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As the professor of Liver Cancer Institute, I have been working in the basic study on metastasis and recurrence of liver cancer. My research work focused on early diagnosis and prevention for recurrence and metastasis of hepatocellular carcinoma. As a principal investigator, I am in charge of “National Natural Science Foundation of China”, “Specialized Research Fund for the Doctoral Program of Higher Education” etc., regarding hepatocellular carcinoma in the fields of early diagnosis, molecular mechanism exploring of recurrence and metastasis, and translational medicine. I have published a total of 93 papers including 60 SCI papers. As the first author or corresponding author, I have published a total of 30 papers including 22 SCI papers with the total impact factor of 111 points in the journals including Hepatology, Cancer Res, Clin Cancer Res etc. In addition, I have applied 7 patents and 6 patent authorization has been obtained.