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For: Sherman MH, Yu RT, Engle DD, Ding N, Atkins AR, Tiriac H, Collisson EA, Connor F, Van Dyke T, Kozlov S, Martin P, Tseng TW, Dawson DW, Donahue TR, Masamune A, Shimosegawa T, Apte MV, Wilson JS, Ng B, Lau SL, Gunton JE, Wahl GM, Hunter T, Drebin JA, O'Dwyer PJ, Liddle C, Tuveson DA, Downes M, Evans RM. Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy. Cell. 2014;159:80-93. [PMID: 25259922 DOI: 10.1016/j.cell.2014.08.007] [Cited by in Crossref: 560] [Cited by in F6Publishing: 520] [Article Influence: 80.0] [Reference Citation Analysis]
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6 Hesler RA, Huang JJ, Starr MD, Treboschi VM, Bernanke AG, Nixon AB, McCall SJ, White RR, Blobe GC. TGF-β-induced stromal CYR61 promotes resistance to gemcitabine in pancreatic ductal adenocarcinoma through downregulation of the nucleoside transporters hENT1 and hCNT3. Carcinogenesis 2016;37:1041-51. [PMID: 27604902 DOI: 10.1093/carcin/bgw093] [Cited by in Crossref: 39] [Cited by in F6Publishing: 37] [Article Influence: 7.8] [Reference Citation Analysis]
7 Kong F, Li L, Wang G, Deng X, Li Z, Kong X. VDR signaling inhibits cancer-associated-fibroblasts' release of exosomal miR-10a-5p and limits their supportive effects on pancreatic cancer cells. Gut 2019;68:950-1. [PMID: 29695492 DOI: 10.1136/gutjnl-2018-316627] [Cited by in Crossref: 17] [Cited by in F6Publishing: 20] [Article Influence: 4.3] [Reference Citation Analysis]
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10 Shepard HM. Breaching the Castle Walls: Hyaluronan Depletion as a Therapeutic Approach to Cancer Therapy. Front Oncol. 2015;5:192. [PMID: 26380222 DOI: 10.3389/fonc.2015.00192] [Cited by in Crossref: 43] [Cited by in F6Publishing: 40] [Article Influence: 6.1] [Reference Citation Analysis]
11 Chaurasiya S, Kim SI, O'Leary M, Park AK, Lu J, Kang S, Zhang Z, Yang A, Woo Y, Fong Y, Warner SG. Toward comprehensive imaging of oncolytic viroimmunotherapy. Mol Ther Oncolytics 2021;23:303-10. [PMID: 34786474 DOI: 10.1016/j.omto.2021.06.010] [Reference Citation Analysis]
12 Xia SH. Prospect and clinical value of oxymatrine in prevention and treatment of pancreatic fibrosis. Shijie Huaren Xiaohua Zazhi 2020; 28(17): 819-826 [DOI: 10.11569/wcjd.v28.i17.819] [Reference Citation Analysis]
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14 Ko YC, Lai TY, Hsu SC, Wang FH, Su SY, Chen YL, Tsai ML, Wu CC, Hsiao JR, Chang JY, Wu YM, Robinson DR, Lin CY, Lin SF. Index of Cancer-Associated Fibroblasts Is Superior to the Epithelial-Mesenchymal Transition Score in Prognosis Prediction. Cancers (Basel) 2020;12:E1718. [PMID: 32605311 DOI: 10.3390/cancers12071718] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
15 Broekgaarden M, Anbil S, Bulin AL, Obaid G, Mai Z, Baglo Y, Rizvi I, Hasan T. Modulation of redox metabolism negates cancer-associated fibroblasts-induced treatment resistance in a heterotypic 3D culture platform of pancreatic cancer. Biomaterials 2019;222:119421. [PMID: 31494503 DOI: 10.1016/j.biomaterials.2019.119421] [Cited by in Crossref: 24] [Cited by in F6Publishing: 22] [Article Influence: 8.0] [Reference Citation Analysis]
16 Fountzilas C, Javle M, Tan W, Ma Y, Fetterly G, Iyer R, Johnson C. A phase 1, open-label, dose escalation study of intravenous paricalcitol in combination with gemcitabine in patients with advanced malignancies. Cancer 2018;124:3890-9. [PMID: 30299542 DOI: 10.1002/cncr.31676] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 0.8] [Reference Citation Analysis]
17 Auciello FR, Bulusu V, Oon C, Tait-Mulder J, Berry M, Bhattacharyya S, Tumanov S, Allen-Petersen BL, Link J, Kendsersky ND, Vringer E, Schug M, Novo D, Hwang RF, Evans RM, Nixon C, Dorrell C, Morton JP, Norman JC, Sears RC, Kamphorst JJ, Sherman MH. A Stromal Lysolipid-Autotaxin Signaling Axis Promotes Pancreatic Tumor Progression. Cancer Discov 2019;9:617-27. [PMID: 30837243 DOI: 10.1158/2159-8290.CD-18-1212] [Cited by in Crossref: 78] [Cited by in F6Publishing: 47] [Article Influence: 26.0] [Reference Citation Analysis]
18 Cheng X, Xu X, Chen D, Zhao F, Wang W. Therapeutic potential of targeting the Wnt/β-catenin signaling pathway in colorectal cancer. Biomed Pharmacother 2019;110:473-81. [PMID: 30530050 DOI: 10.1016/j.biopha.2018.11.082] [Cited by in Crossref: 100] [Cited by in F6Publishing: 100] [Article Influence: 25.0] [Reference Citation Analysis]
19 Gerasimenko JV, Peng S, Tsugorka T, Gerasimenko OV. Ca2+ signalling underlying pancreatitis. Cell Calcium 2018;70:95-101. [PMID: 28552244 DOI: 10.1016/j.ceca.2017.05.010] [Cited by in Crossref: 22] [Cited by in F6Publishing: 20] [Article Influence: 4.4] [Reference Citation Analysis]
20 Kong B, Bruns P, Behler NA, Chang L, Schlitter AM, Cao J, Gewies A, Ruland J, Fritzsche S, Valkovskaya N, Jian Z, Regel I, Raulefs S, Irmler M, Beckers J, Friess H, Erkan M, Mueller NS, Roth S, Hackert T, Esposito I, Theis FJ, Kleeff J, Michalski CW. Dynamic landscape of pancreatic carcinogenesis reveals early molecular networks of malignancy. Gut 2018;67:146-56. [PMID: 27646934 DOI: 10.1136/gutjnl-2015-310913] [Cited by in Crossref: 26] [Cited by in F6Publishing: 22] [Article Influence: 4.3] [Reference Citation Analysis]
21 Sarper M, Cortes E, Lieberthal TJ, Del Río Hernández A. ATRA modulates mechanical activation of TGF-β by pancreatic stellate cells. Sci Rep 2016;6:27639. [PMID: 27375161 DOI: 10.1038/srep27639] [Cited by in Crossref: 42] [Cited by in F6Publishing: 42] [Article Influence: 7.0] [Reference Citation Analysis]
22 Tanaka HY, Kano MR. Stromal barriers to nanomedicine penetration in the pancreatic tumor microenvironment. Cancer Sci 2018;109:2085-92. [PMID: 29737600 DOI: 10.1111/cas.13630] [Cited by in Crossref: 37] [Cited by in F6Publishing: 33] [Article Influence: 9.3] [Reference Citation Analysis]
23 Maestro MA, Molnár F, Carlberg C. Vitamin D and Its Synthetic Analogs. J Med Chem 2019;62:6854-75. [PMID: 30916559 DOI: 10.1021/acs.jmedchem.9b00208] [Cited by in Crossref: 21] [Cited by in F6Publishing: 17] [Article Influence: 7.0] [Reference Citation Analysis]
24 Lee BY, Hogg EKJ, Below CR, Kononov A, Blanco-Gomez A, Heider F, Xu J, Hutton C, Zhang X, Scheidt T, Beattie K, Lamarca A, McNamara M, Valle JW, Jørgensen C. Heterocellular OSM-OSMR signalling reprograms fibroblasts to promote pancreatic cancer growth and metastasis. Nat Commun 2021;12:7336. [PMID: 34921158 DOI: 10.1038/s41467-021-27607-8] [Reference Citation Analysis]
25 Zhao C, Thompson BJ, Chen K, Gao F, Blouw B, Marella M, Zimmerman S, Kimbler T, Garrovillo S, Bahn J, Huang L, Huang Z, Shepard HM, Rosengren S, Thanos CD, Maneval DC. The growth of a xenograft breast cancer tumor model with engineered hyaluronan-accumulating stroma is dependent on hyaluronan and independent of CD44. Oncotarget 2019;10:6561-76. [PMID: 31762938 DOI: 10.18632/oncotarget.27302] [Cited by in Crossref: 3] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
26 Belhabib I, Zaghdoudi S, Lac C, Bousquet C, Jean C. Extracellular Matrices and Cancer-Associated Fibroblasts: Targets for Cancer Diagnosis and Therapy? Cancers (Basel) 2021;13:3466. [PMID: 34298680 DOI: 10.3390/cancers13143466] [Reference Citation Analysis]
27 Hu C, Yin L, Chen Z, Waldron RT, Lugea A, Lin Y, Zhai X, Wen L, Han YP, Pandol SJ, Deng L, Xia Q. The unique pancreatic stellate cell gene expression signatures are associated with the progression from acute to chronic pancreatitis. Comput Struct Biotechnol J 2021;19:6375-85. [PMID: 34938413 DOI: 10.1016/j.csbj.2021.11.031] [Reference Citation Analysis]
28 Fabris L, Perugorria MJ, Mertens J, Björkström NK, Cramer T, Lleo A, Solinas A, Sänger H, Lukacs-Kornek V, Moncsek A, Siebenhüner A, Strazzabosco M. The tumour microenvironment and immune milieu of cholangiocarcinoma. Liver Int 2019;39 Suppl 1:63-78. [PMID: 30907492 DOI: 10.1111/liv.14098] [Cited by in Crossref: 31] [Cited by in F6Publishing: 26] [Article Influence: 15.5] [Reference Citation Analysis]
29 Chen K, Zhang C, Ling S, Wei R, Wang J, Xu X. The metabolic flexibility of quiescent CSC: implications for chemotherapy resistance. Cell Death Dis 2021;12:835. [PMID: 34482364 DOI: 10.1038/s41419-021-04116-6] [Reference Citation Analysis]
30 Pfeifer E, Burchell JM, Dazzi F, Sarker D, Beatson R. Apoptosis in the Pancreatic Cancer Tumor Microenvironment-The Double-Edged Sword of Cancer-Associated Fibroblasts. Cells 2021;10:1653. [PMID: 34359823 DOI: 10.3390/cells10071653] [Reference Citation Analysis]
31 Masamune A, Shimosegawa T. Pancreatic stellate cells: A dynamic player of the intercellular communication in pancreatic cancer. Clin Res Hepatol Gastroenterol 2015;39 Suppl 1:S98-103. [PMID: 26189983 DOI: 10.1016/j.clinre.2015.05.018] [Cited by in Crossref: 21] [Cited by in F6Publishing: 15] [Article Influence: 3.0] [Reference Citation Analysis]
32 Winograd R, Byrne KT, Evans RA, Odorizzi PM, Meyer AR, Bajor DL, Clendenin C, Stanger BZ, Furth EE, Wherry EJ, Vonderheide RH. Induction of T-cell Immunity Overcomes Complete Resistance to PD-1 and CTLA-4 Blockade and Improves Survival in Pancreatic Carcinoma. Cancer Immunol Res. 2015;3:399-411. [PMID: 25678581 DOI: 10.1158/2326-6066.cir-14-0215] [Cited by in Crossref: 242] [Cited by in F6Publishing: 171] [Article Influence: 34.6] [Reference Citation Analysis]
33 Yuan C, Qian ZR, Babic A, Morales-Oyarvide V, Rubinson DA, Kraft P, Ng K, Bao Y, Giovannucci EL, Ogino S, Stampfer MJ, Gaziano JM, Sesso HD, Buring JE, Cochrane BB, Chlebowski RT, Snetselaar LG, Manson JE, Fuchs CS, Wolpin BM. Prediagnostic Plasma 25-Hydroxyvitamin D and Pancreatic Cancer Survival. J Clin Oncol. 2016;34:2899-2905. [PMID: 27325858 DOI: 10.1200/jco.2015.66.3005] [Cited by in Crossref: 30] [Cited by in F6Publishing: 19] [Article Influence: 5.0] [Reference Citation Analysis]
34 Von Hoff DD, Cridebring D, Tian OY, Han H, Bhore R, Franco T, Ondovik MS, Louis CU. Analysis of the Role of Plasma 25-Hydroxyvitamin D Levels in Survival Outcomes in Patients from the Phase III MPACT Trial of Metastatic Pancreatic Cancer. Oncologist 2021;26:e704-9. [PMID: 33345430 DOI: 10.1002/onco.13645] [Reference Citation Analysis]
35 Elangovan H, Chahal S, Gunton JE. Vitamin D in liver disease: Current evidence and potential directions.Biochim Biophys Acta Mol Basis Dis. 2017;1863:907-916. [PMID: 28064017 DOI: 10.1016/j.bbadis.2017.01.001] [Cited by in Crossref: 23] [Cited by in F6Publishing: 21] [Article Influence: 4.6] [Reference Citation Analysis]
36 Northey JJ, Przybyla L, Weaver VM. Tissue Force Programs Cell Fate and Tumor Aggression. Cancer Discov. 2017;7:1224-1237. [PMID: 29038232 DOI: 10.1158/2159-8290.CD-16-0733] [Cited by in Crossref: 107] [Cited by in F6Publishing: 60] [Article Influence: 21.4] [Reference Citation Analysis]
37 Chiavarina B, Ronca R, Otaka Y, Sutton RB, Rezzola S, Yokobori T, Chiodelli P, Souche R, Pourquier D, Maraver A, Faa G, Khellaf L, Turtoi E, Oyama T, Gofflot S, Bellahcène A, Detry O, Delvenne P, Castronovo V, Nishiyama M, Turtoi A. Fibroblast-derived prolargin is a tumor suppressor in hepatocellular carcinoma. Oncogene 2022. [PMID: 35031773 DOI: 10.1038/s41388-021-02171-z] [Reference Citation Analysis]
38 Orozco CA, Martinez-Bosch N, Guerrero PE, Vinaixa J, Dalotto-Moreno T, Iglesias M, Moreno M, Djurec M, Poirier F, Gabius HJ, Fernandez-Zapico ME, Hwang RF, Guerra C, Rabinovich GA, Navarro P. Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor-stroma crosstalk. Proc Natl Acad Sci U S A 2018;115:E3769-78. [PMID: 29615514 DOI: 10.1073/pnas.1722434115] [Cited by in Crossref: 50] [Cited by in F6Publishing: 54] [Article Influence: 12.5] [Reference Citation Analysis]
39 Wu F, Yang J, Liu J, Wang Y, Mu J, Zeng Q, Deng S, Zhou H. Signaling pathways in cancer-associated fibroblasts and targeted therapy for cancer. Signal Transduct Target Ther 2021;6:218. [PMID: 34108441 DOI: 10.1038/s41392-021-00641-0] [Cited by in Crossref: 1] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
40 Hosein AN, Brekken RA, Maitra A. Pancreatic cancer stroma: an update on therapeutic targeting strategies. Nat Rev Gastroenterol Hepatol 2020;17:487-505. [PMID: 32393771 DOI: 10.1038/s41575-020-0300-1] [Cited by in Crossref: 75] [Cited by in F6Publishing: 79] [Article Influence: 37.5] [Reference Citation Analysis]
41 Sahai E, Astsaturov I, Cukierman E, DeNardo DG, Egeblad M, Evans RM, Fearon D, Greten FR, Hingorani SR, Hunter T, Hynes RO, Jain RK, Janowitz T, Jorgensen C, Kimmelman AC, Kolonin MG, Maki RG, Powers RS, Puré E, Ramirez DC, Scherz-Shouval R, Sherman MH, Stewart S, Tlsty TD, Tuveson DA, Watt FM, Weaver V, Weeraratna AT, Werb Z. A framework for advancing our understanding of cancer-associated fibroblasts. Nat Rev Cancer 2020;20:174-86. [PMID: 31980749 DOI: 10.1038/s41568-019-0238-1] [Cited by in Crossref: 447] [Cited by in F6Publishing: 455] [Article Influence: 223.5] [Reference Citation Analysis]
42 Annu K, Cline C, Yasuda K, Ganguly S, Pesch A, Cooper B, Janke L, Payton M, Mukherjee K, Surman SL, Hurwitz JL, Schuetz EG. Role of Vitamins A and D in BCR-ABL Arf-/- Acute Lymphoblastic Leukemia. Sci Rep 2020;10:2359. [PMID: 32047189 DOI: 10.1038/s41598-020-59101-4] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
43 Gryshchenko O, Gerasimenko JV, Gerasimenko OV, Petersen OH. Ca(2+) signals mediated by bradykinin type 2 receptors in normal pancreatic stellate cells can be inhibited by specific Ca(2+) channel blockade. J Physiol 2016;594:281-93. [PMID: 26442817 DOI: 10.1113/JP271468] [Cited by in Crossref: 32] [Cited by in F6Publishing: 21] [Article Influence: 4.6] [Reference Citation Analysis]
44 Kota J, Hancock J, Kwon J, Korc M. Pancreatic cancer: Stroma and its current and emerging targeted therapies. Cancer Lett. 2017;391:38-49. [PMID: 28093284 DOI: 10.1016/j.canlet.2016.12.035] [Cited by in Crossref: 83] [Cited by in F6Publishing: 81] [Article Influence: 16.6] [Reference Citation Analysis]
45 Chen M, Mao A, Xu M, Weng Q, Mao J, Ji J. CRISPR-Cas9 for cancer therapy: Opportunities and challenges. Cancer Letters 2019;447:48-55. [DOI: 10.1016/j.canlet.2019.01.017] [Cited by in Crossref: 33] [Cited by in F6Publishing: 32] [Article Influence: 11.0] [Reference Citation Analysis]
46 Kleeff J, Korc M, Apte M, La Vecchia C, Johnson CD, Biankin AV, Neale RE, Tempero M, Tuveson DA, Hruban RH, Neoptolemos JP. Pancreatic cancer. Nat Rev Dis Primers. 2016;2:16022. [PMID: 27158978 DOI: 10.1038/nrdp.2016.22] [Cited by in Crossref: 657] [Cited by in F6Publishing: 617] [Article Influence: 109.5] [Reference Citation Analysis]
47 D'Arcangelo E, Wu NC, Cadavid JL, McGuigan AP. The life cycle of cancer-associated fibroblasts within the tumour stroma and its importance in disease outcome. Br J Cancer 2020;122:931-42. [PMID: 31992854 DOI: 10.1038/s41416-019-0705-1] [Cited by in Crossref: 19] [Cited by in F6Publishing: 17] [Article Influence: 9.5] [Reference Citation Analysis]
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49 Xia G, Zhang H, Cheng R, Wang H, Song Z, Deng L, Huang X, Santos HA, Cui W. Localized Controlled Delivery of Gemcitabine via Microsol Electrospun Fibers to Prevent Pancreatic Cancer Recurrence. Adv Healthcare Mater 2018;7:1800593. [DOI: 10.1002/adhm.201800593] [Cited by in Crossref: 20] [Cited by in F6Publishing: 17] [Article Influence: 5.0] [Reference Citation Analysis]
50 Aggarwal A, Feldman D, Feldman BJ. Identification of tumor-autonomous and indirect effects of vitamin D action that inhibit breast cancer growth and tumor progression. J Steroid Biochem Mol Biol 2018;177:155-8. [PMID: 28710021 DOI: 10.1016/j.jsbmb.2017.07.003] [Cited by in Crossref: 6] [Cited by in F6Publishing: 7] [Article Influence: 1.2] [Reference Citation Analysis]
51 Mei L, Du W, Ma WW. Targeting stromal microenvironment in pancreatic ductal adenocarcinoma: controversies and promises. J Gastrointest Oncol. 2016;7:487-494. [PMID: 27284483 DOI: 10.21037/jgo.2016.03.03] [Cited by in Crossref: 30] [Cited by in F6Publishing: 28] [Article Influence: 5.0] [Reference Citation Analysis]
52 Yoshida GJ, Azuma A, Miura Y, Orimo A. Activated Fibroblast Program Orchestrates Tumor Initiation and Progression; Molecular Mechanisms and the Associated Therapeutic Strategies. Int J Mol Sci 2019;20:E2256. [PMID: 31067787 DOI: 10.3390/ijms20092256] [Cited by in Crossref: 54] [Cited by in F6Publishing: 50] [Article Influence: 18.0] [Reference Citation Analysis]
53 Yang S, Lin J. Effect of vitamin D3 derivative MART-10 on cell growth and expression of survivin mRNA, c-myc protein and P21 protein in BxPC-3 cells. Shijie Huaren Xiaohua Zazhi 2016; 24(12): 1860-1865 [DOI: 10.11569/wcjd.v24.i12.1860] [Reference Citation Analysis]
54 Bhaw-Luximon A, Jhurry D. New avenues for improving pancreatic ductal adenocarcinoma (PDAC) treatment: Selective stroma depletion combined with nano drug delivery. Cancer Lett. 2015;369:266-273. [PMID: 26415628 DOI: 10.1016/j.canlet.2015.09.007] [Cited by in Crossref: 33] [Cited by in F6Publishing: 33] [Article Influence: 4.7] [Reference Citation Analysis]
55 Wang L, Liu Z, Zhou Q, Gu S, Liu X, Huang J, Jiang H, Wang H, Cao L, Sun J, Shen Y, Meng H, Liu X. Prodrug nanoparticles rationally integrating stroma modification and chemotherapy to treat metastatic pancreatic cancer. Biomaterials 2021;278:121176. [PMID: 34656882 DOI: 10.1016/j.biomaterials.2021.121176] [Reference Citation Analysis]
56 Capuani F, De Martino D, Marinari E, De Martino A. Quantitative constraint-based computational model of tumor-to-stroma coupling via lactate shuttle. Sci Rep 2015;5:11880. [PMID: 26149467 DOI: 10.1038/srep11880] [Cited by in Crossref: 12] [Cited by in F6Publishing: 10] [Article Influence: 1.7] [Reference Citation Analysis]
57 Lee YT, Tan YJ, Falasca M, Oon CE. Cancer-Associated Fibroblasts: Epigenetic Regulation and Therapeutic Intervention in Breast Cancer. Cancers (Basel) 2020;12:E2949. [PMID: 33066013 DOI: 10.3390/cancers12102949] [Cited by in Crossref: 6] [Cited by in F6Publishing: 6] [Article Influence: 3.0] [Reference Citation Analysis]
58 Kumar K, DeCant BT, Grippo PJ, Hwang RF, Bentrem DJ, Ebine K, Munshi HG. BET inhibitors block pancreatic stellate cell collagen I production and attenuate fibrosis in vivo. JCI Insight 2017;2:e88032. [PMID: 28194432 DOI: 10.1172/jci.insight.88032] [Cited by in Crossref: 31] [Cited by in F6Publishing: 27] [Article Influence: 6.2] [Reference Citation Analysis]
59 Liu Q, Zhang J, Jiang M, Zhang Y, Chen T, Zhang J, Li B, Chen J, Xing W. Evaluating the Histopathology of Pancreatic Ductal Adenocarcinoma by Intravoxel Incoherent Motion-Diffusion Weighted Imaging Comparing With Diffusion-Weighted Imaging. Front Oncol 2021;11:670085. [PMID: 34249707 DOI: 10.3389/fonc.2021.670085] [Reference Citation Analysis]
60 Gong J, Hendifar A, Tuli R, Chuang J, Cho M, Chung V, Li D, Salgia R. Combination systemic therapies with immune checkpoint inhibitors in pancreatic cancer: overcoming resistance to single-agent checkpoint blockade. Clin Transl Med 2018;7:32. [PMID: 30294755 DOI: 10.1186/s40169-018-0210-9] [Cited by in Crossref: 13] [Cited by in F6Publishing: 12] [Article Influence: 3.3] [Reference Citation Analysis]
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