Copyright
©The Author(s) 2019.
World J Stem Cells. Jun 26, 2019; 11(6): 297-321
Published online Jun 26, 2019. doi: 10.4252/wjsc.v11.i6.297
Published online Jun 26, 2019. doi: 10.4252/wjsc.v11.i6.297
Low-energy shock wave therapy | Conditions | Biological effects | References number |
In vivo studies | Wound-healing disturbances, tendinopathies, and non-healing bone fractures | Activation of angiogenic pathways with local release of trophic mediators | [72-77] |
Myocardial infarction in animal models | Improvement of vascularization at the infarction border zone; Mobilization of endogenous progenitor cells from bone marrow into the systemic circulation and to the damaged myocardium; Increase in VEGF gene and protein expression with endothelial cell proliferation | [82-88] | |
Human severe coronary artery disease or severe angina | Improvement of myocardial ischemia and chest pain | [89-90] | |
Human acute myocardial infarction | Suppression of left ventricular remodeling and enhancement of myocardial function | [91] | |
Spinal cord injury in rats | Induction of endogenous neural stem cells and functional improvement | [96] | |
Diabetic bladder dysfunction in rat model | Improvement of voiding function; Enhancement of innervation and vascularization | [97] | |
In vitro studies | Adipose- and bone marrow-derived mesenchymal stem cells | Induction of osteogenic differentiation | [92-94] |
Murine adipose derived stem cells | Stem cell proliferation and migration in an Erk1/2-dependent fashion | [81,95] |
- Citation: Facchin F, Canaider S, Tassinari R, Zannini C, Bianconi E, Taglioli V, Olivi E, Cavallini C, Tausel M, Ventura C. Physical energies to the rescue of damaged tissues. World J Stem Cells 2019; 11(6): 297-321
- URL: https://www.wjgnet.com/1948-0210/full/v11/i6/297.htm
- DOI: https://dx.doi.org/10.4252/wjsc.v11.i6.297