Sirtuin 1 alleviates endoplasmic reticulum stress-mediated apoptosis of intestinal epithelial cells in ulcerative colitis

Figure 5 Sirtuin 1 clinically and histologically ameliorates dextran sodium sulfate-induced colitis. A: Disease activity index was calculated; B: Hematoxylin-eosin staining of colon sections was performed (×100); C: Histological scores of stained sections were calculated. Each value is presented as the mean ± SD. ^bP < 0.01 vs UC; ^cP < 0.001 vs UC; ^dP < 0.001 vs control. UC: Ulcerative colitis; NAM: Nicotinamide.