Mechanisms of intrahepatic triglyceride accumulation

Table 2 Overview on drug-induced micro- or macrovesicular forms of fatty liver disease (adapted from[108,123])

Causes of drug-induced fatty liver disease
Predominantly microvesicular pattern:
Tetracyclin
Valproic acid
Amiodarone
Glucocorticoids
5-FU
Margosa oil
Predominantly macrovesicular pattern:
Acetylsalicylic acid (intoxication)
Tamoxifen
Mixed pattern:
Antiretroviral agents (e.g., didanosine, stavudine)
Methotrexate