MALDI-TOF-MS分析新疆食管鳞状细胞癌的蛋白组学

表1 食管鳞状癌细胞和食管正常上皮细胞的差异表达蛋白

Index	NCBI no	Mw/PI	Protein	score
01	gil5032057	11847/6.56	↑ protein S100-A11	75
02	gil11935049	66198/8.16	↑keratin 1	70
03	gil1869803	14878/6.29	↓ mammary-derived growth inhibitor	81
04	gil83754516	17268/6.18	↑Chain B, crystal structure of the chip-ubc13-uev1a complex	111
05	gil55960374	21244/7.63	- transgelin 2	150
06	gil186629	39832/4.72	- keratin 10	93
07	gil179032	22632/8.78	↑SM22	142
08	gil4507669	19697/4.84	↑translationally-controlled tumor protein	84
09	gil47577	23250/5.02	↑rho GDP-dissociation inhibitor 1 isoform a	96
10	gil4504183	23569/5.34	↑glutathione S-transferase P	141
11	gil662841	22427/7.83	↑heat shock protein 27	142
12	gil5454052	27871/4.68	↑14-3-3 protein sigma	198
13	gil2780871	16342/7.14	↑Chain B, Proteasome Activator Reg(Alpha)	86
14	gi62738525	43071/5.72	↑Chain A, The 2.8 A Structure Of A Tumour Suppressing Serpin	162
15	gil301030821	36874/6.17	↑c-myc promoter-binding protein 1	203
16	gil239552	44564/6.35	↓squamous cell carcinoma antigen	95
17	gil20150229	13159/5.71	↑Chain A, Crystal Structure Of The Mrp14 Complexed With Chaps	91

"↑"表示在食管癌中表达上调的差异点, "↓"表示在食管癌中表达下调的差异点, "-"表示只在食管癌中表达的差异点.