Copyright ©The Author(s) 2019.
World J Clin Oncol. Sep 24, 2019; 10(9): 300-302
Published online Sep 24, 2019. doi: 10.5306/wjco.v10.i9.300
Table 1 Differences in gangliocytic paraganglioma and gastrointestinal neuroendocrine tumor G1
Gangliocytic paragangliomaGastrointestinal neuroendocrine tumor G1
Predominant site of the primary tumorDuodenum (approximately 90%)Small intestine, but duodenal is relatively rare
5-yr survival ratesExcellent (approximately 100%)Good (approximately 80%)
IncidenceExtremely rareRelatively rare, but gradually increasing, incidence worldwide
Morphological findings obtained by surgeryEpithelioid, spindle, and ganglion-like cellsNesting, trabecular pattern, and/or rosette formation with nuclear palisading
Immunohistochemistry (pancreatic polypeptide and progesterone receptor)Epithelioid cells show positive reactivity for both.Tumor cells show negative reactivity for both
PerspectiveAccurate diagnosis of gangliocytic paraganglioma will facilitate the use of less invasive treatment procedures