Systematic Reviews
Copyright ©The Author(s) 2020.
World J Diabetes. Mar 15, 2020; 11(3): 78-89
Published online Mar 15, 2020. doi: 10.4239/wjd.v11.i3.78
Table 1 Characteristics of the included studies
Ref.Study typeMale: Female ratioType 2 diabetes mellitus/Type 1 diabetesDuration of DiabetesHbA1c%Ulcer descriptionFollow-up months
Quilici et al[21]Cross-sectional study68 males and 32 femalesT2DM22% had for less than five yr; 24% had from 5-10 yr; 17% had from 10-15 yr; 16% had from 15-20 yr; 21% had for >20 yr-75% patients had Grade 4 ulcers; 20% had Grade 3 ulcers; 5% had Grade 2 ulcers-
Commons et al[26]Prospective study60% male and 40% femalesAll patients had T1DM, except of 7 patients-Median value was 8.8%Diabetic patients with ulcers or foot infections were referred14 mo
Barwell et al[28]Combination of literature review-T1DM and T2DM--Standardized using validated classifications schemes such as the University of Texas rating, SINBAD or IWGDF PEDIS-
Roth-Albin et al[24]Retrospective cohort study67.9% were males---Ulcer sizes > 1 cm252 wk
Fitzgerald et al[30]Retrospective study4:4-Average disease duration 22 yr-Active foot-ulcer with a wound swab taken15 mo
Kathirvel et al[22]Retrospective study74.6% males and 25.33% femalesT2DM< 5 yr - 40%; 5-10 yr - 34%; 10-15 yr - 17%; 15-20 yr - 7.3%; > 20 yr - 1.3%6%-7%Categorized into necrotic/non-necrotic; ulcers based on signs of infection-
Xie et al[16]Hospital-based retrospect study230 males and 158 femalesT2DM--Severity of ulcer was assessed by Wagner-Meggit classification system-
Dwedar et al[41]Observational prospective study48 males (57%) and 32 females (43%)-5-32 yr-Graded according to Wagner’s grade-
Abbas et al[45]Literature review-T2DM--Classified on the basis of wound debridement, pressure off-loading, glycemic control, surgical interventions, and occasionally other adjunctive measures-
Oliveira et al[46]Epidemiological, retrospective and descriptive study27 males and 30 females---Infected ulceration was associated with germs present in the community-