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For: Qu H, Liu Y, Bi DS. Clinical risk factors for anastomotic leakage after laparoscopic anterior resection for rectal cancer: a systematic review and meta-analysis. Surg Endosc. 2015;29:3608-3617. [PMID: 25743996 DOI: 10.1007/s00464-015-4117-x] [Cited by in Crossref: 92] [Cited by in F6Publishing: 81] [Article Influence: 13.1] [Reference Citation Analysis]
Number Citing Articles
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5 Goto S, Hasegawa S, Hata H, Yamaguchi T, Hida K, Nishitai R, Yamanokuchi S, Nomura A, Yamanaka T, Sakai Y. Differences in surgical site infection between laparoscopic colon and rectal surgeries: sub-analysis of a multicenter randomized controlled trial (Japan-Multinational Trial Organization PREV 07-01). Int J Colorectal Dis 2016;31:1775-84. [PMID: 27604812 DOI: 10.1007/s00384-016-2643-1] [Cited by in Crossref: 10] [Cited by in F6Publishing: 10] [Article Influence: 1.7] [Reference Citation Analysis]
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7 Sciuto A, Merola G, De Palma GD, Sodo M, Pirozzi F, Bracale UM, Bracale U. Predictive factors for anastomotic leakage after laparoscopic colorectal surgery. World J Gastroenterol 2018; 24(21): 2247-2260 [PMID: 29881234 DOI: 10.3748/wjg.v24.i21.2247] [Cited by in CrossRef: 84] [Cited by in F6Publishing: 65] [Article Influence: 21.0] [Reference Citation Analysis]
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9 Zarnescu EC, Zarnescu NO, Costea R. Updates of Risk Factors for Anastomotic Leakage after Colorectal Surgery. Diagnostics (Basel) 2021;11:2382. [PMID: 34943616 DOI: 10.3390/diagnostics11122382] [Reference Citation Analysis]
10 Nishizawa Y, Nishigori H, Tsukada Y, Sasaki T, Tsukamoto S, Kanemitsu Y, Nakano D, Yamaguchi T, Otsuka K, Nakamura T, Shiomi A, Iwasaki N, Tamura H, Wakabayashi M, Nomura S, Ito M. A multicentre confirmatory single-arm trial of the safety and efficacy of a transanal drain for prevention of anastomotic leakage after surgery for rectal cancer. Colorectal Dis 2021. [PMID: 34379874 DOI: 10.1111/codi.15869] [Reference Citation Analysis]
11 Brind'Amour A, Pravong V, Sidéris L, Dubé P, De Guerke L, Fortin S, Auclair MH, Trilling B, Tremblay JF. Rectal anastomosis and hyperthermic intraperitoneal chemotherapy: Should we avoid diverting loop ileostomy? Eur J Surg Oncol 2021;47:2346-51. [PMID: 33637373 DOI: 10.1016/j.ejso.2021.02.017] [Reference Citation Analysis]
12 Ganapathi SK, Subbiah R, Rudramurthy S, Kakkilaya H, Ramakrishnan P, Chinnusamy P. Laparoscopic anterior resection: Analysis of technique over 1000 cases. J Minim Access Surg 2021;17:356-62. [PMID: 33605924 DOI: 10.4103/jmas.JMAS_132_20] [Reference Citation Analysis]
13 Luo Y, Liu Z, Ye P, Fu Z, Lu F, Suleiman AA, Liao J, Xiao J. Safety and efficacy of intraoperative iodine-125 seed implantation brachytherapy for rectal cancer patients: A retrospective clinical research: A retrospective clinical research. Journal of Gastroenterology and Hepatology 2016;31:1076-84. [DOI: 10.1111/jgh.13261] [Cited by in Crossref: 7] [Cited by in F6Publishing: 5] [Article Influence: 1.2] [Reference Citation Analysis]
14 Peltrini R, Imperatore N, Carannante F, Cuccurullo D, Capolupo GT, Bracale U, Caricato M, Corcione F. Age and comorbidities do not affect short-term outcomes after laparoscopic rectal cancer resection in elderly patients. A multi-institutional cohort study in 287 patients. Updates Surg 2021;73:527-37. [PMID: 33586089 DOI: 10.1007/s13304-021-00990-z] [Cited by in Crossref: 1] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
15 Bi L, Deng X, Meng X, Yang X, Wei M, Wu Q, Ren M, Wang Z. Ligating the rectum with cable tie facilitates rectum transection in laparoscopic anterior resection of rectal cancer. Langenbecks Arch Surg 2020;405:233-9. [PMID: 32266529 DOI: 10.1007/s00423-020-01863-6] [Cited by in Crossref: 1] [Article Influence: 0.5] [Reference Citation Analysis]
16 Hasegawa H, Tsukada Y, Wakabayashi M, Nomura S, Sasaki T, Nishizawa Y, Ikeda K, Akimoto T, Ito M. Impact of intraoperative indocyanine green fluorescence angiography on anastomotic leakage after laparoscopic sphincter-sparing surgery for malignant rectal tumors. Int J Colorectal Dis 2020;35:471-80. [DOI: 10.1007/s00384-019-03490-0] [Cited by in Crossref: 15] [Cited by in F6Publishing: 14] [Article Influence: 7.5] [Reference Citation Analysis]
17 Bo T, Chuan L, Hongchang L, Chao Z, Huaxing L, Peiwu Y. Robotic versus laparoscopic rectal resection surgery: Short-term outcomes and complications: A retrospective comparative study. Surg Oncol 2019;29:71-7. [PMID: 31196497 DOI: 10.1016/j.suronc.2019.02.004] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 2.0] [Reference Citation Analysis]
18 Tejedor P, Sagias F, Flashman K, Kandala NL, Khan J. The use of robotic or laparoscopic stapler in rectal cancer surgery: a systematic review and meta-analysis. J Robot Surg 2020;14:829-33. [PMID: 32691353 DOI: 10.1007/s11701-020-01126-y] [Cited by in Crossref: 1] [Article Influence: 0.5] [Reference Citation Analysis]
19 Shen Z, An Y, Shi Y, Yin M, Xie Q, Gao Z, Jiang K, Wang S, Ye Y. The Aortic Calcification Index is a risk factor associated with anastomotic leakage after anterior resection of rectal cancer. Colorectal Dis 2019;21:1397-404. [PMID: 31361381 DOI: 10.1111/codi.14795] [Cited by in Crossref: 5] [Cited by in F6Publishing: 3] [Article Influence: 1.7] [Reference Citation Analysis]
20 Liu D, Liang L, Liu L, Zhu Z. Does intraoperative indocyanine green fluorescence angiography decrease the incidence of anastomotic leakage in colorectal surgery? A systematic review and meta-analysis. Int J Colorectal Dis 2021;36:57-66. [DOI: 10.1007/s00384-020-03741-5] [Cited by in Crossref: 10] [Cited by in F6Publishing: 6] [Article Influence: 5.0] [Reference Citation Analysis]
21 Chaouch MA, Kellil T, Jeddi C, Saidani A, Chebbi F, Zouari K. How to Prevent Anastomotic Leak in Colorectal Surgery? A Systematic Review. Ann Coloproctol 2020;36:213-22. [PMID: 32919437 DOI: 10.3393/ac.2020.05.14.2] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
22 Portale G, Popesc GO, Parotto M, Cavallin F. Delayed Colo-anal Anastomosis for Rectal Cancer: Pelvic Morbidity, Functional Results and Oncological Outcomes: A Systematic Review. World J Surg 2019;43:1360-9. [PMID: 30690655 DOI: 10.1007/s00268-019-04918-y] [Cited by in Crossref: 9] [Cited by in F6Publishing: 6] [Article Influence: 3.0] [Reference Citation Analysis]
23 Iwama N, Tsuruta M, Hasegawa H, Okabayashi K, Ishida T, Kitagawa Y. Relationship between anastomotic leakage and CT value of the mesorectum in laparoscopic anterior resection for rectal cancer. Jpn J Clin Oncol 2020;50:405-10. [PMID: 31829424 DOI: 10.1093/jjco/hyz192] [Reference Citation Analysis]
24 Brescia A, Pezzatini M, Romeo G, Cinquepalmi M, Pindozzi F, Dall’oglio A, Gasparrini M, Lazar F. Indocyanine green fluorescence angiography: a new ERAS item. Updates Surg 2018;70:427-32. [DOI: 10.1007/s13304-018-0590-9] [Cited by in Crossref: 8] [Cited by in F6Publishing: 7] [Article Influence: 2.0] [Reference Citation Analysis]
25 Iwamoto M, Kawada K, Hida K, Hasegawa S, Sakai Y. Delayed anastomotic leakage following laparoscopic intersphincteric resection for lower rectal cancer: report of four cases and literature review. World J Surg Oncol 2017;15:143. [PMID: 28764707 DOI: 10.1186/s12957-017-1208-2] [Cited by in Crossref: 4] [Cited by in F6Publishing: 2] [Article Influence: 0.8] [Reference Citation Analysis]
26 Liu J, Zheng L, Ren S, Zuo S, Zhang J, Wan Y, Wang X, Tang J. Nomogram for Predicting the Probability of Permanent Stoma after Laparoscopic Intersphincteric Resection. J Gastrointest Surg 2021. [PMID: 33904057 DOI: 10.1007/s11605-021-04982-7] [Reference Citation Analysis]
27 Wada T, Kawada K, Hoshino N, Inamoto S, Yoshitomi M, Hida K, Sakai Y. The effects of intraoperative ICG fluorescence angiography in laparoscopic low anterior resection: a propensity score-matched study. Int J Clin Oncol 2019;24:394-402. [DOI: 10.1007/s10147-018-1365-5] [Cited by in Crossref: 26] [Cited by in F6Publishing: 24] [Article Influence: 6.5] [Reference Citation Analysis]
28 Lee SY, Jung MR, Kim CH, Kim YJ, Kim HR. Nutritional risk screening score is an independent predictive factor of anastomotic leakage after rectal cancer surgery. Eur J Clin Nutr 2018;72:489-95. [PMID: 29459787 DOI: 10.1038/s41430-018-0112-3] [Cited by in Crossref: 10] [Cited by in F6Publishing: 8] [Article Influence: 2.5] [Reference Citation Analysis]
29 Guadagni S, Di Franco G, Gianardi D, Palmeri M, Ceccarelli C, Bianchini M, Furbetta N, Caprili G, D'Isidoro C, Moglia A, Melfi F, Buccianti P, Mosca F, Morelli L. Control Comparison of the New EndoWrist and Traditional Laparoscopic Staplers for Anterior Rectal Resection with the Da Vinci Xi: A Case Study. J Laparoendosc Adv Surg Tech A 2018;28:1422-7. [PMID: 29920142 DOI: 10.1089/lap.2018.0218] [Cited by in Crossref: 6] [Cited by in F6Publishing: 3] [Article Influence: 1.5] [Reference Citation Analysis]
30 Emile SH, Abd El-Hamed TM. Routine Drainage of Colorectal Anastomoses: An Evidence-Based Review of the Current Literature. Gastroenterol Res Pract 2017;2017:6253898. [PMID: 29158731 DOI: 10.1155/2017/6253898] [Cited by in Crossref: 10] [Cited by in F6Publishing: 8] [Article Influence: 2.0] [Reference Citation Analysis]
31 Zhou C, Wu XR, Liu XH, Chen YF, Ke J, He XW, He XS, Hu T, Zou YF, Zheng XB, Liu HS, Hu JC, Wu XJ, Wang JP, Lan P. Male gender is associated with an increased risk of anastomotic leak in rectal cancer patients after total mesorectal excision. Gastroenterol Rep (Oxf) 2018;6:137-43. [PMID: 29780603 DOI: 10.1093/gastro/gox039] [Cited by in Crossref: 6] [Cited by in F6Publishing: 4] [Article Influence: 1.5] [Reference Citation Analysis]
32 Rutgers MLW, Bemelman WA, Khan JS, Hompes R. The role of transanal total mesorectal excision. Surg Oncol 2021;:101695. [PMID: 34924223 DOI: 10.1016/j.suronc.2021.101695] [Reference Citation Analysis]
33 Barrios P, Ramos I, Crusellas O, Sabia D, Mompart S, Martín-Baranera M. Colorectal anastomosis during cytoreductive radical surgery in patients with peritoneal surface malignancies. Validation of a new technique (without stoma) to prevent anastomosis leakage in more than 1000 procedures. Clin Transl Oncol 2021;23:1201-9. [PMID: 33393053 DOI: 10.1007/s12094-020-02511-7] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
34 Huisman JF, van Westreenen HL, van der Wouden EJ, Vasen HFA, de Graaf EJR, Doornebosch PG, Tang TJ, Schot I, Brohet RM, de Vos Tot Nederveen Cappel WH, Vermaas M. Effectiveness of endosponge therapy for the management of presacral abscesses following rectal surgery. Tech Coloproctol 2019;23:551-7. [PMID: 31338710 DOI: 10.1007/s10151-019-02007-9] [Cited by in Crossref: 4] [Article Influence: 1.3] [Reference Citation Analysis]
35 Sparreboom CL, Wu Z, Lingsma HF, Menon AG, Kleinrensink G, Nuyttens JJ, Wouters MW, Lange JF. Anastomotic Leakage and Interval between Preoperative Short-Course Radiotherapy and Operation for Rectal Cancer. Journal of the American College of Surgeons 2018;227:223-31. [DOI: 10.1016/j.jamcollsurg.2018.03.034] [Cited by in Crossref: 6] [Cited by in F6Publishing: 6] [Article Influence: 1.5] [Reference Citation Analysis]
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37 Cho SH, Lee IK, Lee YS, Kim MK. The usefulness of transanal tube for reducing anastomotic leak in mid rectal cancer: compared to diverting stoma. Ann Surg Treat Res 2021;100:100-8. [PMID: 33585354 DOI: 10.4174/astr.2021.100.2.100] [Reference Citation Analysis]
38 Major P, Wysocki M, Pędziwiatr M, Pisarska M, Małczak P, Wierdak M, Dembiński M, Migaczewski M, Rubinkiewicz M, Budzyński A. More stapler firings increase the risk of perioperative morbidity after laparoscopic sleeve gastrectomy. Wideochir Inne Tech Maloinwazyjne 2018;13:88-94. [PMID: 29643964 DOI: 10.5114/wiitm.2017.70197] [Cited by in Crossref: 2] [Cited by in F6Publishing: 6] [Article Influence: 0.4] [Reference Citation Analysis]
39 Noh GT, Ann YS, Cheong C, Han J, Cho MS, Hur H, Min BS, Lee KY, Kim NK. Impact of anastomotic leakage on long-term oncologic outcome and its related factors in rectal cancer. Medicine (Baltimore). 2016;95:e4367. [PMID: 27472726 DOI: 10.1097/md.0000000000004367] [Cited by in Crossref: 18] [Cited by in F6Publishing: 8] [Article Influence: 3.6] [Reference Citation Analysis]
40 Wang P, Liang JW, Zhou HT, Wang Z, Zhou ZX. Surgical specimen extraction via a prophylactic ileostomy procedure: A minimally invasive technique for laparoscopic rectal cancer surgery. World J Gastroenterol 2018; 24(1): 104-111 [PMID: 29358887 DOI: 10.3748/wjg.v24.i1.104] [Cited by in CrossRef: 3] [Cited by in F6Publishing: 2] [Article Influence: 0.8] [Reference Citation Analysis]
41 Balciscueta Z, Uribe N, Caubet L, López M, Torrijo I, Tabet J, Martín MC. Impact of the number of stapler firings on anastomotic leakage in laparoscopic rectal surgery: a systematic review and meta-analysis. Tech Coloproctol 2020;24:919-25. [DOI: 10.1007/s10151-020-02240-7] [Cited by in Crossref: 4] [Cited by in F6Publishing: 3] [Article Influence: 2.0] [Reference Citation Analysis]
42 Ferko A, Váňa J, Adámik M, Švec A, Žáček M, Demeter M, Grendár M. Mucosa plication reinforced colorectal anastomosis and trans-anal vacuum drainage: a pilot study with preliminary results. Updates Surg 2021. [PMID: 34089500 DOI: 10.1007/s13304-021-01105-4] [Reference Citation Analysis]
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44 Xv Y, Fan J, Ding Y, Hu Y, Hu Y, Jiang Z, Tao Q. Latest Advances in Intersphincteric Resection for Low Rectal Cancer. Gastroenterol Res Pract 2020;2020:8928109. [PMID: 32765603 DOI: 10.1155/2020/8928109] [Reference Citation Analysis]
45 Pryn PS, Polovinkin VV. [Splenic flexure mobilization in surgery for rectal cancer]. Khirurgiia (Mosk) 2020;:94-9. [PMID: 31994507 DOI: 10.17116/hirurgia202001194] [Reference Citation Analysis]
46 Kim JC, Lee JL, Park SH. Interpretative Guidelines and Possible Indications for Indocyanine Green Fluorescence Imaging in Robot-Assisted Sphincter-Saving Operations. Dis Colon Rectum. 2017;60:376-384. [PMID: 28267004 DOI: 10.1097/dcr.0000000000000782] [Cited by in Crossref: 26] [Cited by in F6Publishing: 9] [Article Influence: 5.2] [Reference Citation Analysis]
47 Kuk JC, Lim DR, Shin EJ. Effect of transanal drainage tube of anastomotic leakage following low anterior resection without a defunctioning stoma for rectal cancer. Asian J Surg 2021:S1015-9584(21)00788-0. [PMID: 34953640 DOI: 10.1016/j.asjsur.2021.12.026] [Reference Citation Analysis]
48 Herzig DO, Ogilvie JW, Chudzinski A, Ferrara A, Ashraf SQ, Jimenez-Rodriguez RM, Van der Speeten K, Kinross J, Schimmelpenning H, Sagar PM, Cannon JA, Schwiers ML, Singleton DW, Waggoner JR, Fryrear R 2nd, Sylla P. Assessment of a circular powered stapler for creation of anastomosis in left-sided colorectal surgery: A prospective cohort study. Int J Surg 2020;84:140-6. [PMID: 33176211 DOI: 10.1016/j.ijsu.2020.11.001] [Cited by in Crossref: 4] [Cited by in F6Publishing: 5] [Article Influence: 2.0] [Reference Citation Analysis]
49 Wu Y, Zheng H, Guo T, Keranmu A, Liu F, Xu Y. Temporary Diverting Stoma Improves Recovery of Anastomotic Leakage after Anterior Resection for Rectal Cancer. Sci Rep 2017;7:15930. [PMID: 29162894 DOI: 10.1038/s41598-017-16311-7] [Cited by in Crossref: 4] [Cited by in F6Publishing: 3] [Article Influence: 0.8] [Reference Citation Analysis]
50 Chen Z, Yang J, Liu Z, Zhang Y, Sun J, Wang P. Which obesity-associated parameters can better reflect the risk of the occurrence of the anastomotic leakage? Scand J Gastroenterol 2020;55:466-71. [PMID: 32285713 DOI: 10.1080/00365521.2020.1748223] [Reference Citation Analysis]
51 Reif de Paula T, Simon H, Shah M, Lee-Kong S, Kiely JM, Kiran RP, Keller DS. Analysis of the impact of EEA stapler size on risk of anastomotic complications in colorectal anastomosis: does size matter? Tech Coloproctol 2020;24:283-90. [PMID: 32036461 DOI: 10.1007/s10151-020-02155-3] [Cited by in Crossref: 1] [Article Influence: 0.5] [Reference Citation Analysis]
52 Carboni F, Valle M, Levi Sandri GB, Giofrè M, Federici O, Zazza S, Garofalo A. Transanal drainage tube: alternative option to defunctioning stoma in rectal cancer surgery? Transl Gastroenterol Hepatol 2020;5:6. [PMID: 32190774 DOI: 10.21037/tgh.2019.10.16] [Cited by in Crossref: 4] [Cited by in F6Publishing: 1] [Article Influence: 2.0] [Reference Citation Analysis]
53 Kim JC, Yu CS, Lim SB, Park IJ, Kim CW, Yoon YS. Comparative analysis focusing on surgical and early oncological outcomes of open, laparoscopy-assisted, and robot-assisted approaches in rectal cancer patients. Int J Colorectal Dis. 2016;31:1179-1187. [PMID: 27080161 DOI: 10.1007/s00384-016-2586-6] [Cited by in Crossref: 20] [Cited by in F6Publishing: 17] [Article Influence: 3.3] [Reference Citation Analysis]
54 Chang YK, Foo CC, Yip J, Wei R, Ng KK, Lo O, Choi HK, Law WL. The impact of indocyanine-green fluorescence angiogram on colorectal resection. The Surgeon 2019;17:270-6. [DOI: 10.1016/j.surge.2018.08.006] [Cited by in Crossref: 16] [Cited by in F6Publishing: 15] [Article Influence: 5.3] [Reference Citation Analysis]
55 Liu XH, Wu XR, Zhou C, Zheng XB, Ke J, Liu HS, Hu T, Chen YF, He XW, He XS, Chen YL, Zou YF, Wang JP, Wu XJ, Lan P. Conversion is a risk factor for postoperative anastomotic leak in rectal cancer patients - A retrospective cohort study. Int J Surg. 2018;53:298-303. [PMID: 29367043 DOI: 10.1016/j.ijsu.2018.01.024] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 0.8] [Reference Citation Analysis]
56 Laporte GA, Zanini LAG, Zanvettor PH, Oliveira AF, Bernado E, Lissa F, Coelho MJP, Ribeiro R, Araujo RLC, Barrozo AJJ, da Costa AF, de Barros Júnior AP, Lopes A, Santos APM, Azevedo BRB, Sarmento BJQ, Marins CAM, Loureiro CMB, Galhardo CAV, Gatelli CN, Quadros CA, Pinto CV, Uchôa DNAO, Martins DRS, Doria-Filho E, Ribeiro EKMA, Pinto ERF, Dos Santos EAS, Gozi FAM, Nascimento FC, Fernandes FG, Gomes FKL, Nascimento GJS, Cucolicchio GO, Ritt GF, de Oliveira GG, Ayala GP, Guimarães GC, Ianaze GC, Gobetti GA, Medeiros GM, Güth GZ, Neto HFC, Figueiredo HF, Simões JC, Ferrari JC, Furtado JPR, Vieira LJ, Pereira LF, de Almeida LCF, Tayeh MRA, Figueiredo PHM, Pereira RSAV, Macedo RO, Sacramento RMM, Cardoso RM, Zanatto RM, Martinho RAM, Araújo RG, Pinheiro RN, Reis RJ, Goiânia SBS, Costa SRP, Foiato TF, Silva TC, Carneiro VCG, Oliveira VR, Casteleins WA. Guidelines of the Brazilian Society of Oncologic Surgery for pelvic exenteration in the treatment of cervical cancer. J Surg Oncol 2020;121:718-29. [PMID: 31777095 DOI: 10.1002/jso.25759] [Cited by in F6Publishing: 2] [Reference Citation Analysis]
57 Pla-Martí V, Martín-Arévalo J, Moro-Valdezate D, García-Botello S, Mora-Oliver I, Gadea-Mateo R, Cozar-Lozano C, Espí-Macías A. Impact of the novel powered circular stapler on risk of anastomotic leakage in colorectal anastomosis: a propensity score-matched study. Tech Coloproctol 2021;25:279-84. [PMID: 32914268 DOI: 10.1007/s10151-020-02338-y] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 1.5] [Reference Citation Analysis]
58 Wirth U, Rogers S, Haubensak K, Schopf S, von Ahnen T, Schardey HM. Local antibiotic decontamination to prevent anastomotic leakage short-term outcome in rectal cancer surgery. Int J Colorectal Dis 2018;33:53-60. [PMID: 29119289 DOI: 10.1007/s00384-017-2933-2] [Cited by in Crossref: 12] [Cited by in F6Publishing: 7] [Article Influence: 2.4] [Reference Citation Analysis]
59 Rosendorf J, Klicova M, Cervenkova L, Palek R, Horakova J, Klapstova A, Hosek P, Moulisova V, Bednar L, Tegl V, Brzon O, Tonar Z, Treska V, Lukas D, Liska V. Double-layered Nanofibrous Patch for Prevention of Anastomotic Leakage and Peritoneal Adhesions, Experimental Study. In Vivo 2021;35:731-41. [PMID: 33622866 DOI: 10.21873/invivo.12314] [Reference Citation Analysis]
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