Differential analysis of lymph node metastasis in histological mixed-type early gastric carcinoma in the mucosa and submucosa

Table 2 Risk factors for lymph node metastasis in early gastric carcinoma

Variable	Univariate analysis			Multivariate analysis
	OR	95%CI	P value	OR	95%CI	P value
Age (yr)			0.005
≤ 60	1.00
> 60	0.37	0.18-0.74
Gender			0.044
Male	1.00
Female	1.97	1.02-3.82
Size (cm)	1.33	1.04-1.71	0.022			0.154
Location			0.010
U	1.00
M/L	4.85	1.45-16.19
LV invasion			< 0.001
Absent	1.00
Present	18.4	8.31-40.72
Gross type			0.034
Elevated	1.00
Flat/depressed	2.32	1.07-5.04
Ulcer			0.031			0.256
Absent	1.00
Present	2.15	1.07-4.31
H. pylori infection			0.346
Absent	1.00
Present	1.46	0.67-3.19
Depth of invasion			0.001			0.023
Mucosa	1.00
Submucosa	3.41	1.70-6.83		4.58	1.23-16.97
Histological type			0.001			0.054
Pure D	1.00
Pure U	2.99	1.39-6.44	0.005	4.97	1.21-20.39	0.026
Mixed-type	4.45	1.91-10.36	0.001	5.84	1.05-32.61	0.044
Depth of invasion/histological type						0.822

MT: Mixed-type; PU: Pure undifferentiated; PD: Pure differentiated; U: Upper; M/L: Middle/lower; LV: Lymphovascular; LNM: Lymph node metastasis.