Published online Jun 28, 2014. doi: 10.4329/wjr.v6.i6.261
Revised: February 7, 2014
Accepted: May 16, 2014
Published online: June 28, 2014
Core tip: In the present paper, we systematically reviewed functional magnetic resonance imaging studies investigating sustained attention in affective and non-affective psychosis. We found that differences between cases (patients, unaffected relatives of psychotic probands) and controls in terms of functional activation of sustained attention system structures were detectable even when the groups performed comparably. In particular, the insular cortex seems to be a trait marker for psychosis in general, whereas other regions (thalamus, cingulate cortex, amygdala) seem to be differently impaired in affective and non-affective psychosis.