Retrospective Cohort Study
Copyright ©The Author(s) 2018.
World J Gastroenterol. Dec 21, 2018; 24(47): 5403-5414
Published online Dec 21, 2018. doi: 10.3748/wjg.v24.i47.5403
Table 5 Comparison of patients’ characteristics by age
ValidNo.Below 60 yr
Above 60 yr
P value
Number%Number%
Patients1111113531.527668.5
Male gender111471542.933242.10.941
Ambulatory111783085.734863.20.011
CDI risk factors
Prior hospitalization111802262.935876.30.142
Antibiotics use108892880.036183.60.649
PPI usage11037925.732837.30.230
Chemotherapy11119720.031215.80.584
IBD111201440.0367.90.000
Steroid usage11117925.73810.50.039
Fever7621735.031425.00.391
Severe1112038.631722.40.079
Route
Lower GI111501234.333850.00.254
Upper GI111124822.931621.1
Capsules111371542.932228.9
0-1 Previous CDI10724822.931622.20.941
2+ previous CDI107832777.135677.8
Indication
Refractory11129822.932127.6
Recurrent111822777.135572.4
Prior therapy
Metronidazole110982982.936980.00.722
Vancomycin10910935100.037498.70.493
Combination109311234.331925.70.352
Outcomes
Success111973394.336484.20.137
Recurrence by 6 m99167203914.10.443
Death1111100311100.00.018
Adverse events10719514.331419.40.512
MeanSDMeanSDSigma
Age (yr)11137.2614.7277.078.90.000
Charlson comorbidity score811.291.956.352.30.000
Previous CDI episodes (n)1072.631.92.381.510.455
Time from 1st CDI (d)89198.75279.04102.68112.190.024
Creatinine (mg/dL)760.910.511.671.630.051
Albumin (mg/L)543.510.993.170.690.153
WBC (103/dL)7611.3390.3614.7819.860.468