食管鳞癌组织及周围正常食管黏膜组织差异表达基因的筛选

表1 筛选结果下调的部分差异表达基因

基因名称	下调基因功能	染色体定位
ACTA1	actin, alpha 1, skeletal muscle	1q42.13-q42.2
MYH7	myosin, heavy chain 1, cardiac muscle, beta	14q12
CKM	creatine kinase, muscle	19q13.2-q13.3
TNNC1	troponin C type 1 (slow)	3p21.3-p14.3
MB	myoglobin	22q13.1
MYH2	myosin, heavy chain 2, skeletal muscle, adult	17p13.1
TFF1	trefoil factor 1 (breast cancer, estrogen-inducible sequence expressed in)	21q22.3
OGN	osteoglycin (osteoinductive factor, mimecan)	9q22

表2 筛选结果上调的部分差异表达基因

基因名称	上调基因功能	染色体定位
MMP-3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)	11q22.3
COL11A1	collagen, type XI, alpha 1	1p21
SPANXD	SPANX family, member D	Xq27.1
CALB1	calbindin 1, 28 kDa	8q21.3-q22.1
SPANXA1	sperm protein associated with the nucleus, X-linked, family member A1	Xq27.1
SPRR2G	small proline-rich protein 2G	1q21-q22
MAGEA2B	melanoma antigen family A, 2B	Xq28
MMP-1	matrix metallopeptidase 1 (interstitial collagenase)	11q22.3