Copyright ©The Author(s) 2018.
World J Hepatol. Jan 27, 2018; 10(1): 142-154
Published online Jan 27, 2018. doi: 10.4254/wjh.v10.i1.142
Table 6 Levels of sIL-2R, ALT, and HBV DNA in the sera of patients with chronic HBV infection (mean ± SD)
StudyFibrosis stage used
NASH Clinical Research Network Scoring System DefinitionSeven stages:
Kleiner et al[53], 2005F0: No fibrosis
F1a: Mild zone 3 sinusoidal fibrosis
F1b: Moderated zone 3 sinusoidal fibrosis
F1c: Peri-portal sinusoidal fibrosis
F2: Zone 3 sinusoidal fibrosis and peri-portal sinusoidal fibrosis
F3: Bridging fibrosis
F4: Cirrhosis
Brunt et al[54], 1999Stage 1: Zone 3 perisinusoidal/pericellular fibrosis; focally or extensively present
Stage 2: Zone 3 perisinusoidal/pericellular fibrosis with focal or extensive periportal fibrosis
Stage 3: Zone 3 perisinusoidal/pericellular fibrosis and portal fibrosis with focal or extensive bridging fibrosis
Stage 4: Cirrhosis