以iTRAQ技术分析大鼠肝纤维化发展成肝癌过程中肝组织差异表达的蛋白质

表2 大鼠肝纤维化发展成肝癌过程中肝组织表达下调的蛋白

Accession	Protein Description	Ratio
		113:117	114:117	115:117	116:117
sp|P02761	Major urinary protein	0.213	0.338	0.373	0.208
tr|G3V697	Clock homolog	0.180	0.490	0.471	0.667
sp|O09171	Betaine--homocysteine S-methyltransferase 1	0.644	0.446	0.508	0.337
sp|P04762	Catalase	0.577	0.547	0.519	0.576
tr|M0RDH0	Glycine N-methyltransferase	0.546	0.393	0.555	0.510
sp|Q8CHM7	2-hydroxyacyl-CoA lyase	0.652	0.579	0.590	0.581
sp|Q5M876	N-acyl-aromatic-L-amino acid amidohydrolase	0.663	0.599	0.593	0.613
sp|P04904	Glutathione S-transferase	0.481	0.429	0.649	0.499
sp|P52759	Ribonuclease UK114	0.522	0.656	0.396	0.546
tr|D3ZIC2	Protein Uroc1	0.450	0.395	0.679	0.245
sp|P07632	Superoxide dismutase	0.697	0.648	0.769	0.498
sp|Q4QQW3	Hydroxyacid-oxoacid transhydrogenase	0.646	0.396	0.772	0.425