Copyright ©The Author(s) 2018.
World J Orthop. Nov 18, 2018; 9(11): 255-261
Published online Nov 18, 2018. doi: 10.5312/wjo.v9.i11.255
Figure 3
Figure 3 Anti-inflammatory effect of sanguinarine. Sanguinarine acts as suppressor of IL-1β, targeting the pathways involved in JNK activation and the degradation of IκBα, an inhibitory subunit of NF-κB. IL: Interleukin; IκBα: Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; NF-κB: Nuclear factor kappa B; JNK: c-Jun N-terminal kinases; MKK7: Dual specificity mitogen-activated protein kinase kinase 7.