Beneficial effects of losartan or telmisartan on the local hepatic renin-angiotensin system to counter obesity in an experimental model

Figure 4 Local gene expression of the ACE2/MASr axis in the liver: ACE2 (A) and rMAS (B). B-Actin was used as an endogenous control to normalize the expression of the selected genes. Data are the means ± SD, n = 5 for each group. Differences between the groups were tested with one-way ANOVA and post hoc test of Holm–Sidak (P < 0.05) compared to the C group (a), HF group (c) and HFL group (e). ACE2: Angiotensin-converting enzyme 2; rMAS: MAS receptor; C: Control group; HF: High-fat diet; HFL: HF diet treated with losartan; HFT: HF diet treated with telmisartan.