Differentiation of intrahepatic cholangiocarcinoma from hepatocellular carcinoma in high-risk patients: A predictive model using contrast-enhanced ultrasound

Table 4 Univariate and multivariate logistic regression of independent variables in the prediction of intrahepatic cholangiocarcinoma

Factors	Univariate analysis		Multivariate analysis
	OR (95%CI)	P value	OR (95%CI)	P value
Gender (female)	0.149 (0.046, 0.403)	< 0.001	0.190 (0.034,0.908)	0.044
Age (yr)
> 40	0.786 (0.220, 2.618)	0.696	NA	NA
> 50	1.630 (0.778, 3.450)	0.197	NA	NA
AFP (mg/L) > 20	0.331 (0.148, 0.717)	0.006	0.508 (0.107, 2.212)	0.370
CA199 (U/mL) > 35	10.577 (4.152, 31.070)	< 0.001	5.352 (1.108, 30.336)	0.043
CEUS score	12.188 (5.475, 37.787)	< 0.001	14.078 (5.608, 52.831)	< 0.001

Numbers in parentheses are raw data, with 95%CI in parentheses. ICC: Intrahepatic cholangiocarcinoma; OR: Odds ratio; NA: Not available; AFP: Alpha-fetoprotein; CEUS: Contrast-enhanced ultrasound.