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iHuman+ (new): Agelessly renew, upgrade iHuman organ-system; iHuman-AI: Integration of iHuman brain-organsystem with AI; iHuman data technology, intelligence and blockchain. Developing in-vitro and in-vivo Human Platform of vascularized, innervated, functional, standard and live TissueOrgan-Organchain-System from hESC as ethical and unlimited source to improve clinical service (regenerative medicine, transplantation, precision medicine, etc.) and as efficient platform to upgrade human evaluation in health and medical studies. Clinical and biological design and R&D of the highly macro-porous structure of systemic and oral implant and scaffold for tissue, organ repair and reconstruction with additive manufacturing or 3D printing.