Primary hyperparathyroidism-induced acute pancreatitis in pregnancy: A systematic review with a diagnostic-treatment algorithm

Table 2 Comparison of the characteristics between the group of fetal/child survival or death due to maternal primary hyperparathyroidism-induced acute pancreatitis during pregnancy

Variables	Entire cohort, n = 54, 100.0%	Child alive, n = 49, 90.7%	Fetal/child death, n = 5, 9.3%	P value
Age in years	29 (26-32)	29 (26-32)	28 (28-36)	0.77
Previous pregnancies	2 (1-2)	2 (1-2)	2 (1-7)	0.98
Previous deliveries	1 (0-1)	1 (0-1)	1 (1-5)	0.52
Pancreatitis occurrence week	27 (20-33)	28 (22-33)	16 (13-26)	0.08
Pancreatitis post-partum	4 (7.4)	4 (8.2)	0 (-)	1.00
Surgical management	11 (20.4)	10 (20.4)	1 (20.0)	0.73
Amylase in IU/L	1399 (519-2072)	1500 (510-2072)	1113 (752-2004)	0.89
Lipase in IU/L	2072 (893-2804)	2072 (869-2808)	1415 (751-5664)	0.95
Calcium in mmol/L	3.5 (3.1-3.9)	3.3 (3.1-3.8)	4.1 (3.8-4.7)	0.009
Phosphorus in mmol/L	0.7 (0.7-0.7)	0.7 (0.7-0.7)	0.7 (0.5-0.8)	0.89
PTH in pg/mL	384 (123-910)	302 (122-910)	1914 (910-3330)	0.003
Abortion	2 (3.7)	0 (-)	2 (40.0)	0.007
Complex delivery	7 (13.0)	4 (8.2)	3 (60.0)	0.01
Delivery week	36 (36-38)	36 (36-39)	34 (19-39)	0.12
Mother death	5 (9.3)	4 (8.2)	1 (20.0)	0.40

Data are n (%) or median (Q1-Q3). PHT: Parathormone.