Copyright
©The Author(s) 2017.
World J Gastroenterol. Feb 28, 2017; 23(8): 1406-1411
Published online Feb 28, 2017. doi: 10.3748/wjg.v23.i8.1406
Published online Feb 28, 2017. doi: 10.3748/wjg.v23.i8.1406
Table 4 Observed toxicity according to common terminology criteria for adverse events grading n (%)
| Adverse event | TOMOX (n = 18) | FOLFOX (n = 24) | P value | ||
| All grade | Severe | All grade | Severe | ||
| Hematological | |||||
| Anemia | 7 (39) | 11 (46) | 0.212 | ||
| Leucopenia | 3 (16) | 12 (50) | 1 (4) | 0.026 | |
| Neutropenia | 1 (5) | 6 (25) | 1 (4) | 0.094 | |
| Thrombocytopenia | 8 (44) | 13 (54) | 3 (12) | 0.533 | |
| Nonhematological | |||||
| Elevation of liver enzymes | 18 (100) | 9 (50) | 19 (79) | 7 (29) | 0.039 |
| Elevation of bilirubin | 17 (94) | 3 (17) | 23 (95) | 4 (17) | 0.834 |
| Nausea/vomiting | 14 (78) | 17 (71) | 0.839 | ||
| Asthenia | 13 (72) | 12 (50) | 0.414 | ||
| Neuropathy | 5 (28) | 7 (29) | 1 (4) | 0.921 | |
| Pain | 14 (78) | 7 (39) | 19 (79) | 13 (54) | 0.914 |
| Fever | 6 (33) | 11 (46) | 0.558 | ||
- Citation: Guo JH, Zhang HY, Gao S, Zhang PJ, Li XT, Chen H, Wang XD, Zhu X. Hepatic artery infusion with raltitrexed or 5-fluorouracil for colorectal cancer liver metastasis. World J Gastroenterol 2017; 23(8): 1406-1411
- URL: https://www.wjgnet.com/1007-9327/full/v23/i8/1406.htm
- DOI: https://dx.doi.org/10.3748/wjg.v23.i8.1406