Review
Copyright ©The Author(s) 2015.
World J Gastroenterol. Jan 7, 2015; 21(1): 102-111
Published online Jan 7, 2015. doi: 10.3748/wjg.v21.i1.102
Table 1 Summary of extra-intestinal disorders associated with gut microbiota
Extra-intestinal disordersRef.Publication yearStudy type
Metabolic diseases
Metabolic syndromeVrieze et al[61]2012RCT1
ObesityTurnbaugh et al[54]2009Observational study
Armougom et al[56]2009Observational study
Schwiertz et al[55]2010Observational study
Greenblum et al[53]2012Observational study
Parks et al[52]2013Experimental study
Type 2 diabetes mellitusQin et al[59]2012Observational study
Cardiovascular diseasesWang et al[62]2011Experimental study
Tang et al[65]2013Experimental study
Koeth et al[66]2013Experimental study
Non-alcoholic fatty liverRabot et al[73]2010Experimental study
Le Roy et al[68]2013Experimental study1
Neuropsychiatric disorders
Parkinson’s diseaseAnanthaswamy[74]2011Case report1
Multiple sclerosisBorody et al[76]2011Case report1
Myoclonus dystoniaBorody et al[78]2011Case report1
AutismFinegold et al[79]2002Observational study
Song et al[82]2004Observational study
Chronic fatigue syndromeBorody et al[84]2012Cohort study1
Frémont et al[83]2013Observational study
Autoimmune disorders
ITPBorody et al[85]2011Case report1
ArthritisScher et al[88]2013Observational study
Abdollahi-Roodsaz et al[86]2014Experimental study
SS and SLESzymula et al[91]2014Experimental study
Hashimoto’s thyroiditisCorapçioğlu et al[93]2002Observational study
Strieder et al[92]2003Observational study
Sasso et al[96]2004Observational study
Effraimidis et al[95]2011Observational study
Allergic disorders
AtopyDotterud et al[107]2010RCT
Herbst et al[101]2011Experimental study
Schabussova et al[105]2012Experimental study
AsthmaJang et al[104]2012Experimental study
Stensballe et al[102]2013Observational study
Extra-intestinal tumorsGold et al[15]2004Observational study
Mammary tumorsRao et al[111]2006Experimental study
Rao et al[112]2006Experimental study
Hepatocellular carcinomaFox et al[114]2010Experimental study
LymphomaYamamoto et al[115]2013Experimental study