Fatty liver in hepatitis C patients post-sustained virological response with direct-acting antivirals

Table 3 Comparison of pre-treatment vs post-sustained virological response characteristics in patients with and without post-sustained virological response steatosis

	Patients without steatosis n = 53			Patients with steatosis n = 48
	Pretreatment	Post SVR	P value	Pretreatment	Post SVR	P value
Body mass index (kg/m2)	25.5 ± 4.0	26.1 ± 6.9	NS	30.0 ± 8.5	29.0 ± 6.6	NS
Weight (Lbs.)	161.9 ± 32.6	161.0 ± 33.4	NS	187.3 ± 55.8	186.1 ± 51.3	NS
Laboratory panel (mean ± SD)
HCV vial load log10 IU/mL	6.1 ± 1.0	0.0 ± 0.0	< 0.0001	6.3 ± 0.8	0.0 ± 0.0	< 0.0001
AST (U/L)	43.3 ± 35.6	20.2 ± 5.4	< 0.0001	61.3 ± 44.7	22.9 ± 9.8	< 0.0001
ALT (U/L)	55.6 ± 60.9	15.3 ± 5.5	< 0.0001	68.78 ± 52.8	20.4 ± 16.5	< 0.0001
Alkaline phosphatase (U/L)	78.5 ± 43.1	70.8 ± 28.8	0.01	75.5 ± 21.8	71.3 ± 19.4	0.04
Albumin (g/dL)	4.2 ± 0.5	4.4 ± 0.3	0.006	4.3 ± 0.2	4.5 ± 0.6	0.006
Bilirubin total (mg/dL)	0.6 ± 0.2	0.6 ± 0.3	NS	0.6 ± 0.3	0.6 ± 0.2	NS
Fasting glucose (mg/dL)	95.6 ± 31.9	96.6 ± 11.1	NS	103.0 ± 27.5	107.8 ± 30.5	NS
FibroScan (mean ± SD)
Fibrosis score (kPa)	7.1 ± 2.1	5.3 ± 1.5	< 0.0001	7.7 ± 1.7	7.0 ± 4.8	0.0037

SVR: Sustained virological response; HCV: Hepatitis C virus; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase.