Thrombomodulin in the management of acute cholangitis-induced disseminated intravascular coagulation

Table 1 Diagnostic criteria for disseminated intravascular coagulation as defined by the Japanese Association for Acute Medicine

	Score
Systemic inflammatory response syndrome criteria1
≥ 3	1
0-2	0
Platelet count (× 103/L)
< 80 or > 50% decrease within 24 h	3
≥ 80 and < 120; or > 30% decrease within 24 h	1
≥ 120	0
Prothrombin time (Value of patient/Normal value)
≥ 1.2	1
< 1.2	0
Fibrin/fibrinogen degradation products (mg/L)
≥ 25	3
≥ 10 and < 25	1
< 10	0
Diagnosis
≥ 4 points	DIC

¹Systemic inflammatory response syndrome criteria: Fever of more than 38 °C or less than 36 °C; Heart rate of more than 90 beats per min; Respiratory rate of more than 20 breaths per minute or a PaCO₂ level of less than 32 mmHg; Abnormal white blood cell count (> 12000/μL or < 4000/μL or > 10% bands). DIC: Disseminated intravascular coagulation.