Restoration of energy level in the early phase of acute pediatric pancreatitis

Figure 1 Early events in acute pancreatitis. Bile acids, ethanol, fatty acids or their non-oxidative metabolites, fatty acid ethyl esthers, induce calcium overload, causing mitochondrial damage and a resultant decrease in intracellular ATP concentration both in acinar and ductal cells. This will lead to general energy depletion in the pancreas.