结肠腺癌中ID-1、ID-3和NF-κB的表达及意义

表1 二组中ID-1、ID-3和NF-κB表达的比较 n (%)

分组	n	ID-1		χ2	P	ID-3		χ2	P	NF-κB		χ2	P
		+	-			+	-			+	-
观察组	88	34 (38.6)	54 (61.4)	15.274	0.000	40 (45.5)	48 (54.5)	22.993	0.000	36 (40.9)	52 (59.1)	14.030	0.000
对照组	34	1 (2.9)	33 (97.1)			0 (0)	34 (100)			2 (5.9)	32 (94.1)

表2 观察组中ID-1、ID-3和NF-κB的阳性率在不同临床特征分组中的比较 n (%)

临床特征	n	ID-1		χ2	P	ID-3		χ2	P	NF-κB		χ2	P
		+	-			+	-			+	-
增殖指数				8.722	0.003			5.194	0.023			8.209	0.004
<25%	38	8 (21.1)	30 (78.9)			12 (31.6)	26 (68.4)			9 (23.7)	29 (76.3)
≥25%	50	26 (52.0)	24 (48.0)			28 (56.0)	22 (44.0)			27 (54.0)	23 (46.0)
浸润深度				9.067	0.003			7.789	0.005			4.962	0.026
未及浆膜	69	21 (30.4)	48 (69.6)			26 (37.7)	43 (62.3)			24 (34.8%)	45 (65.2)
浆膜及以外	19	13 (68.4)	6 (31.6)			14 (73.7%)	5 (26.3%)			12 (63.2%)	7 (36.8%)
分化程度				6.241	0.012			5.868	0.015			2.907	0.088
高-中	58	17 (29.3)	41 (70.7)			21 (36.2)	37 (63.8)			20 (34.5)	38 (65.5)
低	30	17 (56.7)	13 (43.3)			19 (63.3)	11 (36.7)			16 (53.3)	14 (46.7)
转移				0.779	0.377			0.503	0.478			7.587	0.006
无	69	25 (36.2)	44 (63.8)			30 (43.5)	39 (56.5)			23 (33.3)	46 (66.7)
有	19	9 (47.4)	10 (52.6)			10 (52.6)	9 (47.4)			13 (68.)	6 (31.6)

ID-1: DNA结合/分化抑制蛋白-1; ID-3: DNA结合/分化抑制蛋白-3; NF-κB: 核因子-κB.