Current medical therapy for ulcerative colitis

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 5, Issue 1

This Article

Citation of this article

Corresponding Author of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

All Articles published online

Item

Count

PDF

211

HTML

1997

Tables (1-5)

113

Sum=2321

Feb 15, 1999 (publication date) through Apr 16, 2024

Times Cited of This Article

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Review

World J Gastroenterol. Feb 15, 1999; 5(1): 64-72
Published online Feb 15, 1999. doi: 10.3748/wjg.v5.i1.64

Table 4 Immunosuppressives used in inflammatory bowel diseases

Drug	Mode of action	Mechanism of action
AZT/6-MP	Inhibition of ribonucleotide sysnthesis	Inhibition of proliferation of T-cell clones
Methotrexate	Folic acid inhibitor	Inhibition of T and B-cell
		Function decrease of IL-1 and IL-6
Cyclosporin (CsA	Inhibition of T-cell-receptor-stimulated	Inhibition of IL-2 production and
Tacolimua (FK 506)	Transcription of lymphokine genes	IL-2 receptors; inhibition of cytokines(TNFα, IFNγ)
Mycophenolate	Inhibition of guanosin nucleotide synthesis

Citation: Xu CT, Pan BR. Current medical therapy for ulcerative colitis. World J Gastroenterol 1999; 5(1): 64-72
URL: https://www.wjgnet.com/1007-9327/full/v5/i1/64.htm
DOI: https://dx.doi.org/10.3748/wjg.v5.i1.64