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Dr. Mani is Associate Professor of Radiology at the Translational and Molecular Imaging Institute (TMII) of the Icahn School of Medicine at Mount Sinai, New York. Dr. Mani completed his Bachelors degree in Biomedical Engineering from the prestigious Manipal Institute of Technology in India and moved to the USA to pursue his graduate education. He completed his MS and PhD also in Biomedical Engineering from the Medical College of Virginia, Virginia Commonwealth University in 2002. He then moved to Mount Sinai Hospital in New York for his post doctoral work focusing on cardiovascular magnetic resonance imaging. He was promoted to Instructor in 2008, Assistant Professor in 2012 and Associate Professor in 2017. His main interests are in imaging of cardiovascular diseases , specifically focusing on atherosclerosis, thrombosis and their complications using FDG-PET, CT and MRI. He has  ~100 peer reviewed publications, numerous book chapters and several US patents in the field of cardiovascular imaging. He serves on the Institutional Review Board of Mount Sinai (IRB), is part of the American Heart Association (AHA) Radiology and Surgery grants peer review committee and also serves on several ad hoc review panels for the National Institute of Health (NIH).

Dr. Mani is also the Director of the Cardiovascular Imaging Clinical Trials Unit (CICTU) at TMII. As part of this responsibility,  he works to translate novel multi-modality imaging techniques for use in multicenter clinical trials. The CICTU is composed of clinicians, image processing and programming experts, image analysts, data managers, IT personnel and research coordinators. It is a modern hybrid between a contract research organization (CRO) and an imaging core lab. It undertakes and manages all aspects; ranging from scientific conduct to administrative management of clinical trials with imaging endpoints led by TMII. Tasks span from industry or federally sponsored multicenter clinical trials to the support of individual investigators interested in using imaging endpoints for their work. Typical services offered include but are not limited to trial design and consultation, imaging protocol development, site training and qualification, data repository and database management, data quality control and analysis, and publication support.