Clinical and experimental study on regional administration of phosphorus 32 glass microspheres in treating hepatic carcinoma

Figure 5 ① First week of internal irradiation irreg ularly distorted nuclei of hepatocytes, aggregation of heterochromatin at the pe riphery of nuclei, distension of perinuclei gap (solid arrow); decreased number of mitochondria in cytoplasm with heavy or light stained substance: dilatation of rough endoplasmic reticulum, depleted glycogen, and increased lysosomes and vacuoles. × 10000 ② 16wk of internal irradiation: normal configuration of hepatocytes, plenty of plasmic mitochondria with normal cristae (curved arrow), no distention of the rough endoplasmic reticulum pool (small arrow), nor mal cellular conjunction (solid arrow). × 6000