Case Report
Copyright ©The Author(s) 2022.
World J Gastroenterol. Sep 14, 2022; 28(34): 5076-5085
Published online Sep 14, 2022. doi: 10.3748/wjg.v28.i34.5076
Table 3 Histopathological features, treatments, and outcome of 16 transplant patients with gastrointestinal stromal tumor
Size (mm)
Mitotic count
Fletcher’s criteria
Joensuu’s criteria
Mutation identified
Initial adjuvant treatment
Second line treatment
Agaimy and Wünsch[11]35< 5/50LowLowNot describedYesNoNot describedAlive and relapse free at 68 mo
Agaimy and Wünsch[11]23014/50HighHighNot describedYesNoNot describedNot described
Saidi et al[19]251/50LowHighNot describedYesNoNot describedAlive and relapse free at 18 mo
Camargo et al[22]505/50IntermediateHighNot describedYesNoNot describedAlive and relapse free at 20 mo
Tu et al[18]452-3/50LowLowPDGFRA exon 18 V824VYesNoNot describedAlive and relapse free 24 mo
Mulder et al[12]50> 10/50HighHighNot describedYesNoImatinib 400 mg/d then 200 mg/dDied 44 mo
Mrzljak et al[20]101/50Very lowVery lowNot describedYesNoNoDied 3 yr after from acute leukemia
Cimen et al[13]15014/50HighHighKIT T574delYesImatinib 400 mg/dNot describedAlive and relapse free at 12 mo
Cheung et al[14]309/50IntermediateIntermediateNot describedYesNoNoDied from pneumonia at 2 yr
Cheung et al[14]Not describedNot describedNot describedNot describedNot describedNoImatinib 400 mg/d for 1 yrSwitch CsA to sirolimusAlive and relapse free at 10 yr
Patiño et al[15]58Not describedIntermediate or highIntermediate of highNot describedYesNoImatinib 400 mg/dAlive and relapse free/5 yr after imatinib initiation
Xie et al[21]10< 5/50Very lowVery lowKIT exon 11 YesNoNoNot described
Elkabets et al[17]31Not describedNot describedNot describedNot describedYesNoNoAlive and relapse free at 40 mo
Takahashi et al[16]11020/50HighHighKIT exon 11YesImatinib 400 mg/d reduced to 3000 mg/dNoAlive and relapse free at 18 mo
Stammler et al272/5LowLowKIT exon 11YesNoNoAlive and relapse free at 2 mo
Stammler et al5110/50HighHighPDGFRA exon 18YesNoSunitinib then regorafenib then dasatinibDied 56 mo later