BPG is committed to discovery and dissemination of knowledge
Cited by in F6Publishing
For: Uetrecht J, Naisbitt DJ. Idiosyncratic adverse drug reactions: current concepts. Pharmacol Rev. 2013;65:779-808. [PMID: 23476052 DOI: 10.1124/pr.113.007450] [Cited by in Crossref: 191] [Cited by in F6Publishing: 150] [Article Influence: 23.9] [Reference Citation Analysis]
Number Citing Articles
1 Mosedale M, Watkins PB. Understanding Idiosyncratic Toxicity: Lessons Learned from Drug-Induced Liver Injury. J Med Chem 2020;63:6436-61. [PMID: 32037821 DOI: 10.1021/acs.jmedchem.9b01297] [Cited by in Crossref: 13] [Cited by in F6Publishing: 8] [Article Influence: 13.0] [Reference Citation Analysis]
2 Weiler DL. Zonisamide-Induced Angle Closure and Myopic Shift. Optometry and Vision Science 2015;92:e46-51. [DOI: 10.1097/opx.0000000000000475] [Cited by in Crossref: 14] [Cited by in F6Publishing: 3] [Article Influence: 2.3] [Reference Citation Analysis]
3 Naisbitt DJ, Nattrass RG, Ogese MO. In vitro diagnosis of delayed-type drug hypersensitivity: mechanistic aspects and unmet needs. Immunol Allergy Clin North Am 2014;34:691-705, x. [PMID: 25017686 DOI: 10.1016/j.iac.2014.04.009] [Cited by in Crossref: 14] [Cited by in F6Publishing: 13] [Article Influence: 2.3] [Reference Citation Analysis]
4 Nattrass R, Faulkner L, Vocanson M, Antoine DJ, Kipar A, Kenna G, Nicolas J, Park BK, Naisbitt DJ. Activation of Flucloxacillin-Specific CD8+ T-Cells With the Potential to Promote Hepatocyte Cytotoxicity in a Mouse Model. Toxicol Sci 2015;146:146-56. [DOI: 10.1093/toxsci/kfv077] [Cited by in Crossref: 19] [Cited by in F6Publishing: 17] [Article Influence: 3.2] [Reference Citation Analysis]
5 Raschi E, Parisotto M, Forcesi E, La Placa M, Marchesini G, De Ponti F, Poluzzi E. Adverse events with sodium-glucose co-transporter-2 inhibitors: A global analysis of international spontaneous reporting systems. Nutr Metab Cardiovasc Dis 2017;27:1098-107. [PMID: 29174026 DOI: 10.1016/j.numecd.2017.10.008] [Cited by in Crossref: 15] [Cited by in F6Publishing: 13] [Article Influence: 3.8] [Reference Citation Analysis]
6 Bolleddula J, Chowdhury SK. Carbon-carbon bond cleavage and formation reactions in drug metabolism and the role of metabolic enzymes. Drug Metab Rev 2015;47:534-57. [PMID: 26390887 DOI: 10.3109/03602532.2015.1086781] [Cited by in Crossref: 6] [Cited by in F6Publishing: 4] [Article Influence: 1.0] [Reference Citation Analysis]
7 Duran-figueroa N, Badillo-corona JA, Naisbitt DJ, Castrejon-flores JL. Towards the development of mechanism-based biomarkers to diagnose drug hypersensitivity. Toxicol Res 2015;4:777-95. [DOI: 10.1039/c4tx00238e] [Cited by in Crossref: 3] [Article Influence: 0.5] [Reference Citation Analysis]
8 Yuan Z, Yuan Z, Hasnat M, Zhang H, Liang P, Sun L, Jiang Z, Zhang L. A new perspective of triptolide-associated hepatotoxicity: the relevance of NF- κ B and NF- κ B-mediated cellular FLICE-inhibitory protein. Acta Pharm Sin B 2020;10:861-77. [PMID: 32528833 DOI: 10.1016/j.apsb.2020.02.009] [Cited by in Crossref: 5] [Cited by in F6Publishing: 3] [Article Influence: 5.0] [Reference Citation Analysis]
9 Mosedale M. Mouse Population-Based Approaches to Investigate Adverse Drug Reactions. Drug Metab Dispos 2018;46:1787-95. [DOI: 10.1124/dmd.118.082834] [Cited by in Crossref: 6] [Cited by in F6Publishing: 4] [Article Influence: 2.0] [Reference Citation Analysis]
10 Mosedale M, Watkins PB. Drug-induced liver injury: Advances in mechanistic understanding that will inform risk management. Clin Pharmacol Ther 2017;101:469-80. [PMID: 27861792 DOI: 10.1002/cpt.564] [Cited by in Crossref: 91] [Cited by in F6Publishing: 76] [Article Influence: 22.8] [Reference Citation Analysis]
11 Simper GS, Hò GT, Celik AA, Huyton T, Kuhn J, Kunze-Schumacher H, Blasczyk R, Bade-Döding C. Carbamazepine-Mediated Adverse Drug Reactions: CBZ-10,11-epoxide but Not Carbamazepine Induces the Alteration of Peptides Presented by HLA-B∗15:02. J Immunol Res 2018;2018:5086503. [PMID: 30302345 DOI: 10.1155/2018/5086503] [Cited by in Crossref: 5] [Cited by in F6Publishing: 7] [Article Influence: 1.7] [Reference Citation Analysis]
12 Rao T, Liu YT, Zeng XC, Li CP, Ou-Yang DS. The hepatotoxicity of Polygonum multiflorum: The emerging role of the immune-mediated liver injury. Acta Pharmacol Sin. 2021;42:27-35. [PMID: 32123300 DOI: 10.1038/s41401-020-0360-3] [Cited by in Crossref: 5] [Cited by in F6Publishing: 8] [Article Influence: 5.0] [Reference Citation Analysis]
13 Holman NS, Mosedale M, Wolf KK, LeCluyse EL, Watkins PB. Subtoxic Alterations in Hepatocyte-Derived Exosomes: An Early Step in Drug-Induced Liver Injury? Toxicol Sci. 2016;151:365-375. [PMID: 26962055 DOI: 10.1093/toxsci/kfw047] [Cited by in Crossref: 50] [Cited by in F6Publishing: 44] [Article Influence: 10.0] [Reference Citation Analysis]
14 Matas S, Broto M, Corominas M, Lleonart R, Babington R, Marco M, Galve R. Immediate hypersensitivity to penicillins. Identification of a new antigenic determinant. Journal of Pharmaceutical and Biomedical Analysis 2018;148:17-23. [DOI: 10.1016/j.jpba.2017.08.024] [Cited by in Crossref: 4] [Cited by in F6Publishing: 3] [Article Influence: 1.3] [Reference Citation Analysis]
15 Ong TL, Dal S, Martin AJ, Chang FC, Williams LJ, Babu S, Mahant N, Morales-Briceno H, Fletcher N, Nankervis J, Robbie M, Fung VSC. Levodopa/dopa decarboxylase inhibitor associated microscopic colitis: An under-recognized drug reaction. Parkinsonism Relat Disord 2021;86:84-90. [PMID: 33894560 DOI: 10.1016/j.parkreldis.2021.03.031] [Cited by in F6Publishing: 1] [Reference Citation Analysis]
16 Metushi IG, Zhu X, Uetrecht J. D-penicillamine-induced granulomatous hepatitis in brown Norway rats. Mol Cell Biochem 2014;393:229-35. [DOI: 10.1007/s11010-014-2065-8] [Cited by in Crossref: 4] [Cited by in F6Publishing: 2] [Article Influence: 0.6] [Reference Citation Analysis]
17 Vickers AE, Ulyanov AV, Fisher RL. Liver Effects of Clinical Drugs Differentiated in Human Liver Slices. Int J Mol Sci 2017;18:E574. [PMID: 28272341 DOI: 10.3390/ijms18030574] [Cited by in Crossref: 6] [Cited by in F6Publishing: 5] [Article Influence: 1.5] [Reference Citation Analysis]
18 Inoue K, Mizuo H, Ishida T, Komori T, Kusano K. Bioactivation of diclofenac in human hepatocytes and the proposed human hepatic proteins modified by reactive metabolites. Xenobiotica 2020;50:919-28. [PMID: 32039641 DOI: 10.1080/00498254.2020.1728592] [Cited by in Crossref: 1] [Article Influence: 1.0] [Reference Citation Analysis]
19 Mizuno K, Takeuchi K, Umehara K, Nakajima M. Identification of Novel Metabolites of Vildagliptin in Rats: Thiazoline-Containing Thiol Adducts Formed via Cysteine or Glutathione Conjugation. Drug Metab Dispos 2019;47:809-17. [PMID: 31097424 DOI: 10.1124/dmd.119.086546] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
20 Leeming MG, Donald WA, O'Hair RAJ. Nontargeted Identification of Reactive Metabolite Protein Adducts. Anal Chem 2017;89:5748-56. [PMID: 28481086 DOI: 10.1021/acs.analchem.6b04604] [Cited by in Crossref: 11] [Cited by in F6Publishing: 9] [Article Influence: 2.8] [Reference Citation Analysis]
21 Dang NL, Matlock MK, Hughes TB, Swamidass SJ. The Metabolic Rainbow: Deep Learning Phase I Metabolism in Five Colors. J Chem Inf Model 2020;60:1146-64. [DOI: 10.1021/acs.jcim.9b00836] [Cited by in Crossref: 9] [Cited by in F6Publishing: 9] [Article Influence: 9.0] [Reference Citation Analysis]
22 Chong LH, Ng C, Li H, Tian EF, Ananthanarayanan A, McMillian M, Toh YC. Hepatic Bioactivation of Skin-Sensitizing Drugs to Immunogenic Reactive Metabolites. ACS Omega 2019;4:13902-12. [PMID: 31497708 DOI: 10.1021/acsomega.9b01551] [Reference Citation Analysis]
23 Boerma JS, Elias NS, Vermeulen NP, Commandeur JN. Mini-dialysis tubes as tools to prepare drug-protein adducts of P450-dependent reactive drug metabolites. Journal of Pharmaceutical and Biomedical Analysis 2015;103:17-25. [DOI: 10.1016/j.jpba.2014.10.025] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.2] [Reference Citation Analysis]
24 Annunziata G, Mayuko I, Barbara M. Idiosyncratic Liver Injury Due to Levocetirizine. ACG Case Rep J 2019;6:e00191. [PMID: 31737721 DOI: 10.14309/crj.0000000000000191] [Reference Citation Analysis]
25 McGill MR, Jaeschke H. Animal models of drug-induced liver injury. Biochim Biophys Acta Mol Basis Dis 2019;1865:1031-9. [PMID: 31007174 DOI: 10.1016/j.bbadis.2018.08.037] [Cited by in Crossref: 34] [Cited by in F6Publishing: 32] [Article Influence: 11.3] [Reference Citation Analysis]
26 Elzagallaai AA, Rieder MJ. In vitro testing for diagnosis of idiosyncratic adverse drug reactions: Implications for pathophysiology. Br J Clin Pharmacol 2015;80:889-900. [PMID: 25199801 DOI: 10.1111/bcp.12505] [Cited by in Crossref: 11] [Cited by in F6Publishing: 10] [Article Influence: 1.8] [Reference Citation Analysis]
27 Goldring C, Norris A, Kitteringham N, Aleo MD, Antoine DJ, Heslop J, Howell BA, Ingelman-sundberg M, Kia R, Kamalian L, Koerber S, Martinou J, Mercer A, Moggs J, Naisbitt DJ, Powell C, Sidaway J, Sison-young R, Snoeys J, van de Water B, Watkins PB, Weaver RJ, Wolf A, Zhang F, Park BK. Mechanism-Based Markers of Drug-Induced Liver Injury to Improve the Physiological Relevance and Predictivity of In Vitro Models. Applied In Vitro Toxicology 2015;1:175-86. [DOI: 10.1089/aivt.2015.0001] [Cited by in Crossref: 4] [Cited by in F6Publishing: 3] [Article Influence: 0.7] [Reference Citation Analysis]
28 Arantes LB, Reis CS, Novaes AG, Carvalho MR, Göttems LBD, Novaes MRCG. Stevens-Johnson syndrome and toxic epidermal necrolysis: epidemiological and clinical outcomes analysis in public hospitals. An Bras Dermatol 2017;92:661-7. [PMID: 29166503 DOI: 10.1590/abd1806-4841.20176610] [Cited by in Crossref: 10] [Cited by in F6Publishing: 8] [Article Influence: 3.3] [Reference Citation Analysis]
29 Garcia-Serna R, Vidal D, Remez N, Mestres J. Large-Scale Predictive Drug Safety: From Structural Alerts to Biological Mechanisms. Chem Res Toxicol 2015;28:1875-87. [PMID: 26360911 DOI: 10.1021/acs.chemrestox.5b00260] [Cited by in Crossref: 31] [Cited by in F6Publishing: 23] [Article Influence: 5.2] [Reference Citation Analysis]
30 Mizuno K, Takeuchi K, Umehara K, Nakajima M. Identification of a novel metabolite of vildagliptin in humans: Cysteine targets the nitrile moiety to form a thiazoline ring. Biochem Pharmacol 2018;156:312-21. [PMID: 30172711 DOI: 10.1016/j.bcp.2018.08.043] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 1.0] [Reference Citation Analysis]
31 Usui T, Meng X, Saide K, Farrell J, Thomson P, Whitaker P, Watson J, French NS, Kevin Park B, Naisbitt DJ. From the Cover: Characterization of Isoniazid-Specific T-Cell Clones in Patients with anti-Tuberculosis Drug-Related Liver and Skin Injury. Toxicol Sci 2017;155:420-31. [DOI: 10.1093/toxsci/kfw218] [Cited by in Crossref: 23] [Cited by in F6Publishing: 20] [Article Influence: 4.6] [Reference Citation Analysis]
32 Teschke R, Uetrecht J. Mechanism of idiosyncratic drug induced liver injury (DILI): unresolved basic issues. Ann Transl Med 2021;9:730. [PMID: 33987428 DOI: 10.21037/atm-2020-ubih-05] [Cited by in Crossref: 1] [Cited by in F6Publishing: 2] [Article Influence: 1.0] [Reference Citation Analysis]
33 Lee SJ, Lee YJ, Park KK. The pathogenesis of drug-induced liver injury. Expert Rev Gastroenterol Hepatol 2016;10:1175-85. [PMID: 27248313 DOI: 10.1080/17474124.2016.1196133] [Cited by in Crossref: 11] [Cited by in F6Publishing: 10] [Article Influence: 2.2] [Reference Citation Analysis]
34 Ma Q, Yang W, Wang L, Ma L, Jing Y, Wang J, Liu X. Research advances in the association of drug-induced liver injury with polymorphisms in human leukocyte antigen. Int Immunopharmacol 2020;81:106037. [PMID: 31784402 DOI: 10.1016/j.intimp.2019.106037] [Reference Citation Analysis]
35 Ye H, Nelson LJ, Gómez del Moral M, Martínez-Naves E, Cubero FJ. Dissecting the molecular pathophysiology of drug-induced liver injury. World J Gastroenterol 2018; 24(13): 1373-1385 [PMID: 29632419 DOI: 10.3748/wjg.v24.i13.1373] [Cited by in CrossRef: 31] [Cited by in F6Publishing: 26] [Article Influence: 10.3] [Reference Citation Analysis]
36 Sharma AM, Uetrecht J. Bioactivation of drugs in the skin: relationship to cutaneous adverse drug reactions. Drug Metabolism Reviews 2013;46:1-18. [DOI: 10.3109/03602532.2013.848214] [Cited by in Crossref: 19] [Cited by in F6Publishing: 15] [Article Influence: 2.4] [Reference Citation Analysis]
37 Wu H, Whritenour J, Sanford JC, Houle C, Adkins KK. Identification of MHC Haplotypes Associated with Drug-induced Hypersensitivity Reactions in Cynomolgus Monkeys. Toxicol Pathol 2017;45:127-33. [PMID: 27879435 DOI: 10.1177/0192623316677326] [Cited by in Crossref: 3] [Cited by in F6Publishing: 2] [Article Influence: 0.6] [Reference Citation Analysis]
38 Jee A, Sernoskie SC, Uetrecht J. Idiosyncratic Drug-Induced Liver Injury: Mechanistic and Clinical Challenges. Int J Mol Sci 2021;22:2954. [PMID: 33799477 DOI: 10.3390/ijms22062954] [Cited by in Crossref: 2] [Cited by in F6Publishing: 3] [Article Influence: 2.0] [Reference Citation Analysis]
39 Hughes TB, Dang NL, Kumar A, Flynn NR, Swamidass SJ. Metabolic Forest: Predicting the Diverse Structures of Drug Metabolites. J Chem Inf Model 2020;60:4702-16. [DOI: 10.1021/acs.jcim.0c00360] [Cited by in Crossref: 4] [Cited by in F6Publishing: 4] [Article Influence: 4.0] [Reference Citation Analysis]
40 Suzuki A, Yuen NA, Ilic K, Miller RT, Reese MJ, Brown HR, Ambroso JI, Falls JG, Hunt CM. Comedications alter drug-induced liver injury reporting frequency: Data mining in the WHO VigiBase™. Regul Toxicol Pharmacol 2015;72:481-90. [PMID: 25988394 DOI: 10.1016/j.yrtph.2015.05.004] [Cited by in Crossref: 23] [Cited by in F6Publishing: 18] [Article Influence: 3.8] [Reference Citation Analysis]
41 Manoj KM, Parashar A, Venkatachalam A, Goyal S, Satyalipsu, Singh PG, Gade SK, Periyasami K, Jacob RS, Sardar D, Singh S, Kumar R, Gideon DA. Atypical profiles and modulations of heme-enzymes catalyzed outcomes by low amounts of diverse additives suggest diffusible radicals' obligatory involvement in such redox reactions. Biochimie 2016;125:91-111. [DOI: 10.1016/j.biochi.2016.03.003] [Cited by in Crossref: 21] [Cited by in F6Publishing: 18] [Article Influence: 4.2] [Reference Citation Analysis]
42 Masuka JT, Muzopambwa G, Khoza S, Chibanda D. An Interesting Case of Carbamazepine-Induced Stevens-Johnson Syndrome. Drug Saf Case Rep 2018;6:1. [PMID: 30535610 DOI: 10.1007/s40800-018-0095-y] [Cited by in Crossref: 3] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
43 Palanisamy GS, Marcek JM, Cappon GD, Whritenour J, Shaffer CL, Brady JT, Houle C. Drug-induced Skin Lesions in Cynomolgus Macaques Treated with Metabotropic Glutamate Receptor 5 (mGluR5) Negative Allosteric Modulators. Toxicol Pathol 2015;43:995-1003. [DOI: 10.1177/0192623315588114] [Cited by in Crossref: 9] [Cited by in F6Publishing: 6] [Article Influence: 1.5] [Reference Citation Analysis]
44 Bianco G, Goodsell DS, Forli S. Selective and Effective: Current Progress in Computational Structure-Based Drug Discovery of Targeted Covalent Inhibitors. Trends Pharmacol Sci 2020;41:1038-49. [PMID: 33153778 DOI: 10.1016/j.tips.2020.10.005] [Cited by in Crossref: 3] [Cited by in F6Publishing: 2] [Article Influence: 3.0] [Reference Citation Analysis]
45 Amacher DE. Female gender as a susceptibility factor for drug-induced liver injury. Hum Exp Toxicol. 2014;33:928-939. [PMID: 24299907 DOI: 10.1177/0960327113512860] [Cited by in Crossref: 39] [Cited by in F6Publishing: 31] [Article Influence: 4.9] [Reference Citation Analysis]
46 Lewis JH. The Art and Science of Diagnosing and Managing Drug-induced Liver Injury in 2015 and Beyond. Clin Gastroenterol Hepatol. 2015;13:2173-2189.e8. [PMID: 26116527 DOI: 10.1016/j.cgh.2015.06.017] [Cited by in Crossref: 47] [Cited by in F6Publishing: 39] [Article Influence: 7.8] [Reference Citation Analysis]
47 Iasella CJ, Johnson HJ, Dunn MA. Adverse Drug Reactions: Type A (Intrinsic) or Type B (Idiosyncratic). Clin Liver Dis 2017;21:73-87. [PMID: 27842776 DOI: 10.1016/j.cld.2016.08.005] [Cited by in Crossref: 25] [Cited by in F6Publishing: 17] [Article Influence: 5.0] [Reference Citation Analysis]
48 Chaikuad A, Koch P, Laufer SA, Knapp S. The Cysteinome of Protein Kinases as a Target in Drug Development. Angew Chem Int Ed 2018;57:4372-85. [DOI: 10.1002/anie.201707875] [Cited by in Crossref: 98] [Cited by in F6Publishing: 73] [Article Influence: 32.7] [Reference Citation Analysis]
49 Hunt CM, Papay JI, Stanulovic V, Regev A. Drug rechallenge following drug-induced liver injury. Hepatology 2017;66:646-54. [PMID: 28295448 DOI: 10.1002/hep.29152] [Cited by in Crossref: 28] [Cited by in F6Publishing: 28] [Article Influence: 7.0] [Reference Citation Analysis]
50 Zhao Q, Alhilali K, Alzahrani A, Almutairi M, Amjad J, Liu H, Sun Y, Sun L, Zhang H, Meng X, Gibson A, Ogese MO, Kevin Park B, Liu J, Ostrov DA, Zhang F, Naisbitt DJ. Dapsone- and nitroso dapsone-specific activation of T cells from hypersensitive patients expressing the risk allele HLA-B*13:01. Allergy 2019;74:1533-48. [PMID: 30844087 DOI: 10.1111/all.13769] [Cited by in Crossref: 10] [Cited by in F6Publishing: 14] [Article Influence: 5.0] [Reference Citation Analysis]
51 McGill MR, Jaeschke H. MicroRNAs as Signaling Mediators and Biomarkers of Drug- and Chemical-Induced Liver Injury. J Clin Med. 2015;4:1063-1078. [PMID: 26167291 DOI: 10.3390/jcm4051063] [Cited by in Crossref: 29] [Cited by in F6Publishing: 28] [Article Influence: 4.8] [Reference Citation Analysis]
52 Micaglio E, Locati ET, Monasky MM, Romani F, Heilbron F, Pappone C. Role of Pharmacogenetics in Adverse Drug Reactions: An Update towards Personalized Medicine. Front Pharmacol 2021;12:651720. [PMID: 33995067 DOI: 10.3389/fphar.2021.651720] [Reference Citation Analysis]
53 Yang F, Xuan J, Chen J, Zhong H, Luo H, Zhou P, Sun X, He L, Chen S, Cao Z, Luo X, Xing Q. HLA-B*59:01: a marker for Stevens-Johnson syndrome/toxic epidermal necrolysis caused by methazolamide in Han Chinese. Pharmacogenomics J 2016;16:83-7. [PMID: 25918017 DOI: 10.1038/tpj.2015.25] [Cited by in Crossref: 32] [Cited by in F6Publishing: 24] [Article Influence: 5.3] [Reference Citation Analysis]
54 Huang H, Bai X, Yang L. Theoretical study on the mechanism of N- and α-carbon oxidation of lapatinib catalyzed by cytochrome P450 monooxygenase. J Mol Model 2019;25:225. [PMID: 31312984 DOI: 10.1007/s00894-019-4125-1] [Cited by in Crossref: 1] [Article Influence: 0.5] [Reference Citation Analysis]
55 Roth AD, Lee MY. Idiosyncratic Drug-Induced Liver Injury (IDILI): Potential Mechanisms and Predictive Assays. Biomed Res Int 2017;2017:9176937. [PMID: 28133614 DOI: 10.1155/2017/9176937] [Cited by in Crossref: 15] [Cited by in F6Publishing: 17] [Article Influence: 3.8] [Reference Citation Analysis]
56 Vivas LLY, Gold WL, Mandell DM, Wu PE. An 82-year-old man with ataxia and dysarthria. CMAJ 2016;188:1251-4. [PMID: 26464138 DOI: 10.1503/cmaj.150573] [Cited by in Crossref: 3] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
57 Rattay B, Benndorf RA. Drug-Induced Idiosyncratic Agranulocytosis - Infrequent but Dangerous. Front Pharmacol 2021;12:727717. [PMID: 34483939 DOI: 10.3389/fphar.2021.727717] [Reference Citation Analysis]
58 Balakirski G, Merk HF. Cutaneous allergic drug reactions: update on pathophysiology, diagnostic procedures and differential diagnosic. Cutaneous and Ocular Toxicology 2017;36:307-16. [DOI: 10.1080/15569527.2017.1319379] [Cited by in Crossref: 6] [Cited by in F6Publishing: 3] [Article Influence: 1.5] [Reference Citation Analysis]
59 Lewis JH. Drug-induced liver injury, dosage, and drug disposition: is idiosyncrasy really unpredictable? Clin Gastroenterol Hepatol. 2014;12:1556-1561. [PMID: 24530601 DOI: 10.1016/j.cgh.2014.02.011] [Cited by in Crossref: 5] [Cited by in F6Publishing: 6] [Article Influence: 0.7] [Reference Citation Analysis]
60 Wheatley LM, Plaut M, Schwaninger JM, Banerji A, Castells M, Finkelman FD, Gleich GJ, Guttman-Yassky E, Mallal SA, Naisbitt DJ, Ostrov DA, Phillips EJ, Pichler WJ, Platts-Mills TA, Roujeau JC, Schwartz LB, Trepanier LA. Report from the National Institute of Allergy and Infectious Diseases workshop on drug allergy. J Allergy Clin Immunol 2015;136:262-71.e2. [PMID: 26254053 DOI: 10.1016/j.jaci.2015.05.027] [Cited by in Crossref: 35] [Cited by in F6Publishing: 32] [Article Influence: 5.8] [Reference Citation Analysis]
61 Tailor A, Waddington JC, Meng X, Park BK. Mass Spectrometric and Functional Aspects of Drug–Protein Conjugation. Chem Res Toxicol 2016;29:1912-35. [DOI: 10.1021/acs.chemrestox.6b00147] [Cited by in Crossref: 25] [Cited by in F6Publishing: 20] [Article Influence: 5.0] [Reference Citation Analysis]
62 Sabbioni G, Turesky RJ. Biomonitoring Human Albumin Adducts: The Past, the Present, and the Future. Chem Res Toxicol 2017;30:332-66. [PMID: 27989119 DOI: 10.1021/acs.chemrestox.6b00366] [Cited by in Crossref: 58] [Cited by in F6Publishing: 48] [Article Influence: 11.6] [Reference Citation Analysis]
63 Curtis BR. Non-chemotherapy drug-induced neutropenia: key points to manage the challenges. Hematology Am Soc Hematol Educ Program 2017;2017:187-93. [PMID: 29222255 DOI: 10.1182/asheducation-2017.1.187] [Cited by in Crossref: 17] [Cited by in F6Publishing: 14] [Article Influence: 5.7] [Reference Citation Analysis]
64 Autrel-Moignet A, Lamy T. Autoimmune neutropenia. Presse Med 2014;43:e105-18. [PMID: 24680423 DOI: 10.1016/j.lpm.2014.02.007] [Cited by in Crossref: 11] [Cited by in F6Publishing: 8] [Article Influence: 1.6] [Reference Citation Analysis]
65 Saavedra PA, Meiners MM, Lopes LC, Silva EV, Silva DL, Noronha EF, Toledo MI. Adverse drug reactions among patients admitted with infectious diseases at a Brazilian hospital. Rev Soc Bras Med Trop 2016;49:763-7. [PMID: 28001225 DOI: 10.1590/0037-8682-0238-2016] [Cited by in Crossref: 2] [Cited by in F6Publishing: 1] [Article Influence: 0.5] [Reference Citation Analysis]
66 Ocete-Hita E, Salmerón-Fernández M, Urrutia-Maldonado E, Muñoz-de-Rueda P, Salmerón-Ruiz M, Martinez-Padilla M, Ruiz-Extremera A. Analysis of Immunogenetic Factors in Idiosyncratic Drug-induced Liver Injury in the Pediatric Population. J Pediatr Gastroenterol Nutr 2017;64:742-7. [PMID: 28005582 DOI: 10.1097/MPG.0000000000001502] [Cited by in Crossref: 7] [Cited by in F6Publishing: 3] [Article Influence: 2.3] [Reference Citation Analysis]
67 Hirasawa M, Hagihara K, Abe K, Ando O, Hirayama N. In Silico and In Vitro Analysis of Interaction between Ximelagatran and Human Leukocyte Antigen (HLA)-DRB1*07:01. Int J Mol Sci 2017;18:E694. [PMID: 28338626 DOI: 10.3390/ijms18040694] [Cited by in Crossref: 9] [Cited by in F6Publishing: 8] [Article Influence: 2.3] [Reference Citation Analysis]
68 Zhou Y, Krebs K, Milani L, Lauschke VM. Global Frequencies of Clinically Important HLA Alleles and Their Implications For the Cost-Effectiveness of Preemptive Pharmacogenetic Testing. Clin Pharmacol Ther 2021;109:160-74. [PMID: 32535895 DOI: 10.1002/cpt.1944] [Cited by in Crossref: 9] [Cited by in F6Publishing: 10] [Article Influence: 9.0] [Reference Citation Analysis]
69 Kadia BM, Morfaw C, Simo ACG. Choreoathetosis - an unusual adverse effect of dihydroartemisinin-piperaquine: a case report. J Med Case Rep 2017;11:360. [PMID: 29282155 DOI: 10.1186/s13256-017-1525-7] [Cited by in Crossref: 2] [Article Influence: 0.5] [Reference Citation Analysis]
70 Monti-Rocha R, Cramer A, Gaio Leite P, Antunes MM, Pereira RVS, Barroso A, Queiroz-Junior CM, David BA, Teixeira MM, Menezes GB, Machado FS. SOCS2 Is Critical for the Balancing of Immune Response and Oxidate Stress Protecting Against Acetaminophen-Induced Acute Liver Injury. Front Immunol 2018;9:3134. [PMID: 30723477 DOI: 10.3389/fimmu.2018.03134] [Cited by in Crossref: 10] [Cited by in F6Publishing: 10] [Article Influence: 5.0] [Reference Citation Analysis]
71 Kenna JG, Thompson RA. INTEGRATED REACTIVE METABOLITE STRATEGIES. In: Iverson SL, Smith DA, editors. Metabolite Safety in Drug Development. Hoboken: John Wiley & Sons, Inc.; 2016. pp. 111-39. [DOI: 10.1002/9781118949689.ch5] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.2] [Reference Citation Analysis]
72 Ayuso P, García-Martín E, Agúndez JAG. Variability of the Genes Involved in the Cellular Redox Status and Their Implication in Drug Hypersensitivity Reactions. Antioxidants (Basel) 2021;10:294. [PMID: 33672092 DOI: 10.3390/antiox10020294] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
73 Gan J, Zhang H, Humphreys WG. Drug–Protein Adducts: Chemistry, Mechanisms of Toxicity, and Methods of Characterization. Chem Res Toxicol 2016;29:2040-57. [DOI: 10.1021/acs.chemrestox.6b00274] [Cited by in Crossref: 23] [Cited by in F6Publishing: 16] [Article Influence: 4.6] [Reference Citation Analysis]
74 Sernoskie SC, Jee A, Uetrecht JP. The Emerging Role of the Innate Immune Response in Idiosyncratic Drug Reactions. Pharmacol Rev 2021;73:861-96. [PMID: 34016669 DOI: 10.1124/pharmrev.120.000090] [Reference Citation Analysis]
75 Nicoletti P, Barrett S, McEvoy L, Daly AK, Aithal G, Lucena MI, Andrade RJ, Wadelius M, Hallberg P, Stephens C, Bjornsson ES, Friedmann P, Kainu K, Laitinen T, Marson A, Molokhia M, Phillips E, Pichler W, Romano A, Shear N, Sills G, Tanno LK, Swale A, Floratos A, Shen Y, Nelson MR, Watkins PB, Daly MJ, Morris AP, Alfirevic A, Pirmohamed M. Shared Genetic Risk Factors Across Carbamazepine-Induced Hypersensitivity Reactions. Clin Pharmacol Ther 2019;106:1028-36. [PMID: 31066027 DOI: 10.1002/cpt.1493] [Cited by in Crossref: 26] [Cited by in F6Publishing: 15] [Article Influence: 13.0] [Reference Citation Analysis]
76 Susukida T, Kuwahara S, Song B, Kazaoka A, Aoki S, Ito K. Regulation of the immune tolerance system determines the susceptibility to HLA-mediated abacavir-induced skin toxicity. Commun Biol 2021;4:1137. [PMID: 34584206 DOI: 10.1038/s42003-021-02657-2] [Reference Citation Analysis]
77 Donnez J, Arriagada P, Marciniak M, Larrey D. Liver safety parameters of ulipristal acetate for the treatment of uterine fibroids: a comprehensive review of the clinical development program. Expert Opin Drug Saf 2018;17:1225-32. [PMID: 30460871 DOI: 10.1080/14740338.2018.1550070] [Cited by in Crossref: 34] [Cited by in F6Publishing: 30] [Article Influence: 11.3] [Reference Citation Analysis]
78 Mosedale M, Cai Y, Eaddy JS, Corty RW, Nautiyal M, Watkins PB, Valdar W. Identification of Candidate Risk Factor Genes for Human Idelalisib Toxicity Using a Collaborative Cross Approach. Toxicol Sci 2019;172:265-78. [PMID: 31501888 DOI: 10.1093/toxsci/kfz199] [Cited by in Crossref: 12] [Cited by in F6Publishing: 9] [Article Influence: 12.0] [Reference Citation Analysis]
79 Liu F, Jiao AX, Wu XR, Zhao W, Yin QQ, Qi H, Jiao WW, Xiao J, Sun L, Shen C, Tian JL, Shen D, Jacqz-Aigrain E, Shen AD. Impact of glutathione S-transferase M1 and T1 on anti-tuberculosis drug-induced hepatotoxicity in Chinese pediatric patients. PLoS One 2014;9:e115410. [PMID: 25525805 DOI: 10.1371/journal.pone.0115410] [Cited by in Crossref: 10] [Cited by in F6Publishing: 12] [Article Influence: 1.4] [Reference Citation Analysis]
80 Bascones-Martínez A, García-García V, Meurman JH, Requena-Caballero L. Immune-mediated diseases: what can be found in the oral cavity? Int J Dermatol 2015;54:258-70. [PMID: 25514833 DOI: 10.1111/ijd.12681] [Cited by in Crossref: 14] [Cited by in F6Publishing: 10] [Article Influence: 2.0] [Reference Citation Analysis]
81 Yang Z, He J, Lu A, Hou T, Cao D. Application of Negative Design To Design a More Desirable Virtual Screening Library. J Med Chem 2020;63:4411-29. [DOI: 10.1021/acs.jmedchem.9b01476] [Cited by in Crossref: 11] [Cited by in F6Publishing: 8] [Article Influence: 11.0] [Reference Citation Analysis]
82 Ganapathineedi B, Mehta A, Dande S, Shinde A, Barsky G, Sebro N. Bullous Pemphigoid with Atypical Skin Lesions and Acute Interstitial Nephritis: A Case Report and Focused Literature Review. Am J Case Rep 2019;20:212-8. [PMID: 30773528 DOI: 10.12659/AJCR.911422] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 1.5] [Reference Citation Analysis]
83 Baillie TA. Targeted Covalent Inhibitors for Drug Design. Angew Chem Int Ed 2016;55:13408-21. [DOI: 10.1002/anie.201601091] [Cited by in Crossref: 248] [Cited by in F6Publishing: 211] [Article Influence: 49.6] [Reference Citation Analysis]
84 Khalil A, Parker M, Brown SE, Cevik SE, Guo LW, Jensen J, Olmsted A, Portman D, Wu H, Suvorov A. Perinatal exposure to 2,2',4'4' -Tetrabromodiphenyl ether induces testicular toxicity in adult rats. Toxicology 2017;389:21-30. [PMID: 28712647 DOI: 10.1016/j.tox.2017.07.006] [Cited by in Crossref: 22] [Cited by in F6Publishing: 22] [Article Influence: 5.5] [Reference Citation Analysis]
85 Yoon EL, Yuk J. Use of Ulipristal Acetate and Risk of Liver Disease: A Nationwide Cohort Study. The Journal of Clinical Endocrinology & Metabolism 2021;106:1773-82. [DOI: 10.1210/clinem/dgab081] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
86 Walkey C, Das S, Seal S, Erlichman J, Heckman K, Ghibelli L, Traversa E, McGinnis JF, Self WT. Catalytic Properties and Biomedical Applications of Cerium Oxide Nanoparticles. Environ Sci Nano 2015;2:33-53. [PMID: 26207185 DOI: 10.1039/C4EN00138A] [Cited by in Crossref: 183] [Cited by in F6Publishing: 59] [Article Influence: 30.5] [Reference Citation Analysis]
87 Puig M, Ananthula S, Venna R, Kumar Polumuri S, Mattson E, Walker LM, Cardone M, Takahashi M, Su S, Boyd LF, Natarajan K, Abdoulaeva G, Wu WW, Roderiquez G, Hildebrand WH, Beaucage SL, Li Z, Margulies DH, Norcross MA. Alterations in the HLA-B*57:01 Immunopeptidome by Flucloxacillin and Immunogenicity of Drug-Haptenated Peptides. Front Immunol 2020;11:629399. [PMID: 33633747 DOI: 10.3389/fimmu.2020.629399] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 2.0] [Reference Citation Analysis]
88 Thompson RA, Isin EM, Ogese MO, Mettetal JT, Williams DP. Reactive Metabolites: Current and Emerging Risk and Hazard Assessments. Chem Res Toxicol 2016;29:505-33. [DOI: 10.1021/acs.chemrestox.5b00410] [Cited by in Crossref: 79] [Cited by in F6Publishing: 64] [Article Influence: 15.8] [Reference Citation Analysis]
89 McConnell H, Andrews TD, Field MA. Efficacy of computational predictions of the functional effect of idiosyncratic pharmacogenetic variants. PeerJ 2021;9:e11774. [PMID: 34316407 DOI: 10.7717/peerj.11774] [Reference Citation Analysis]
90 Scarpino A, Ferenczy GG, Keserű GM. Comparative Evaluation of Covalent Docking Tools. J Chem Inf Model 2018;58:1441-58. [DOI: 10.1021/acs.jcim.8b00228] [Cited by in Crossref: 47] [Cited by in F6Publishing: 44] [Article Influence: 15.7] [Reference Citation Analysis]
91 Whitby LR, Obach RS, Simon GM, Hayward MM, Cravatt BF. Quantitative Chemical Proteomic Profiling of the in Vivo Targets of Reactive Drug Metabolites. ACS Chem Biol 2017;12:2040-50. [PMID: 28636309 DOI: 10.1021/acschembio.7b00346] [Cited by in Crossref: 20] [Cited by in F6Publishing: 17] [Article Influence: 5.0] [Reference Citation Analysis]
92 Wei S, Ma W, Zhang B, Li W. NLRP3 Inflammasome: A Promising Therapeutic Target for Drug-Induced Toxicity. Front Cell Dev Biol 2021;9:634607. [PMID: 33912556 DOI: 10.3389/fcell.2021.634607] [Cited by in F6Publishing: 1] [Reference Citation Analysis]
93 Brandt C, McGuire L, Uetrecht J. Severe cutaneous adverse reaction associated with antiseizure medications: Diagnosis, management, and prevention. Epilepsy Behav 2021;117:107844. [PMID: 33639435 DOI: 10.1016/j.yebeh.2021.107844] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 1.0] [Reference Citation Analysis]
94 Penman SL, Carter AS, Chadwick AE. Investigating the importance of individual mitochondrial genotype in susceptibility to drug-induced toxicity. Biochem Soc Trans 2020;48:787-97. [PMID: 32453388 DOI: 10.1042/BST20190233] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 2.0] [Reference Citation Analysis]
95 Flynn NR, Dang NL, Ward MD, Swamidass SJ. XenoNet: Inference and Likelihood of Intermediate Metabolite Formation. J Chem Inf Model 2020;60:3431-49. [DOI: 10.1021/acs.jcim.0c00361] [Cited by in Crossref: 6] [Cited by in F6Publishing: 6] [Article Influence: 6.0] [Reference Citation Analysis]
96 Sullivan A, Gibson A, Park BK, Naisbitt DJ. Are drug metabolites able to cause T-cell-mediated hypersensitivity reactions? Expert Opinion on Drug Metabolism & Toxicology 2014;11:357-68. [DOI: 10.1517/17425255.2015.992780] [Cited by in Crossref: 12] [Cited by in F6Publishing: 10] [Article Influence: 1.7] [Reference Citation Analysis]
97 Visentin M, Lenggenhager D, Gai Z, Kullak-Ublick GA. Drug-induced bile duct injury. Biochim Biophys Acta Mol Basis Dis. 2018;1864:1498-1506. [PMID: 28882625 DOI: 10.1016/j.bbadis.2017.08.033] [Cited by in Crossref: 26] [Cited by in F6Publishing: 22] [Article Influence: 6.5] [Reference Citation Analysis]
98 Shah F, Bell IM. Cutaneous Adverse Events Caused by Sulfonamide-Containing Drugs: Reality or Perception? J Med Chem 2020;63:7447-57. [DOI: 10.1021/acs.jmedchem.9b01932] [Cited by in Crossref: 4] [Cited by in F6Publishing: 5] [Article Influence: 4.0] [Reference Citation Analysis]
99 Ng TL, Narasimhan N, Gupta N, Venkatakrishnan K, Kerstein D, Camidge DR. Early-Onset Pulmonary Events Associated With Brigatinib Use in Advanced NSCLC. J Thorac Oncol 2020;15:1190-9. [PMID: 32135189 DOI: 10.1016/j.jtho.2020.02.011] [Cited by in Crossref: 13] [Cited by in F6Publishing: 12] [Article Influence: 13.0] [Reference Citation Analysis]
100 Foulkes DM, Byrne DP, Yeung W, Shrestha S, Bailey FP, Ferries S, Eyers CE, Keeshan K, Wells C, Drewry DH, Zuercher WJ, Kannan N, Eyers PA. Covalent inhibitors of EGFR family protein kinases induce degradation of human Tribbles 2 (TRIB2) pseudokinase in cancer cells. Sci Signal 2018;11:eaat7951. [PMID: 30254057 DOI: 10.1126/scisignal.aat7951] [Cited by in Crossref: 31] [Cited by in F6Publishing: 30] [Article Influence: 10.3] [Reference Citation Analysis]
101 Schultheiss JPD, Brand EC, Lamers E, van den Berg WCM, van Schaik FDM, Oldenburg B, Fidder HH. Earlier discontinuation of TNF-α inhibitor therapy in female patients with inflammatory bowel disease is related to a greater risk of side effects. Aliment Pharmacol Ther 2019;50:386-96. [PMID: 31310690 DOI: 10.1111/apt.15380] [Cited by in Crossref: 11] [Cited by in F6Publishing: 8] [Article Influence: 5.5] [Reference Citation Analysis]
102 Avila AM, Bebenek I, Bonzo JA, Bourcier T, Davis Bruno KL, Carlson DB, Dubinion J, Elayan I, Harrouk W, Lee S, Mendrick DL, Merrill JC, Peretz J, Place E, Saulnier M, Wange RL, Yao J, Zhao D, Brown PC. An FDA/CDER perspective on nonclinical testing strategies: Classical toxicology approaches and new approach methodologies (NAMs). Regulatory Toxicology and Pharmacology 2020;114:104662. [DOI: 10.1016/j.yrtph.2020.104662] [Cited by in Crossref: 16] [Cited by in F6Publishing: 14] [Article Influence: 16.0] [Reference Citation Analysis]
103 Atreya R, Goetz M. Molecular imaging in gastroenterology. Nat Rev Gastroenterol Hepatol. 2013;10:704-712. [PMID: 23856892 DOI: 10.1038/nrgastro.2013.125] [Cited by in Crossref: 31] [Cited by in F6Publishing: 30] [Article Influence: 3.9] [Reference Citation Analysis]
104 Eno MR, El-Gendy Bel-D, Cameron MD. P450 3A-Catalyzed O-Dealkylation of Lapatinib Induces Mitochondrial Stress and Activates Nrf2. Chem Res Toxicol 2016;29:784-96. [PMID: 26958860 DOI: 10.1021/acs.chemrestox.5b00524] [Cited by in Crossref: 17] [Cited by in F6Publishing: 17] [Article Influence: 3.4] [Reference Citation Analysis]
105 Baillie TA. Zielgerichtete kovalente Inhibitoren für das Wirkstoffdesign. Angew Chem 2016;128:13606-19. [DOI: 10.1002/ange.201601091] [Cited by in Crossref: 31] [Cited by in F6Publishing: 19] [Article Influence: 6.2] [Reference Citation Analysis]
106 Pirmohamed M, Ostrov DA, Park BK. New genetic findings lead the way to a better understanding of fundamental mechanisms of drug hypersensitivity. J Allergy Clin Immunol 2015;136:236-44. [PMID: 26254050 DOI: 10.1016/j.jaci.2015.06.022] [Cited by in Crossref: 58] [Cited by in F6Publishing: 52] [Article Influence: 9.7] [Reference Citation Analysis]
107 Lazarska KE, Dekker SJ, Vermeulen NPE, Commandeur JNM. Effect of UGT2B7*2 and CYP2C8*4 polymorphisms on diclofenac metabolism. Toxicol Lett 2018;284:70-8. [PMID: 29203276 DOI: 10.1016/j.toxlet.2017.11.038] [Cited by in Crossref: 26] [Cited by in F6Publishing: 17] [Article Influence: 6.5] [Reference Citation Analysis]
108 Lobach AR, Uetrecht J. Involvement of myeloperoxidase and NADPH oxidase in the covalent binding of amodiaquine and clozapine to neutrophils: implications for drug-induced agranulocytosis. Chem Res Toxicol 2014;27:699-709. [PMID: 24588327 DOI: 10.1021/tx500019u] [Cited by in Crossref: 25] [Cited by in F6Publishing: 24] [Article Influence: 3.6] [Reference Citation Analysis]
109 Vuda M, Kamath A. Drug induced mitochondrial dysfunction: Mechanisms and adverse clinical consequences. Mitochondrion 2016;31:63-74. [PMID: 27771494 DOI: 10.1016/j.mito.2016.10.005] [Cited by in Crossref: 30] [Cited by in F6Publishing: 25] [Article Influence: 6.0] [Reference Citation Analysis]
110 Gibson A, Ogese M, Pirmohamed M. Genetic and nongenetic factors that may predispose individuals to allergic drug reactions. Current Opinion in Allergy & Clinical Immunology 2018;18:325-32. [DOI: 10.1097/aci.0000000000000459] [Cited by in Crossref: 8] [Cited by in F6Publishing: 4] [Article Influence: 2.7] [Reference Citation Analysis]
111 Jaeschke H, Xie Y, McGill MR. Acetaminophen-induced Liver Injury: from Animal Models to Humans. J Clin Transl Hepatol. 2014;2:153-161. [PMID: 26355817 DOI: 10.14218/jcth.2014.00014] [Cited by in Crossref: 29] [Cited by in F6Publishing: 68] [Article Influence: 4.1] [Reference Citation Analysis]
112 Akai S, Oda S, Yokoi T. Strain and interindividual differences in lamotrigine-induced liver injury in mice. J Appl Toxicol 2019;39:451-60. [PMID: 30325050 DOI: 10.1002/jat.3736] [Cited by in Crossref: 3] [Article Influence: 1.0] [Reference Citation Analysis]
113 Usui T, Naisbitt DJ. Human leukocyte antigen and idiosyncratic adverse drug reactions. Drug Metabolism and Pharmacokinetics 2017;32:21-30. [DOI: 10.1016/j.dmpk.2016.11.003] [Cited by in Crossref: 20] [Cited by in F6Publishing: 18] [Article Influence: 5.0] [Reference Citation Analysis]
114 Metushi IG, Hayes MA, Uetrecht J. Treatment of PD-1(-/-) mice with amodiaquine and anti-CTLA4 leads to liver injury similar to idiosyncratic liver injury in patients. Hepatology 2015;61:1332-42. [PMID: 25283142 DOI: 10.1002/hep.27549] [Cited by in Crossref: 89] [Cited by in F6Publishing: 78] [Article Influence: 14.8] [Reference Citation Analysis]
115 Chaikuad A, Koch P, Laufer SA, Knapp S. Das Cysteinom der Proteinkinasen als Zielstruktur in der Arzneistoffentwicklung. Angew Chem 2018;130:4456-70. [DOI: 10.1002/ange.201707875] [Cited by in Crossref: 8] [Cited by in F6Publishing: 3] [Article Influence: 2.7] [Reference Citation Analysis]
116 Cho T, Wang X, Uetrecht J. Rotenone Increases Isoniazid Toxicity but Does Not Cause Significant Liver Injury: Implications for the Hypothesis that Inhibition of the Mitochondrial Electron Transport Chain Is a Common Mechanism of Idiosyncratic Drug-Induced Liver Injury. Chem Res Toxicol 2019;32:1423-31. [PMID: 31251588 DOI: 10.1021/acs.chemrestox.9b00116] [Cited by in Crossref: 7] [Cited by in F6Publishing: 8] [Article Influence: 3.5] [Reference Citation Analysis]
117 Mak A, Johnston A, Uetrecht J. Effects of immunization and checkpoint inhibition on amodiaquine-induced liver injury. J Immunotoxicol 2017;14:89-94. [PMID: 28279082 DOI: 10.1080/1547691X.2017.1290716] [Cited by in Crossref: 8] [Cited by in F6Publishing: 3] [Article Influence: 2.0] [Reference Citation Analysis]
118 Ferrajolo C, Verhamme KM, Trifirò G, 't Jong GW, Picelli G, Giaquinto C, Mazzaglia G, Stricker BH, Rossi F, Capuano A, Sturkenboom MC. Antibiotic-Induced Liver Injury in Paediatric Outpatients: A Case-Control Study in Primary Care Databases. Drug Saf 2017;40:305-15. [PMID: 28025733 DOI: 10.1007/s40264-016-0493-y] [Cited by in Crossref: 15] [Cited by in F6Publishing: 11] [Article Influence: 3.8] [Reference Citation Analysis]
119 Aboukaoud M, Israel S, Brautbar C, Eyal S. Genetic Basis of Delayed Hypersensitivity Reactions to Drugs in Jewish and Arab Populations. Pharm Res 2018;35:211. [PMID: 30225831 DOI: 10.1007/s11095-018-2472-8] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.3] [Reference Citation Analysis]
120 Ng W, Metushi IG, Uetrecht J. Hepatic effects of aminoglutethimide: A model aromatic amine. Journal of Immunotoxicology 2014;12:24-32. [DOI: 10.3109/1547691x.2013.867912] [Cited by in Crossref: 6] [Article Influence: 0.8] [Reference Citation Analysis]
121 Pels K, Dickson P, An H, Kodadek T. DNA-Compatible Solid-Phase Combinatorial Synthesis of β-Cyanoacrylamides and Related Electrophiles. ACS Comb Sci 2018;20:61-9. [PMID: 29298042 DOI: 10.1021/acscombsci.7b00169] [Cited by in Crossref: 13] [Cited by in F6Publishing: 12] [Article Influence: 4.3] [Reference Citation Analysis]
122 Hassan HM, Guo H, Yousef BA, Luyong Z, Zhenzhou J. Hepatotoxicity mechanisms of isoniazid: A mini-review: Hepatotoxicity mechanisms of isoniazid: A mini-review. J Appl Toxicol 2015;35:1427-32. [DOI: 10.1002/jat.3175] [Cited by in Crossref: 41] [Cited by in F6Publishing: 28] [Article Influence: 6.8] [Reference Citation Analysis]
123 Elzagallaai AA, Sultan EA, Bend JR, Abuzgaia AM, Loubani E, Rieder MJ. Role of Oxidative Stress in Hypersensitivity Reactions to Sulfonamides. J Clin Pharmacol 2020;60:409-21. [PMID: 31709574 DOI: 10.1002/jcph.1535] [Cited by in Crossref: 6] [Cited by in F6Publishing: 7] [Article Influence: 3.0] [Reference Citation Analysis]
124 Wewering F, Jouy F, Caliskan S, Kalkhof S, von Bergen M, Luch A, Zellmer S. Hepatic co-cultures in vitro reveal suitable to detect Nrf2-mediated oxidative stress responses on the bladder carcinogen o-anisidine. Toxicol In Vitro 2017;40:153-60. [PMID: 28089782 DOI: 10.1016/j.tiv.2017.01.006] [Cited by in Crossref: 2] [Cited by in F6Publishing: 2] [Article Influence: 0.5] [Reference Citation Analysis]
125 Susukida T, Aoki S, Kogo K, Fujimori S, Song B, Liu C, Sekine S, Ito K. Evaluation of immune-mediated idiosyncratic drug toxicity using chimeric HLA transgenic mice. Arch Toxicol 2018;92:1177-88. [PMID: 29150704 DOI: 10.1007/s00204-017-2112-9] [Cited by in Crossref: 9] [Cited by in F6Publishing: 5] [Article Influence: 2.3] [Reference Citation Analysis]
126 Chantelau EA, Prätor R, Prätor J. Insulin-induced localized lipoatrophy preceded by shingles (herpes zoster): a case report. J Med Case Rep 2014;8:223. [PMID: 24961832 DOI: 10.1186/1752-1947-8-223] [Cited by in Crossref: 7] [Cited by in F6Publishing: 3] [Article Influence: 1.0] [Reference Citation Analysis]
127 Chong LH, Li H, Wetzel I, Cho H, Toh Y. A liver-immune coculture array for predicting systemic drug-induced skin sensitization. Lab Chip 2018;18:3239-50. [DOI: 10.1039/c8lc00790j] [Cited by in Crossref: 7] [Cited by in F6Publishing: 5] [Article Influence: 2.3] [Reference Citation Analysis]
128 Hoppmann NA, Gray ME, McGuire BM. Drug-Induced Liver Injury in the Setting of Chronic Liver Disease. Clin Liver Dis 2020;24:89-106. [PMID: 31753253 DOI: 10.1016/j.cld.2019.09.006] [Cited by in Crossref: 3] [Cited by in F6Publishing: 1] [Article Influence: 1.5] [Reference Citation Analysis]
129 Hirayama N. Docking simulations between drugs and HLA molecules associated with idiosyncratic drug toxicity. Drug Metabolism and Pharmacokinetics 2017;32:31-9. [DOI: 10.1016/j.dmpk.2016.10.002] [Cited by in Crossref: 11] [Cited by in F6Publishing: 7] [Article Influence: 2.8] [Reference Citation Analysis]
130 Hammond S, Thomson P, Meng X, Naisbitt D. In-Vitro Approaches to Predict and Study T-Cell Mediated Hypersensitivity to Drugs. Front Immunol 2021;12:630530. [PMID: 33927714 DOI: 10.3389/fimmu.2021.630530] [Reference Citation Analysis]
131 Mencarelli A, Gunawan M, Yong KSM, Bist P, Tan WWS, Tan SY, Liu M, Huang EK, Fan Y, Chan JKY, Choi HW, Abraham SN, Chen Q. A humanized mouse model to study mast cells mediated cutaneous adverse drug reactions. J Leukoc Biol 2020;107:797-807. [PMID: 31922289 DOI: 10.1002/JLB.3MA1219-210RR] [Cited by in Crossref: 10] [Cited by in F6Publishing: 4] [Article Influence: 10.0] [Reference Citation Analysis]
132 Zhu X, Evans E. In Vitro Methods in Immunotoxicity Assessment. In: Will Y, Mcduffie JE, Olaharski AJ, Jeffy BD, editors. Drug Discovery Toxicology. Hoboken: John Wiley & Sons, Inc; 2016. pp. 193-200. [DOI: 10.1002/9781119053248.ch13] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.2] [Reference Citation Analysis]
133 Meng X, Al-Attar Z, Yaseen FS, Jenkins R, Earnshaw C, Whitaker P, Peckham D, French NS, Naisbitt DJ, Park BK. Definition of the Nature and Hapten Threshold of the β-Lactam Antigen Required for T Cell Activation In Vitro and in Patients. J Immunol 2017;198:4217-27. [PMID: 28438900 DOI: 10.4049/jimmunol.1700209] [Cited by in Crossref: 37] [Cited by in F6Publishing: 34] [Article Influence: 9.3] [Reference Citation Analysis]
134 Ichikawa T, Yamada T, Treiber A, Gnerre C, Segrestaa J, Seeland S, Nonaka K. Cross-species comparison of the metabolism and excretion of selexipag. Xenobiotica 2019;49:284-301. [PMID: 29468921 DOI: 10.1080/00498254.2018.1444814] [Cited by in Crossref: 1] [Cited by in F6Publishing: 1] [Article Influence: 0.3] [Reference Citation Analysis]
135 Uetrecht J. Mechanistic Studies of Idiosyncratic DILI: Clinical Implications. Front Pharmacol 2019;10:837. [PMID: 31402866 DOI: 10.3389/fphar.2019.00837] [Cited by in Crossref: 31] [Cited by in F6Publishing: 29] [Article Influence: 15.5] [Reference Citation Analysis]
136 Kenna JG. Human biology-based drug safety evaluation: scientific rationale, current status and future challenges. Expert Opin Drug Metab Toxicol 2017;13:567-74. [PMID: 28150517 DOI: 10.1080/17425255.2017.1290082] [Cited by in Crossref: 3] [Cited by in F6Publishing: 3] [Article Influence: 0.8] [Reference Citation Analysis]
137 Cho T, Uetrecht J. How Reactive Metabolites Induce an Immune Response That Sometimes Leads to an Idiosyncratic Drug Reaction. Chem Res Toxicol 2017;30:295-314. [DOI: 10.1021/acs.chemrestox.6b00357] [Cited by in Crossref: 73] [Cited by in F6Publishing: 65] [Article Influence: 14.6] [Reference Citation Analysis]
138 Hirasawa M, Hagihara K, Okudaira N, Izumi T. The Possible Mechanism of Idiosyncratic Lapatinib-Induced Liver Injury in Patients Carrying Human Leukocyte Antigen-DRB1*07:01. PLoS One 2015;10:e0130928. [PMID: 26098642 DOI: 10.1371/journal.pone.0130928] [Cited by in Crossref: 9] [Cited by in F6Publishing: 9] [Article Influence: 1.5] [Reference Citation Analysis]
139 Faulkner L, Gibson A, Sullivan A, Tailor A, Usui T, Alfirevic A, Pirmohamed M, Naisbitt DJ, Kevin Park B. Detection of Primary T Cell Responses to Drugs and Chemicals in HLA-Typed Volunteers: Implications for the Prediction of Drug Immunogenicity. Toxicol Sci 2016;154:416-29. [DOI: 10.1093/toxsci/kfw177] [Cited by in Crossref: 28] [Cited by in F6Publishing: 26] [Article Influence: 5.6] [Reference Citation Analysis]
140 Weston JK, Uetrecht J. Activation of Inflammasomes by Agents Causing Idiosyncratic Skin Reactions: A Possible Biomarker. Chem Res Toxicol 2014;27:949-51. [DOI: 10.1021/tx5001333] [Cited by in Crossref: 21] [Cited by in F6Publishing: 17] [Article Influence: 3.0] [Reference Citation Analysis]
141 Johnston A, Uetrecht J. Current understanding of the mechanisms of idiosyncratic drug-induced agranulocytosis. Expert Opinion on Drug Metabolism & Toxicology 2014;11:243-57. [DOI: 10.1517/17425255.2015.985649] [Cited by in Crossref: 48] [Cited by in F6Publishing: 41] [Article Influence: 6.9] [Reference Citation Analysis]
142 Bai X, Qin D, Yang L. Importance of substituents in ring opening: a DFT study on a model reaction of thiazole to thioamide. J Mol Model 2021;27:89. [PMID: 33611758 DOI: 10.1007/s00894-021-04704-5] [Reference Citation Analysis]
143 Naisbitt DJ, Olsson-Brown A, Gibson A, Meng X, Ogese MO, Tailor A, Thomson P. Immune dysregulation increases the incidence of delayed-type drug hypersensitivity reactions. Allergy 2020;75:781-97. [PMID: 31758810 DOI: 10.1111/all.14127] [Cited by in Crossref: 10] [Cited by in F6Publishing: 10] [Article Influence: 5.0] [Reference Citation Analysis]
144 Parasrampuria DA, Benet LZ, Sharma A. Why Drugs Fail in Late Stages of Development: Case Study Analyses from the Last Decade and Recommendations. AAPS J 2018;20:46. [PMID: 29536211 DOI: 10.1208/s12248-018-0204-y] [Cited by in Crossref: 21] [Cited by in F6Publishing: 16] [Article Influence: 7.0] [Reference Citation Analysis]
145 Stephenson ZA, Harvey RF, Pryde KR, Mistry S, Hardy RE, Serreli R, Chung I, Allen TE, Stoneley M, MacFarlane M, Fischer PM, Hirst J, Kellam B, Willis AE. Identification of a novel toxicophore in anti-cancer chemotherapeutics that targets mitochondrial respiratory complex I. Elife 2020;9:e55845. [PMID: 32432547 DOI: 10.7554/eLife.55845] [Cited by in Crossref: 4] [Cited by in F6Publishing: 2] [Article Influence: 4.0] [Reference Citation Analysis]
146 Vredenburg G, Elias NS, Venkataraman H, Hendriks DFG, Vermeulen NPE, Commandeur JNM, Vos JC. Human NAD(P)H:quinone Oxidoreductase 1 (NQO1)-Mediated Inactivation of Reactive Quinoneimine Metabolites of Diclofenac and Mefenamic Acid. Chem Res Toxicol 2014;27:576-86. [DOI: 10.1021/tx400431k] [Cited by in Crossref: 24] [Cited by in F6Publishing: 20] [Article Influence: 3.4] [Reference Citation Analysis]
147 Alzahrani A, Ogese M, Meng X, Waddington JC, Tailor A, Farrell J, Maggs JL, Betts C, Park BK, Naisbitt D. Dapsone and Nitroso Dapsone Activation of Naı̈ve T-Cells from Healthy Donors. Chem Res Toxicol 2017;30:2174-86. [PMID: 29045131 DOI: 10.1021/acs.chemrestox.7b00263] [Cited by in Crossref: 8] [Cited by in F6Publishing: 7] [Article Influence: 2.0] [Reference Citation Analysis]
148 Hammond S, Thomson PJ, Ogese MO, Naisbitt DJ. T-Cell Activation by Low Molecular Weight Drugs and Factors That Influence Susceptibility to Drug Hypersensitivity. Chem Res Toxicol 2020;33:77-94. [PMID: 31687800 DOI: 10.1021/acs.chemrestox.9b00327] [Cited by in Crossref: 4] [Cited by in F6Publishing: 5] [Article Influence: 2.0] [Reference Citation Analysis]
149 Gilbert AM. Recent advances in irreversible kinase inhibitors. Pharmaceutical Patent Analyst 2014;3:375-86. [DOI: 10.4155/ppa.14.24] [Cited by in Crossref: 14] [Cited by in F6Publishing: 12] [Article Influence: 2.0] [Reference Citation Analysis]
150 Dalvie D, Kalgutkar AS, Chen W. Practical approaches to resolving reactive metabolite liabilities in early discovery. Drug Metabolism Reviews 2015;47:56-70. [DOI: 10.3109/03602532.2014.984813] [Cited by in Crossref: 23] [Cited by in F6Publishing: 17] [Article Influence: 3.3] [Reference Citation Analysis]