Observational Study
Copyright ©The Author(s) 2015.
World J Gastroenterol. Jul 7, 2015; 21(25): 7842-7850
Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7842
Table 5 Cumulative effects of familial history of hepatitis B virus on hepatitis B virus infection
VariablesHBsAg negativeHBsAg positiveOR (95%CI)P value
Mother10313173.57 (3.12-4.08)< 0.001
Father24884321.95 (1.75-2.17)< 0.001
Spouse (≥ 20 yr)33635311.02 (1.00-1.04)0.041
Offspring (≥ 20 yr)18172831.61 (1.41-1.83)< 0.001
Siblings10593533.10 (2.73-3.51)< 0.001
Other families10611301.57 (1.30-1.89)< 0.001
Combined familial history of HBV and HBV infection
0123472 (92.29)9525 (84.88)1-
19838 (7.36)1562 (13.95)1.93 (1.82-2.05)< 0.001
2462 (0.34)121 (1.05)3.19 (2.60-3.92)< 0.001
3-619 (0.01)14 (0.12)9.82 (4.80-20.11)< 0.001
Trend< 0.0011
0123472 (92.29)9525 (84.88)1-
1-610319 (7.71)1697 (15.12)2.00 (1.89-2.12)< 0.001