cuéllar-Ambrosi 
World J Hematol 5(4):94-98. Published online Nov 6, 2016. doi: 10.5315/wjh.v5.i4.94
43
Autologous lymphocytes infusion  
Luis F Porrata, Svetomir N Markovic 
World J Hematol 2(2):59-61. Published online May 6, 2013. doi: 10.5315/wjh.v2.i2.59
44
Circulating microparticles and microRNAs as players in atherosclerosis  
Nicoleta Alexandru, Adriana Georgescu 
World J Hematol 2(2):16-19. Published online May 6, 2013. doi: 10.5315/wjh.v2.i2.16
45
Emerging immunological concepts in the pathogenesis of myelodysplastic syndromes  
Claudio Fozza 
World J Hematol 2(2):13-15. Published online May 6, 2013. doi: 10.5315/wjh.v2.i2.13
46
MGUS: Proposal for outpatient management  
Paolo Savini, Giorgio Marano, Arianna Lanzi, Barbara Castagnari, Giuseppe Musardo, Annalia Molinari, Claudia Cellini, Giuseppe Francesco Stefanini 
World J Hematol 1(2):5-7. Published online Aug 6, 2012. doi: 10.5315/wjh.v1.i2.5
47
Gemcitabine cures metastatic hepatic carcinoma and bone metastasis  
Chih-Chao Yang, Wai-Kevng Chow, Yen-Chun Peng, Ran-Ching Wang 
World J Hematol 2(4):115-118. Published online Nov 6, 2013. doi: 10.5315/wjh.v2.i4.115
48
An exciting time to launch the World Journal of Hematology  
Xiaoyan Jiang 
World J Hematol 1(1):1-4. Published online Jun 6, 2012. doi: 10.5315/wjh.v1.i1.1
49
Current viewpoints on platelet contribution to inflammation  
Julia Etulain, Mirta Schattner 
World J Hematol 1(4):14-21. Published online Dec 6, 2012. doi: 10.5315/wjh.v1.i4.14
50
Bone marrow cell death and proliferation: Controlling mechanisms in normal and leukemic state  
Morito Kurata, Shiho Suzuki, Shinya Abe, Iichiroh Onishi, Masanobu Kitagawa 
World J Hematol 2(1):1-5. Published online Feb 6, 2013. doi: 10.5315/wjh.v2.i1.1