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For: Menini S, Iacobini C, Ricci C, Oddi G, Pesce C, Pugliese F, Block K, Abboud HE, Giorgio M, Migliaccio E, Pelicci PG, Pugliese G. Ablation of the gene encoding p66Shc protects mice against AGE-induced glomerulopathy by preventing oxidant-dependent tissue injury and further AGE accumulation. Diabetologia 2007;50:1997-2007. [DOI: 10.1007/s00125-007-0728-7] [Cited by in Crossref: 49] [Cited by in F6Publishing: 50] [Article Influence: 3.3] [Reference Citation Analysis]
Number Citing Articles
1 Sainz J, Sata M. When p66ShcA is away, mice EPCs sweetly play. Cardiovasc Res 2009;82:388-9. [PMID: 19351737 DOI: 10.1093/cvr/cvp111] [Reference Citation Analysis]
2 Chai M, Ji Q, Zhang H, Zhou Y, Yang Q, Zhou Y, Guo G, Liu W, Han W, Yang L, Zhang L, Liang J, Liu Y, Shi D, Zhao Y. The Protective Effect of Interleukin-37 on Vascular Calcification and Atherosclerosis in Apolipoprotein E-Deficient Mice with Diabetes. Journal of Interferon & Cytokine Research 2015;35:530-9. [DOI: 10.1089/jir.2014.0212] [Cited by in Crossref: 32] [Cited by in F6Publishing: 33] [Article Influence: 4.6] [Reference Citation Analysis]
3 Spescha RD, Shi Y, Wegener S, Keller S, Weber B, Wyss MM, Lauinger N, Tabatabai G, Paneni F, Cosentino F, Hock C, Weller M, Nitsch RM, Lüscher TF, Camici GG. Deletion of the ageing gene p66(Shc) reduces early stroke size following ischaemia/reperfusion brain injury. Eur Heart J 2013;34:96-103. [PMID: 23008506 DOI: 10.1093/eurheartj/ehs331] [Cited by in Crossref: 54] [Cited by in F6Publishing: 52] [Article Influence: 5.4] [Reference Citation Analysis]
4 Tomilov AA, Bicocca V, Schoenfeld RA, Giorgio M, Migliaccio E, Ramsey JJ, Hagopian K, Pelicci PG, Cortopassi GA. Decreased superoxide production in macrophages of long-lived p66Shc knock-out mice. J Biol Chem 2010;285:1153-65. [PMID: 19892704 DOI: 10.1074/jbc.M109.017491] [Cited by in Crossref: 44] [Cited by in F6Publishing: 26] [Article Influence: 3.4] [Reference Citation Analysis]
5 Kumar S. P66Shc and vascular endothelial function. Biosci Rep 2019;39:BSR20182134. [PMID: 30918103 DOI: 10.1042/BSR20182134] [Cited by in Crossref: 12] [Cited by in F6Publishing: 7] [Article Influence: 4.0] [Reference Citation Analysis]
6 Arany I, Clark J, Reed DK, Juncos LA. Chronic nicotine exposure augments renal oxidative stress and injury through transcriptional activation of p66shc. Nephrol Dial Transplant 2013;28:1417-25. [PMID: 23328708 DOI: 10.1093/ndt/gfs596] [Cited by in Crossref: 29] [Cited by in F6Publishing: 30] [Article Influence: 3.2] [Reference Citation Analysis]
7 Serban AI, Stanca L, Geicu OI, Dinischiotu A. AGEs-Induced IL-6 Synthesis Precedes RAGE Up-Regulation in HEK 293 Cells: An Alternative Inflammatory Mechanism? Int J Mol Sci 2015;16:20100-17. [PMID: 26307981 DOI: 10.3390/ijms160920100] [Cited by in Crossref: 11] [Cited by in F6Publishing: 13] [Article Influence: 1.6] [Reference Citation Analysis]
8 Riad A, Westermann D, Van Linthout S, Mohr Z, Uyulmaz S, Becher PM, Rütten H, Wohlfart P, Peters H, Schultheiss HP, Tschöpe C. Enhancement of endothelial nitric oxide synthase production reverses vascular dysfunction and inflammation in the hindlimbs of a rat model of diabetes. Diabetologia 2008;51:2325-32. [PMID: 18825362 DOI: 10.1007/s00125-008-1159-9] [Cited by in Crossref: 25] [Cited by in F6Publishing: 22] [Article Influence: 1.8] [Reference Citation Analysis]
9 Liang YJ, Jian JH, Liu YC, Juang SJ, Shyu KG, Lai LP, Wang BW, Leu JG. Advanced glycation end products-induced apoptosis attenuated by PPARdelta activation and epigallocatechin gallate through NF-kappaB pathway in human embryonic kidney cells and human mesangial cells. Diabetes Metab Res Rev 2010;26:406-16. [PMID: 20583309 DOI: 10.1002/dmrr.1100] [Cited by in Crossref: 34] [Cited by in F6Publishing: 34] [Article Influence: 2.8] [Reference Citation Analysis]
10 Shi Y, Camici GG, Lüscher TF. Cardiovascular determinants of life span. Pflugers Arch - Eur J Physiol 2010;459:315-24. [DOI: 10.1007/s00424-009-0727-2] [Cited by in Crossref: 31] [Cited by in F6Publishing: 26] [Article Influence: 2.4] [Reference Citation Analysis]
11 Yang S, Xiao L, Li J, Liu F, Sun L. Oxidative stress, a common molecular pathway for kidney disease: Role of the redox enzyme p66Shc. Renal Failure 2013;36:313-20. [DOI: 10.3109/0886022x.2013.846867] [Cited by in Crossref: 20] [Cited by in F6Publishing: 9] [Article Influence: 2.2] [Reference Citation Analysis]
12 Derungs R, Camici GG, Spescha RD, Welt T, Tackenberg C, Späni C, Wirth F, Grimm A, Eckert A, Nitsch RM, Kulic L. Genetic ablation of the p66Shc adaptor protein reverses cognitive deficits and improves mitochondrial function in an APP transgenic mouse model of Alzheimer’s disease. Mol Psychiatry 2017;22:605-14. [DOI: 10.1038/mp.2016.112] [Cited by in Crossref: 14] [Cited by in F6Publishing: 15] [Article Influence: 2.3] [Reference Citation Analysis]
13 Chen S, Ji B, Yan Y, He X, Han K, Dai Q, Zhang M, Mo Y, Wang J. Carnosic acid attenuates neuropathic pain in rat through the activation of spinal sirtuin1 and down-regulation of p66shc expression. Neurochemistry International 2016;93:95-102. [DOI: 10.1016/j.neuint.2016.01.004] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 1.2] [Reference Citation Analysis]
14 Bock F, Shahzad K, Wang H, Stoyanov S, Wolter J, Dong W, Pelicci PG, Kashif M, Ranjan S, Schmidt S, Ritzel R, Schwenger V, Reymann KG, Esmon CT, Madhusudhan T, Nawroth PP, Isermann B. Activated protein C ameliorates diabetic nephropathy by epigenetically inhibiting the redox enzyme p66Shc. Proc Natl Acad Sci U S A 2013;110:648-53. [PMID: 23267072 DOI: 10.1073/pnas.1218667110] [Cited by in Crossref: 90] [Cited by in F6Publishing: 85] [Article Influence: 9.0] [Reference Citation Analysis]
15 Diogo CV, Suski JM, Lebiedzinska M, Karkucinska-Wieckowska A, Wojtala A, Pronicki M, Duszynski J, Pinton P, Portincasa P, Oliveira PJ, Wieckowski MR. Cardiac mitochondrial dysfunction during hyperglycemia--the role of oxidative stress and p66Shc signaling. Int J Biochem Cell Biol 2013;45:114-22. [PMID: 22776741 DOI: 10.1016/j.biocel.2012.07.004] [Cited by in Crossref: 27] [Cited by in F6Publishing: 26] [Article Influence: 2.7] [Reference Citation Analysis]
16 Iacobini C, Vitale M, Pesce C, Pugliese G, Menini S. Diabetic Complications and Oxidative Stress: A 20-Year Voyage Back in Time and Back to the Future. Antioxidants (Basel) 2021;10:727. [PMID: 34063078 DOI: 10.3390/antiox10050727] [Cited by in Crossref: 5] [Cited by in F6Publishing: 4] [Article Influence: 5.0] [Reference Citation Analysis]
17 Yan H, Jihong Y, Feng Z, Xiaomei X, Xiaohan Z, Guangzhi W, Zhenhai M, Dongyan G, Xiaochi M, Qing F, Kexin L, Xiaofeng T. Sirtuin 1-Mediated Inhibition of p66shc Expression Alleviates Liver Ischemia/Reperfusion Injury: . Critical Care Medicine 2014;42:e373-81. [DOI: 10.1097/ccm.0000000000000246] [Cited by in Crossref: 37] [Cited by in F6Publishing: 20] [Article Influence: 4.6] [Reference Citation Analysis]
18 Giorgio M, Stendardo M, Migliaccio E, Pelicci PG. P66SHC deletion improves fertility and progeric phenotype of late-generation TERC-deficient mice but not their short lifespan. Aging Cell 2016;15:446-54. [PMID: 26968134 DOI: 10.1111/acel.12448] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 1.2] [Reference Citation Analysis]
19 Menini S, Iacobini C, de Latouliere L, Manni I, Ionta V, Blasetti Fantauzzi C, Pesce C, Cappello P, Novelli F, Piaggio G, Pugliese G. The advanced glycation end-product Nϵ -carboxymethyllysine promotes progression of pancreatic cancer: implications for diabetes-associated risk and its prevention. J Pathol 2018;245:197-208. [PMID: 29533466 DOI: 10.1002/path.5072] [Cited by in F6Publishing: 25] [Reference Citation Analysis]
20 Teng L, Fan L, Peng Y, He X, Chen H, Duan H, Yang F, Lin D, Lin Z, Li H, Shao B. Carnosic Acid Mitigates Early Brain Injury After Subarachnoid Hemorrhage: Possible Involvement of the SIRT1/p66shc Signaling Pathway. Front Neurosci 2019;13:26. [PMID: 30890904 DOI: 10.3389/fnins.2019.00026] [Cited by in Crossref: 5] [Cited by in F6Publishing: 4] [Article Influence: 1.7] [Reference Citation Analysis]
21 Hatamipour M, Ramezani M, Tabassi SAS, Johnston TP, Sahebkar A. Demethoxycurcumin: A naturally occurring curcumin analogue for treating non-cancerous diseases. J Cell Physiol 2019;234:19320-30. [PMID: 31344992 DOI: 10.1002/jcp.28626] [Cited by in Crossref: 12] [Cited by in F6Publishing: 12] [Article Influence: 4.0] [Reference Citation Analysis]
22 Casagrande V, Iuliani G, Menini S, Pugliese G, Federici M, Menghini R. Restoration of renal TIMP3 levels via genetics and pharmacological approach prevents experimental diabetic nephropathy. Clin Transl Med 2021;11:e305. [PMID: 33634991 DOI: 10.1002/ctm2.305] [Cited by in Crossref: 2] [Cited by in F6Publishing: 3] [Article Influence: 2.0] [Reference Citation Analysis]
23 Ren C, Zhou X, Bao X, Zhang J, Tang J, Zhu Z, Zhang N, Bai Y, Xi Y, Zhang Q, Ma B. Dioscorea zingiberensis ameliorates diabetic nephropathy by inhibiting NLRP3 inflammasome and curbing the expression of p66Shc in high-fat diet/streptozotocin-induced diabetic mice. J Pharm Pharmacol 2021;73:1218-29. [PMID: 34061184 DOI: 10.1093/jpp/rgab053] [Reference Citation Analysis]
24 Xing Y, Zhang X, Song X, Lv Z, Hou L, Li F. Injury of cortical neurons is caused by the advanced glycation end products-mediated pathway. Neural Regen Res 2013;8:909-15. [PMID: 25206382 DOI: 10.3969/j.issn.1673-5374.2013.10.005] [Cited by in F6Publishing: 4] [Reference Citation Analysis]
25 Huang TT, Sun WJ, Liu HY, Ma HL, Cui BX. p66Shc-mediated oxidative stress is involved in gestational diabetes mellitus. World J Diabetes 2021; 12(11): 1894-1907 [PMID: 34888014 DOI: 10.4239/wjd.v12.i11.1894] [Reference Citation Analysis]
26 Sticozzi C, Pecorelli A, Lim Y, Maioli E, Pagnin E, Davis PA, Valacchi G. Modulation of skin oxidative stress and inflammatory markers by environmental stressors. Differences between young and old. Journal of Dermatological Science 2012;65:226-8. [DOI: 10.1016/j.jdermsci.2011.11.004] [Cited by in Crossref: 10] [Cited by in F6Publishing: 10] [Article Influence: 1.0] [Reference Citation Analysis]
27 Avogaro A, de Kreutzenberg SV, Federici M, Fadini GP. The endothelium abridges insulin resistance to premature aging. J Am Heart Assoc 2013;2:e000262. [PMID: 23917532 DOI: 10.1161/JAHA.113.000262] [Cited by in Crossref: 17] [Cited by in F6Publishing: 9] [Article Influence: 1.9] [Reference Citation Analysis]
28 Menini S, Iacobini C, Fantauzzi CB, Pugliese G. L-carnosine and its Derivatives as New Therapeutic Agents for the Prevention and Treatment of Vascular Complications of Diabetes. Curr Med Chem 2020;27:1744-63. [PMID: 31296153 DOI: 10.2174/0929867326666190711102718] [Cited by in Crossref: 10] [Cited by in F6Publishing: 10] [Article Influence: 5.0] [Reference Citation Analysis]
29 Xi G, Shen X, Radhakrishnan Y, Maile L, Clemmons D. Hyperglycemia-induced p66shc inhibits insulin-like growth factor I-dependent cell survival via impairment of Src kinase-mediated phosphoinositide-3 kinase/AKT activation in vascular smooth muscle cells. Endocrinology 2010;151:3611-23. [PMID: 20534722 DOI: 10.1210/en.2010-0242] [Cited by in Crossref: 12] [Cited by in F6Publishing: 13] [Article Influence: 1.0] [Reference Citation Analysis]
30 Wang G, Yao J, Jing H, Zhang F, Lin M, Shi L, Wu H, Gao D, Liu K, Tian X. Suppression of the p66shc adapter protein by protocatechuic acid prevents the development of lung injury induced by intestinal ischemia reperfusion in mice. Journal of Trauma and Acute Care Surgery 2012;73:1130-7. [DOI: 10.1097/ta.0b013e318265d069] [Cited by in Crossref: 12] [Cited by in F6Publishing: 4] [Article Influence: 1.2] [Reference Citation Analysis]
31 Yang X, Xu R, Lin Y, Zhen Y, Wei J, Hu G, Sun H. Recombinant adenovirus of human p66Shc inhibits MCF-7 cell proliferation. Sci Rep 2016;6:31534. [PMID: 27530145 DOI: 10.1038/srep31534] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 0.5] [Reference Citation Analysis]
32 Iacobini C, Menini S, Ricci C, Scipioni A, Sansoni V, Mazzitelli G, Cordone S, Pesce C, Pugliese F, Pricci F, Pugliese G. Advanced lipoxidation end-products mediate lipid-induced glomerular injury: role of receptor-mediated mechanisms. J Pathol 2009;218:360-9. [PMID: 19334049 DOI: 10.1002/path.2536] [Cited by in Crossref: 51] [Cited by in F6Publishing: 50] [Article Influence: 3.9] [Reference Citation Analysis]
33 Zorov DB, Juhaszova M, Sollott SJ. Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release. Physiol Rev. 2014;94:909-950. [PMID: 24987008 DOI: 10.1152/physrev.00026.2013] [Cited by in Crossref: 1518] [Cited by in F6Publishing: 1418] [Article Influence: 189.8] [Reference Citation Analysis]
34 ALTamimi JZ, AlFaris NA, Al-Farga AM, Alshammari GM, BinMowyna MN, Yahya MA. Curcumin reverses diabetic nephropathy in streptozotocin-induced diabetes in rats by inhibition of PKCβ/p66Shc axis and activation of FOXO-3a. J Nutr Biochem 2021;87:108515. [PMID: 33017608 DOI: 10.1016/j.jnutbio.2020.108515] [Cited by in Crossref: 5] [Cited by in F6Publishing: 5] [Article Influence: 2.5] [Reference Citation Analysis]
35 Tomilov A, Allen S, Hui CK, Bettaieb A, Cortopassi G. Idebenone is a cytoprotective insulin sensitizer whose mechanism is Shc inhibition. Pharmacol Res 2018;137:89-103. [PMID: 30290222 DOI: 10.1016/j.phrs.2018.09.024] [Cited by in Crossref: 11] [Cited by in F6Publishing: 10] [Article Influence: 2.8] [Reference Citation Analysis]
36 Di Lisa F, Giorgio M, Ferdinandy P, Schulz R. New aspects of p66Shc in ischaemia reperfusion injury and other cardiovascular diseases. Br J Pharmacol 2017;174:1690-703. [PMID: 26990284 DOI: 10.1111/bph.13478] [Cited by in Crossref: 35] [Cited by in F6Publishing: 38] [Article Influence: 5.8] [Reference Citation Analysis]
37 Shin HJ, Park H, Shin N, Shin J, Gwon DH, Kwon HH, Yin Y, Hwang JA, Hong J, Heo JY, Kim CS, Joo Y, Kim Y, Kim J, Beom J, Kim DW. p66shc siRNA Nanoparticles Ameliorate Chondrocytic Mitochondrial Dysfunction in Osteoarthritis. Int J Nanomedicine 2020;15:2379-90. [PMID: 32308389 DOI: 10.2147/IJN.S234198] [Cited by in Crossref: 9] [Cited by in F6Publishing: 4] [Article Influence: 4.5] [Reference Citation Analysis]
38 Zhang C, Dong WB, Zhao S, Li QP, Kang L, Lei XP, Guo L, Zhai XS. Construction of p66Shc gene interfering lentivirus vectors and its effects on alveolar epithelial cells apoptosis induced by hyperoxia. Drug Des Devel Ther 2016;10:2611-22. [PMID: 27574400 DOI: 10.2147/DDDT.S84820] [Cited by in Crossref: 2] [Article Influence: 0.3] [Reference Citation Analysis]
39 Gorin Y, Wauquier F. Upstream regulators and downstream effectors of NADPH oxidases as novel therapeutic targets for diabetic kidney disease. Mol Cells 2015;38:285-96. [PMID: 25824546 DOI: 10.14348/molcells.2015.0010] [Cited by in Crossref: 9] [Cited by in F6Publishing: 21] [Article Influence: 1.3] [Reference Citation Analysis]
40 Wright KD, Staruschenko A, Sorokin A. Role of adaptor protein p66Shc in renal pathologies. Am J Physiol Renal Physiol 2018;314:F143-53. [PMID: 28978535 DOI: 10.1152/ajprenal.00414.2017] [Cited by in Crossref: 13] [Cited by in F6Publishing: 15] [Article Influence: 2.6] [Reference Citation Analysis]
41 Zheng D, Tao M, Liang X, Li Y, Jin J, He Q. p66Shc regulates podocyte autophagy in high glucose environment through the Notch-PTEN-PI3K/Akt/mTOR pathway. Histol Histopathol 2020;35:405-15. [PMID: 31650524 DOI: 10.14670/HH-18-178] [Cited by in F6Publishing: 4] [Reference Citation Analysis]
42 Tomilov A, Bettaieb A, Kim K, Sahdeo S, Tomilova N, Lam A, Hagopian K, Connell M, Fong J, Rowland D, Griffey S, Ramsey J, Haj F, Cortopassi G. Shc depletion stimulates brown fat activity in vivo and in vitro. Aging Cell 2014;13:1049-58. [PMID: 25257068 DOI: 10.1111/acel.12267] [Cited by in Crossref: 11] [Cited by in F6Publishing: 13] [Article Influence: 1.4] [Reference Citation Analysis]
43 Granatiero V, Gherardi G, Vianello M, Salerno E, Zecchini E, Toniolo L, Pallafacchina G, Murgia M, Blaauw B, Rizzuto R, Mammucari C. Role of p66shc in skeletal muscle function. Sci Rep 2017;7:6283. [PMID: 28740219 DOI: 10.1038/s41598-017-06363-0] [Cited by in Crossref: 7] [Cited by in F6Publishing: 7] [Article Influence: 1.4] [Reference Citation Analysis]
44 Zanetti M, Barazzoni R, Gortan Cappellari G, Burekovic I, Bosutti A, Stocca A, Bianco F, Ianche M, Panzetta G, Guarnieri G. Hemodialysis induces p66(shc) gene expression in nondiabetic humans: correlations with oxidative stress and systemic inflammation. J Ren Nutr 2011;21:401-9. [PMID: 21439852 DOI: 10.1053/j.jrn.2010.12.006] [Cited by in Crossref: 6] [Cited by in F6Publishing: 6] [Article Influence: 0.5] [Reference Citation Analysis]
45 Magenta A, Greco S, Capogrossi MC, Gaetano C, Martelli F. Nitric oxide, oxidative stress, and p66Shc interplay in diabetic endothelial dysfunction. Biomed Res Int 2014;2014:193095. [PMID: 24734227 DOI: 10.1155/2014/193095] [Cited by in Crossref: 48] [Cited by in F6Publishing: 47] [Article Influence: 6.0] [Reference Citation Analysis]
46 Iacobini C, Menini S, Blasetti Fantauzzi C, Pesce CM, Giaccari A, Salomone E, Lapolla A, Orioli M, Aldini G, Pugliese G. FL-926-16, a novel bioavailable carnosinase-resistant carnosine derivative, prevents onset and stops progression of diabetic nephropathy in db/db mice. Br J Pharmacol 2018;175:53-66. [PMID: 29053168 DOI: 10.1111/bph.14070] [Cited by in Crossref: 18] [Cited by in F6Publishing: 21] [Article Influence: 3.6] [Reference Citation Analysis]
47 Small DM, Coombes JS, Bennett N, Johnson DW, Gobe GC. Oxidative stress, anti-oxidant therapies and chronic kidney disease. Nephrology (Carlton). 2012;17:311-321. [PMID: 22288610 DOI: 10.1111/j.1440-1797.2012.01572.x] [Cited by in Crossref: 264] [Cited by in F6Publishing: 242] [Article Influence: 26.4] [Reference Citation Analysis]
48 Menini S, Iacobini C, Ricci C, Fantauzzi CB, Pugliese G. Protection from diabetes-induced atherosclerosis and renal disease by d-carnosine-octylester: effects of early vs late inhibition of advanced glycation end-products in Apoe-null mice. Diabetologia 2015;58:845-53. [DOI: 10.1007/s00125-014-3467-6] [Cited by in Crossref: 44] [Cited by in F6Publishing: 39] [Article Influence: 5.5] [Reference Citation Analysis]
49 Hartmann P, Fet N, Garab D, Szabó A, Kaszaki J, Srinivasan PK, Tolba RH, Boros M. L-alpha-glycerylphosphorylcholine reduces the microcirculatory dysfunction and nicotinamide adenine dinucleotide phosphate-oxidase type 4 induction after partial hepatic ischemia in rats. Journal of Surgical Research 2014;189:32-40. [DOI: 10.1016/j.jss.2013.12.025] [Cited by in Crossref: 9] [Cited by in F6Publishing: 8] [Article Influence: 1.1] [Reference Citation Analysis]
50 Menini S, Iacobini C, Pugliese G, Pesce C. Dietary interventions to contrast the onset and progression of diabetic nephropathy: A critical survey of new data. Crit Rev Food Sci Nutr 2018;58:1671-80. [PMID: 28128635 DOI: 10.1080/10408398.2016.1278355] [Cited by in Crossref: 5] [Cited by in F6Publishing: 4] [Article Influence: 1.0] [Reference Citation Analysis]
51 Serban AI, Stanca L, Geicu OI, Munteanu MC, Costache M, Dinischiotu A. Extracellular matrix is modulated in advanced glycation end products milieu via a RAGE receptor dependent pathway boosted by transforming growth factor-β1 RAGE. J Diabetes 2015;7:114-24. [PMID: 24666836 DOI: 10.1111/1753-0407.12154] [Cited by in Crossref: 21] [Cited by in F6Publishing: 23] [Article Influence: 2.6] [Reference Citation Analysis]