Systematic Reviews
Copyright ©The Author(s) 2016.
World J Hepatol. Feb 8, 2016; 8(4): 231-262
Published online Feb 8, 2016. doi: 10.4254/wjh.v8.i4.231
Table 6 Therapies affecting the severity or the risk of bleeding from portal hypertensive gastropathy
Therapies reducing severity of PHGRef.
TIPS[76,77,98]
Transcatheter splenic arterial embolization[99]
Surgical shunt
Portocaval shunt[100]
Central splenorenal shunt[101]
Laparoscopic splenectomy (in patients with hypersplenism)[55]
Liver transplantation[44]
Therapies reducing risk of bleeding from PHG
TIPS[75,98,102]
Surgical shunt (portocaval or splenorenal)[100,101]
Nonselective b β-adrenergic receptor antagonists (e.g., propranolol)[103 (in rats),104]
Somatostatin family of drugs
Somatostatin[105]
Octreotide[106]
Vasopressin family of drugs
Vasopressin[106]
Terlipressin[107]
Therapies that increase incidence or risk of bleeding from PHG
Endoscopic therapies for varices
Variceal ligation[11,41]
Variceal sclerotherapy[11,83]
Interventional angiography
Percutaneous transhepatic variceal embolization[85]