Systematic Reviews
Copyright ©The Author(s) 2016.
World J Hepatol. Feb 8, 2016; 8(4): 231-262
Published online Feb 8, 2016. doi: 10.4254/wjh.v8.i4.231
Table 11 Rates of gastrointestinal bleeding from portal hypertensive gastropathy
Ref.Year publishedPopulationBleeding from PHGTransfusions required
McCormack et al[3]1985127 patients with portal hypertension of various etiologies29 patients out of 65 with PHG, representing 25% of the total number of bleeds from all sources; 9 episodes presenting with bleeding; 71 episodes of subsequent bleeding2-15 units required for 60 bleeds
D'Amico et al[25]1990212 patients with cirrhosis; 75 being treated with sclerotherapy
Sarin et al[8]1992107 patients with portal hypertension presenting with variceal bleeding, undergoing sclerotherapyNo bleeding before sclerotherapy from PHG (4/107 had PHG); 2/13 post-sclerotherapy patients who developed PHGAverage of 4 units per patient with range of 2-8 units
Pérez-Ayuso et al[103]199154 cirrhotic patients with PHG, in a RCT to look for rebleeding; propranolol 26 vs control 28First hemorrhage: Acute/chronic bleeding in propranolol group 12/14; in control 12/16, rebleeding: Acute/chronic; in propranolol 6/6; in control 10/12
Gostout et al[217]1993Patients admitted for GI bleeding (1496)12 patients (0.8%), representing 8% of nonvariceal bleeding in patients with liver disease
Primignani et al[34]2000373 patients with cirrhosis; PHG in 299 patients (80.1%)8 PHG patients with acute bleeding; chronic bleeding in 34 patients
Merli et al[37]2004222 cirrhotic patients with portal hypertension; 48 patients with PHG on enrollmentDuring follow up for 47 ± 28 (SD) mo, acute bleeding 9, chronic bleeding 7 from PHG
Kimura et al[218]2014297 patients with living donor liver transplantation; retrospective analysis2 patients bled from PHG within 3 mo after transplantation