临床经验
Copyright ©The Author(s) 2009.
世界华人消化杂志. 2009-10-08; 17(28): 2944-2947
在线出版 2009-10-08. doi: 10.11569/wcjd.v17.i28.2944
表1 2组患者一般资料比较
分组平均年龄(岁)男:女腰臀围比BMI
NAFLD组41.90±5.491.46:11.066a25.71±1.68a
对照组42.26±4.951.50:10.74320.46±1.40
表2 2组患者临床资料比较 (mean±SD)
分组ALT(U/L)AST(U/L)GGT(U/L)TG(mmol/L)Tchol(mmol/L)HDL(mmol/L)FBG(mmol/L)HOMA-IR脂联素(mg/L)瘦素
NAFLD组68.97±18.71a38.52±9.0849.85±14.86a2.63±0.47a5.09±0.981.06±0.13a6.37±0.70a4.86±0.63a12.69±2.83a12.37±1.99a
对照组24.67±6.6129.97±6.1929.8±9.811.26±0.374.69±0.511.46±0.274.66±0.551.91±0.4122.83±4.615.20±1.03
表3 脂联素、瘦素与相关因素Spearman分析
ALT(U/L)GGT(U/L)TG(mmol/L)HDL(mmol/L)FBG(mmol/L)WHRBMIHOMA-IR
瘦素
γ值0.760.570.767-0.640.8260.8790.790.877
P<0.01<0.01<0.01<0.01<0.01<0.01<0.01<0.01
脂联素
γ值-0.643-0.489-0.6710.567-0.710-0.732-0.719-0.752
P<0.01<0.01<0.01<0.01<0.01<0.01<0.01<0.01
表4 脂联素、瘦素与相关因素Logistic回归分析
因变量自变量ORγ值P95%CI
瘦素HOMA-IR2.560.914<0.010.46-1.42
WHR3.558.175<0.013.41-12.94
FBG1.760.564<0.010.11-1.01
脂联素HOMA-IR0.14-0.495<0.011.19-2.79
BMI0.52-0.314<0.010.24-1.06

引文著录: 李异玲, 田忠, 杨淼, 王炳元. 非酒精性脂肪性肝病患者血清瘦素、脂联素的变化. 世界华人消化杂志 2009; 17(28): 2944-2947