Basic Study
Copyright ©The Author(s) 2019.
World J Gastroenterol. Apr 28, 2019; 25(16): 1964-1974
Published online Apr 28, 2019. doi: 10.3748/wjg.v25.i16.1964
Figure 3
Figure 3 Effect of circ-PRKCI on the growth of HepG2 cells. A: Two specific siRNAs targeting circ-PRKCI; B: Rnase R enzyme digestion of linear PRKCI, and circ-PRKCI silencing by specific si-RNA1 and si-RNA2; C: After circ-PRKCI silencing, the apoptosis of tumor cells was increased (bP < 0.01); D: The expression plasmid and control plasmid of circ-PRKCI were constructed. E: Overexpression of circ-PRKCI increased the invasiveness of cancer cells, while circ-PRKCI silencing significantly decreased their invasiveness; F: Cell proliferation after silencing or overexpression of circ-PRKCI. CMV: Cytomegalovirus; GFP: Green fluorescent protein.