Long noncoding RNA negative regulator of antiviral response contributes to pancreatic ductal adenocarcinoma progression via targeting miR-299-3p

Figure 1 Relative expression of negative regulator of antiviral response in pancreatic cancer tissues and cells and its clinical significance. A: The negative regulator of antiviral response (NRAV) expression profile across all tumor samples and paired normal tissues; B: The NRAV expression of pancreatic adenocarcinoma in tissues was significantly higher than that in normal pancreas tissues; C: Expression of NRAV in patients divided by cancer stages using expression data from The Cancer Genome Atlas (TCGA) database; D: Overall survival analyzed by GEPIA based on the TCGA database; E: Disease-free survival analyzed by GEPIA based on the TCGA database; F: Quantitative real-time polymerase chain reaction analysis measured NRAV expression level in four pancreatic cancer and normal cell lines. ^cP < 0.001; ^dP < 0.0001. PAAD: Pancreatic adenocarcinoma; TPM: Transcripts per million; NRAV: Negative regulator of antiviral response; HR: Hazard ratio.