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For: Scharschmidt TC, Man MQ, Hatano Y, Crumrine D, Gunathilake R, Sundberg JP, Silva KA, Mauro TM, Hupe M, Cho S. Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens. J Allergy Clin Immunol. 2009;124:496-506, 506.e1-6. [PMID: 19733297 DOI: 10.1016/j.jaci.2009.06.046] [Cited by in Crossref: 197] [Cited by in F6Publishing: 154] [Article Influence: 16.4] [Reference Citation Analysis]
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5 Domínguez-hüttinger E, Christodoulides P, Miyauchi K, Irvine AD, Okada-hatakeyama M, Kubo M, Tanaka RJ. Mathematical modeling of atopic dermatitis reveals “double-switch” mechanisms underlying 4 common disease phenotypes. Journal of Allergy and Clinical Immunology 2017;139:1861-1872.e7. [DOI: 10.1016/j.jaci.2016.10.026] [Cited by in Crossref: 25] [Cited by in F6Publishing: 17] [Article Influence: 6.3] [Reference Citation Analysis]
6 Man M, Sun R, Man G, Lee D, Hill Z, Elias PM. Commonly Employed African Neonatal Skin Care Products Compromise Epidermal Function in Mice. Pediatr Dermatol 2016;33:493-500. [DOI: 10.1111/pde.12901] [Cited by in Crossref: 4] [Cited by in F6Publishing: 2] [Article Influence: 0.8] [Reference Citation Analysis]
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11 Dang E, Man G, Lee D, Crumrine DA, Mauro TM, Elias PM, Man MQ. Mutations in 3β-hydroxysteroid-δ8, δ7-isomerase paradoxically benefit epidermal permeability barrier homeostasis in mice. Exp Dermatol 2021;30:384-9. [PMID: 33205489 DOI: 10.1111/exd.14236] [Reference Citation Analysis]
12 Song C, Liu L, Chen J, Hu Y, Li J, Wang B, Bellusci S, Chen C, Dong N. Evidence for the critical role of the PI3K signaling pathway in particulate matter-induced dysregulation of the inflammatory mediators COX-2/PGE2 and the associated epithelial barrier protein Filaggrin in the bronchial epithelium. Cell Biol Toxicol 2020;36:301-13. [PMID: 31884678 DOI: 10.1007/s10565-019-09508-1] [Cited by in Crossref: 1] [Cited by in F6Publishing: 3] [Article Influence: 0.5] [Reference Citation Analysis]
13 Landeck L, Visser M, Skudlik C, Brans R, Kezic S, John SM. No remarkable differences in rates of sensitization to common type I and IV allergens between FLG loss-of-function mutation carriers and wild-type subjects: TYPE I AND IV SENSITIZATION IN FLG MUTATION CARRIERS. Contact Dermatitis 2014;70:27-34. [DOI: 10.1111/cod.12109] [Cited by in Crossref: 8] [Cited by in F6Publishing: 4] [Article Influence: 1.0] [Reference Citation Analysis]
14 Goleva E, Berdyshev E, Leung DY. Epithelial barrier repair and prevention of allergy. J Clin Invest 2019;129:1463-74. [PMID: 30776025 DOI: 10.1172/JCI124608] [Cited by in Crossref: 57] [Cited by in F6Publishing: 21] [Article Influence: 28.5] [Reference Citation Analysis]
15 Wang Z, Man MQ, Li T, Elias PM, Mauro TM. Aging-associated alterations in epidermal function and their clinical significance. Aging (Albany NY) 2020;12:5551-65. [PMID: 32217811 DOI: 10.18632/aging.102946] [Cited by in Crossref: 11] [Cited by in F6Publishing: 8] [Article Influence: 11.0] [Reference Citation Analysis]
16 Gunathilake R, Schmuth M, Scharschmidt TC, Gruber R, Grabher D, Leslie KS, Maurer TA, Mauro TM, Elias PM. Epidermal barrier dysfunction in non-atopic HIV: evidence for an "inside-to-outside" pathogenesis. J Invest Dermatol 2010;130:1185-8. [PMID: 19924137 DOI: 10.1038/jid.2009.367] [Cited by in Crossref: 11] [Cited by in F6Publishing: 7] [Article Influence: 0.9] [Reference Citation Analysis]
17 Ye L, Lv C, Man G, Song S, Elias PM, Man MQ. Abnormal epidermal barrier recovery in uninvolved skin supports the notion of an epidermal pathogenesis of psoriasis. J Invest Dermatol 2014;134:2843-6. [PMID: 24780930 DOI: 10.1038/jid.2014.205] [Cited by in Crossref: 34] [Cited by in F6Publishing: 28] [Article Influence: 4.9] [Reference Citation Analysis]
18 Berg ND, Husemoen LL, Thuesen BH, Hersoug LG, Elberling J, Thyssen JP, Carlsen BC, Johansen JD, Menné T, Bønnelykke K, Stender S, Meldgaard M, Szecsi PB, Linneberg A. Interaction between filaggrin null mutations and tobacco smoking in relation to asthma. J Allergy Clin Immunol 2012;129:374-80, 380.e1-2. [PMID: 22088612 DOI: 10.1016/j.jaci.2011.08.045] [Cited by in Crossref: 30] [Cited by in F6Publishing: 25] [Article Influence: 3.0] [Reference Citation Analysis]
19 Gaffal E, Glodde N, Jakobs M, Bald T, Tüting T. Cannabinoid 1 receptors in keratinocytes attenuate fluorescein isothiocyanate-induced mouse atopic-like dermatitis. Exp Dermatol 2014;23:401-6. [DOI: 10.1111/exd.12414] [Cited by in Crossref: 15] [Cited by in F6Publishing: 11] [Article Influence: 2.1] [Reference Citation Analysis]
20 Hartmann B, Riedel R, Jörß K, Loddenkemper C, Steinmeyer A, Zügel U, Babina M, Radbruch A, Worm M. Vitamin D Receptor Activation Improves Allergen-Triggered Eczema in Mice. Journal of Investigative Dermatology 2012;132:330-6. [DOI: 10.1038/jid.2011.296] [Cited by in Crossref: 30] [Cited by in F6Publishing: 23] [Article Influence: 3.3] [Reference Citation Analysis]
21 Hou M, Man M, Man W, Zhu W, Hupe M, Park K, Crumrine D, Elias PM, Man MQ. Topical hesperidin improves epidermal permeability barrier function and epidermal differentiation in normal murine skin. Exp Dermatol 2012;21:337-40. [PMID: 22509829 DOI: 10.1111/j.1600-0625.2012.01455.x] [Cited by in Crossref: 31] [Cited by in F6Publishing: 23] [Article Influence: 3.4] [Reference Citation Analysis]
22 Tsakok T, Woolf R, Smith CH, Weidinger S, Flohr C. Atopic dermatitis: the skin barrier and beyond. Br J Dermatol 2019;180:464-74. [PMID: 29969827 DOI: 10.1111/bjd.16934] [Cited by in Crossref: 54] [Cited by in F6Publishing: 42] [Article Influence: 18.0] [Reference Citation Analysis]
23 Schäfer M, Farwanah H, Willrodt AH, Huebner AJ, Sandhoff K, Roop D, Hohl D, Bloch W, Werner S. Nrf2 links epidermal barrier function with antioxidant defense. EMBO Mol Med 2012;4:364-79. [PMID: 22383093 DOI: 10.1002/emmm.201200219] [Cited by in Crossref: 106] [Cited by in F6Publishing: 96] [Article Influence: 11.8] [Reference Citation Analysis]
24 Patrick GJ, Archer NK, Miller LS. Which Way Do We Go? Complex Interactions in Atopic Dermatitis Pathogenesis. J Invest Dermatol 2021;141:274-84. [PMID: 32943210 DOI: 10.1016/j.jid.2020.07.006] [Cited by in Crossref: 4] [Cited by in F6Publishing: 5] [Article Influence: 4.0] [Reference Citation Analysis]
25 Bognar P, Nemeth I, Mayer B, Haluszka D, Wikonkal N, Ostorhazi E, John S, Paulsson M, Smyth N, Pasztoi M, Buzas EI, Szipocs R, Kolonics A, Temesvari E, Karpati S. Reduced inflammatory threshold indicates skin barrier defect in transglutaminase 3 knockout mice. J Invest Dermatol 2014;134:105-11. [PMID: 23884312 DOI: 10.1038/jid.2013.307] [Cited by in Crossref: 26] [Cited by in F6Publishing: 23] [Article Influence: 3.3] [Reference Citation Analysis]
26 Nam YK, Kim MH, Ha IJ, Yang WM. Derma-Hc, a New Developed Herbal Formula, Ameliorates Cutaneous Lichenification in Atopic Dermatitis. Int J Mol Sci 2021;22:2359. [PMID: 33652999 DOI: 10.3390/ijms22052359] [Reference Citation Analysis]
27 Jennemann R, Rabionet M, Gorgas K, Epstein S, Dalpke A, Rothermel U, Bayerle A, van der Hoeven F, Imgrund S, Kirsch J, Nickel W, Willecke K, Riezman H, Gröne HJ, Sandhoff R. Loss of ceramide synthase 3 causes lethal skin barrier disruption. Hum Mol Genet 2012;21:586-608. [PMID: 22038835 DOI: 10.1093/hmg/ddr494] [Cited by in Crossref: 175] [Cited by in F6Publishing: 157] [Article Influence: 17.5] [Reference Citation Analysis]
28 Holgate ST. Pathophysiology of asthma: what has our current understanding taught us about new therapeutic approaches? J Allergy Clin Immunol 2011;128:495-505. [PMID: 21807404 DOI: 10.1016/j.jaci.2011.06.052] [Cited by in Crossref: 98] [Cited by in F6Publishing: 94] [Article Influence: 9.8] [Reference Citation Analysis]
29 Wen S, Sun M, Ye L, Yang B, Hu L, Man MQ. Topical Applications of a Novel Emollient Inhibit Inflammation in Murine Models of Acute Contact Dermatitis. Biomed Res Int 2021;2021:5594646. [PMID: 33954180 DOI: 10.1155/2021/5594646] [Reference Citation Analysis]
30 Janssens M, van Smeden J, Gooris GS, Bras W, Portale G, Caspers PJ, Vreeken RJ, Hankemeier T, Kezic S, Wolterbeek R. Increase in short-chain ceramides correlates with an altered lipid organization and decreased barrier function in atopic eczema patients. J Lipid Res. 2012;53:2755-2766. [PMID: 23024286 DOI: 10.1194/jlr.p030338] [Cited by in Crossref: 234] [Cited by in F6Publishing: 89] [Article Influence: 26.0] [Reference Citation Analysis]
31 Amen N, Mathow D, Rabionet M, Sandhoff R, Langbein L, Gretz N, Jäckel C, Gröne H, Jennemann R. Differentiation of epidermal keratinocytes is dependent on glucosylceramide:ceramide processing. Human Molecular Genetics 2013;22:4164-79. [DOI: 10.1093/hmg/ddt264] [Cited by in Crossref: 34] [Cited by in F6Publishing: 31] [Article Influence: 4.3] [Reference Citation Analysis]
32 Man MQ, Hu LZ, Elias PM. Herbal Medicines Prevent the Development of Atopic Dermatitis by Multiple Mechanisms. Chin J Integr Med 2019;25:151-60. [PMID: 26740223 DOI: 10.1007/s11655-015-2438-1] [Cited by in Crossref: 5] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
33 Overgaard LEK, Main KM, Frederiksen H, Stender S, Szecsi PB, Williams HC, Thyssen JP. Children with atopic dermatitis and frequent emollient use have increased urinary levels of low-molecular-weight phthalate metabolites and parabens. Allergy 2017;72:1768-77. [PMID: 28281298 DOI: 10.1111/all.13157] [Cited by in Crossref: 26] [Cited by in F6Publishing: 21] [Article Influence: 6.5] [Reference Citation Analysis]
34 Bandier J, Carlsen B, Rasmussen M, Petersen L, Johansen J. Skin reaction and regeneration after single sodium lauryl sulfate exposure stratified by filaggrin genotype and atopic dermatitis phenotype. Br J Dermatol 2015;172:1519-29. [DOI: 10.1111/bjd.13651] [Cited by in Crossref: 20] [Cited by in F6Publishing: 12] [Article Influence: 3.3] [Reference Citation Analysis]
35 Jarrett R, Salio M, Lloyd-Lavery A, Subramaniam S, Bourgeois E, Archer C, Cheung KL, Hardman C, Chandler D, Salimi M, Gutowska-Owsiak D, de la Serna JB, Fallon PG, Jolin H, Mckenzie A, Dziembowski A, Podobas EI, Bal W, Johnson D, Moody DB, Cerundolo V, Ogg G. Filaggrin inhibits generation of CD1a neolipid antigens by house dust mite-derived phospholipase. Sci Transl Med 2016;8:325ra18. [PMID: 26865566 DOI: 10.1126/scitranslmed.aad6833] [Cited by in Crossref: 55] [Cited by in F6Publishing: 48] [Article Influence: 11.0] [Reference Citation Analysis]
36 Halling-overgaard A, Kezic S, Jakasa I, Engebretsen K, Maibach H, Thyssen J. Skin absorption through atopic dermatitis skin: a systematic review. Br J Dermatol 2017;177:84-106. [DOI: 10.1111/bjd.15065] [Cited by in Crossref: 60] [Cited by in F6Publishing: 47] [Article Influence: 15.0] [Reference Citation Analysis]
37 Shaughnessy CN, Malajian D, Belsito DV. Cutaneous delayed-type hypersensitivity in patients with atopic dermatitis: Reactivity to surfactants. Journal of the American Academy of Dermatology 2014;70:704-8. [DOI: 10.1016/j.jaad.2013.12.009] [Cited by in Crossref: 36] [Cited by in F6Publishing: 32] [Article Influence: 5.1] [Reference Citation Analysis]
38 Visser MJ, Landeck L, Campbell LE, McLean WH, Weidinger S, Calkoen F, John SM, Kezic S. Impact of atopic dermatitis and loss-of-function mutations in the filaggrin gene on the development of occupational irritant contact dermatitis. Br J Dermatol. 2013;168:326-332. [PMID: 23039796 DOI: 10.1111/bjd.12083] [Cited by in Crossref: 89] [Cited by in F6Publishing: 47] [Article Influence: 11.1] [Reference Citation Analysis]
39 Shin KO, Crumrine DA, Kim S, Lee Y, Kim B, Abuabara K, Park C, Uchida Y, Wakefield JS, Meyer JM, Jeong S, Park BD, Park K, Elias PM. Phenotypic overlap between atopic dermatitis and autism. BMC Neurosci 2021;22:43. [PMID: 34157971 DOI: 10.1186/s12868-021-00645-0] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
40 Petersen TH, Jee MH, Gadsbøll AØ, Schmidt JD, Sloth JJ, Sonnenberg GF, Geisler C, Thyssen JP, Bonefeld CM. Mice with epidermal filaggrin deficiency show increased immune reactivity to nickel. Contact Dermatitis 2018;80:139-48. [DOI: 10.1111/cod.13153] [Cited by in Crossref: 12] [Cited by in F6Publishing: 6] [Article Influence: 4.0] [Reference Citation Analysis]
41 Jakasa I, Koster ES, Calkoen F, Irwin Mclean W, Campbell LE, Bos JD, Verberk MM, Kezic S. Skin Barrier Function in Healthy Subjects and Patients with Atopic Dermatitis in Relation to Filaggrin Loss-of-Function Mutations. Journal of Investigative Dermatology 2011;131:540-2. [DOI: 10.1038/jid.2010.307] [Cited by in Crossref: 66] [Cited by in F6Publishing: 55] [Article Influence: 6.6] [Reference Citation Analysis]
42 Hoste E, Kemperman P, Devos M, Denecker G, Kezic S, Yau N, Gilbert B, Lippens S, De Groote P, Roelandt R, Van Damme P, Gevaert K, Presland RB, Takahara H, Puppels G, Caspers P, Vandenabeele P, Declercq W. Caspase-14 is required for filaggrin degradation to natural moisturizing factors in the skin. J Invest Dermatol 2011;131:2233-41. [PMID: 21654840 DOI: 10.1038/jid.2011.153] [Cited by in Crossref: 122] [Cited by in F6Publishing: 92] [Article Influence: 12.2] [Reference Citation Analysis]
43 Bonefeld CM, Geisler C, Gimenéz-arnau E, Lepoittevin J, Uter W, Johansen JD. Immunological, chemical and clinical aspects of exposure to mixtures of contact allergens. Contact Dermatitis 2017;77:133-42. [DOI: 10.1111/cod.12847] [Cited by in Crossref: 23] [Cited by in F6Publishing: 14] [Article Influence: 5.8] [Reference Citation Analysis]
44 Kaae J, Menné T, Thyssen JP. Severe occupational protein contact dermatitis caused by fish in 2 patients with filaggrin mutations. Contact Dermatitis 2013;68:319-20. [PMID: 23601069 DOI: 10.1111/cod.12031] [Cited by in Crossref: 6] [Cited by in F6Publishing: 2] [Article Influence: 0.8] [Reference Citation Analysis]
45 Nakai K, Yoneda K, Hosokawa Y, Moriue T, Presland RB, Fallon PG, Kabashima K, Kosaka H, Kubota Y. Reduced expression of epidermal growth factor receptor, E-cadherin, and occludin in the skin of flaky tail mice is due to filaggrin and loricrin deficiencies. Am J Pathol. 2012;181:969-977. [PMID: 22796440 DOI: 10.1016/j.ajpath.2012.06.005] [Cited by in Crossref: 33] [Cited by in F6Publishing: 25] [Article Influence: 3.7] [Reference Citation Analysis]
46 Thyssen JP, Linneberg A, Ross-hansen K, Carlsen BC, Meldgaard M, Szecsi PB, Stender S, Menné T, Johansen JD. Filaggrin mutations are strongly associated with contact sensitization in individuals with dermatitis. Contact Dermatitis 2013;68:273-6. [DOI: 10.1111/cod.12021] [Cited by in Crossref: 62] [Cited by in F6Publishing: 39] [Article Influence: 7.8] [Reference Citation Analysis]
47 Park J, Jekarl DW, Kim Y, Kim J, Kim M, Park YM. Novel FLG null mutations in Korean patients with atopic dermatitis and comparison of the mutational spectra in Asian populations. J Dermatol 2015;42:867-73. [DOI: 10.1111/1346-8138.12935] [Cited by in Crossref: 26] [Cited by in F6Publishing: 21] [Article Influence: 4.3] [Reference Citation Analysis]
48 Landeck L, Visser M, Skudlik C, Brans R, Kezic S, John SM. Clinical course of occupational irritant contact dermatitis of the hands in relation to filaggrin genotype status and atopy. Br J Dermatol 2012;167:1302-9. [PMID: 22962861 DOI: 10.1111/bjd.12035] [Cited by in Crossref: 50] [Cited by in F6Publishing: 26] [Article Influence: 6.3] [Reference Citation Analysis]
49 Rerknimitr P, Otsuka A, Nakashima C, Kabashima K. The etiopathogenesis of atopic dermatitis: barrier disruption, immunological derangement, and pruritus. Inflamm Regen 2017;37:14. [PMID: 29259713 DOI: 10.1186/s41232-017-0044-7] [Cited by in Crossref: 55] [Cited by in F6Publishing: 42] [Article Influence: 13.8] [Reference Citation Analysis]
50 Meng L, Wang L, Tang H, Tang X, Jiang X, Zhao J, Gao J, Li B, Fu X, Chen Y, Yao W, Zhan W, Wu B, Duan D, Shen C, Cheng H, Zuo X, Yang S, Sun L, Zhang X. Filaggrin gene mutation c.3321delA is associated with various clinical features of atopic dermatitis in the Chinese Han population. PLoS One 2014;9:e98235. [PMID: 24858702 DOI: 10.1371/journal.pone.0098235] [Cited by in Crossref: 18] [Cited by in F6Publishing: 17] [Article Influence: 2.6] [Reference Citation Analysis]
51 Bains SN, Nash P, Fonacier L. Irritant Contact Dermatitis. Clinic Rev Allerg Immunol 2019;56:99-109. [DOI: 10.1007/s12016-018-8713-0] [Cited by in Crossref: 31] [Cited by in F6Publishing: 17] [Article Influence: 10.3] [Reference Citation Analysis]
52 Okano J, Lichti U, Mamiya S, Aronova M, Zhang G, Yuspa SH, Hamada H, Sakai Y, Morasso MI. Increased retinoic acid levels through ablation of Cyp26b1 determine the processes of embryonic skin barrier formation and peridermal development. J Cell Sci 2012;125:1827-36. [PMID: 22366455 DOI: 10.1242/jcs.101550] [Cited by in Crossref: 31] [Cited by in F6Publishing: 25] [Article Influence: 3.4] [Reference Citation Analysis]
53 Dębińska A. New Treatments for Atopic Dermatitis Targeting Skin Barrier Repair via the Regulation of FLG Expression. J Clin Med 2021;10:2506. [PMID: 34198894 DOI: 10.3390/jcm10112506] [Reference Citation Analysis]
54 Olivry T, Wofford J, Paps JS, Dunston SM. Stratum corneum removal facilitates experimental sensitization to mite allergens in atopic dogs: Stratum corneum removal in atopic dogs. Veterinary Dermatology 2011;22:188-96. [DOI: 10.1111/j.1365-3164.2010.00938.x] [Cited by in Crossref: 35] [Cited by in F6Publishing: 26] [Article Influence: 3.2] [Reference Citation Analysis]
55 Brough HA, Nadeau KC, Sindher SB, Alkotob SS, Chan S, Bahnson HT, Leung DYM, Lack G. Epicutaneous sensitization in the development of food allergy: What is the evidence and how can this be prevented? Allergy 2020;75:2185-205. [PMID: 32249942 DOI: 10.1111/all.14304] [Cited by in Crossref: 27] [Cited by in F6Publishing: 22] [Article Influence: 27.0] [Reference Citation Analysis]
56 Fortugno P, Furio L, Teson M, Berretti M, El Hachem M, Zambruno G, Hovnanian A, D'alessio M. The 420K LEKTI variant alters LEKTI proteolytic activation and results in protease deregulation: implications for atopic dermatitis. Human Molecular Genetics 2012;21:4187-200. [DOI: 10.1093/hmg/dds243] [Cited by in Crossref: 57] [Cited by in F6Publishing: 48] [Article Influence: 6.3] [Reference Citation Analysis]
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