Copyright ©The Author(s) 2017.
World J Gastroenterol. Sep 7, 2017; 23(33): 6030-6048
Published online Sep 7, 2017. doi: 10.3748/wjg.v23.i33.6030
Table 2 Proposed schedule of prednisone tapering during remission-induction therapy in children[2,12]
Prednisone mg/kg/dAzathioprine
Week 12.0Check transaminase levels every week before reducing the prednisone dose: if transaminase levels stop decreasing, add azathioprine starting with 0.5 mg/kg per day, if jaundice is subsiding, at increasing doses up to 2-2.5 mg/kg/d until biochemical control
Week 21.75
Week 31.50
Week 41.25
Week 51.00
Week 60.75
Week 70.50
Week 8-90.25
Week 10-110.10-0.20
If severe steroid side effects: consider reducing to 2.5 mg/d for 2 wk and then stopping prednisone