Fibrinogen-thrombin collagen patch reinforcement of high-risk colonic anastomoses in rats

Table 2 Histopathologic Biert’ scheme

Parameters	Score
	0	1	2	3
Necrosis	No	Small patches	Large patches	Massive
PMNs	Normal	Slightly increased	Strong infiltration	Massive infiltration
Lymphocytes	Normal	Slightly increased	Strong infiltration	Massive infiltration
Macrophages	Normal	Slightly increased	Strong infiltration	Massive infiltration
Edema	No	Slight	Strong	Massive
Epithelium	Glandular normal	Cubic normal	Cubic incomplete	Absent
Submucosa-muscular	Good bridges	Mild bridges	Few bridges	Bridges absent
Angiogenesis	Extensive	Strong	Slight	Absent
Fibrosis	Extensive	Strong	Slight	Absent

PMNs: Polymorphonuclear cells.